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Musculoskeletal/Hip Fracture

Musculoskeletal

Hip Fracture

16

Pipeline Programs↗

22

Active Trials↗

15

Companies Involved↗

Hip Fracture is an emerging landscape with 16 programs across 15 companies.

Intelligence

Pipeline Metrics

Competitive Density

50/100

Pipeline Velocity

36/100

Mech. Concentration

40/100

Completion Rate

69/100

Attrition Rate

19/100

Pipeline

Programs by Phase

Preclinical16

Enoxaparin Sodium

Sanofi

Clopidogrel

Sanofi

Morphine

Hikma Pharmaceuticals LLC

Celecoxib

Philadelphia Eye Associates

Fentanyl

Cephalon

Phase 1

No programs

Phase 2

No programs

Phase 3

No programs

Approved

No programs

Analysis

Trial Status

124

clinical trials

Completed54 · 44%

Unknown status24 · 19%

Terminated14 · 11%

Recruiting12 · 10%

Withdrawn10 · 8%

Not yet recruiting8 · 6%

Other2 · 2%

Clinical Trials

Trial Activity

124 trials

Monitored Anesthesia Care and Soft Tissue Infiltration With Local Anesthesia for Older Adults With Hip Fracture: A Multi-Center Feasibility Randomized Clinical Trial

Recruiting·NNYU Langone Health·Preclinical·NCT07897656·140 enrolled

Effect of Total Intravenous Anesthesia Versus Inhalational Anesthesia on Postoperative Quality of Recovery and Cognitive Outcomes in Patients Undergoing Hip Fracture Surgery

Recruiting·SSehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital·N/A·NCT07860996·110 enrolled

Influence of Cemented Cephalic Augmentation on the Outcome of Osteosynthesis Using Intramedullary Nailing in the Surgical Treatment of Pertrochanteric Hip Fractures in the Elderly

Recruiting·DDiego Matías Domínguez Prado·Preclinical·NCT06634290·314 enrolled

INTACT-HIP: INTravenous Acetaminophen vs. Oral Randomized Controlled Trial in HIP Fracture Patients - a Feasibility Trial

Recruiting·UUniversity Health Network, Toronto·Approved·NCT05425355·42 enrolled

Effectiveness of the Delirium Zero Protocol to Prevent the Onset of Delirium in Patients Undergoing Hip Fracture Surgery: Randomized Clinical Trial

Recruiting·Cardenal Herrera University·Preclinical·NCT07202208·112 enrolled

Comparative Study Between Pericapsular Nerve Group Block (PENG) And Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block for Positioning Analgesia Prior to Spinal Anesthesia in Hip Fracture Patients

Recruiting·AAin Shams University·Preclinical·NCT07687290·24 enrolled

The Effects of Intravenous Iron on Mobility in Elderly Patients Following Hip Fracture Surgery

Recruiting·—·Phase 4·NCT06898814·210 enrolled

PENG vs Femoral Block for Hip Fracture Analgesia

Recruiting·WWeill Medical College of Cornell University·N/A·NCT07073209·352 enrolled

Effect of Early Administration of TXA in Adult Hip Fractures

Recruiting·AAscension Health·Phase 2/3·NCT05047133·170 enrolled

One Versus Two Doses of Tranexamic Acid in Surgically Treated Extracapsular Hip Fractures

Recruiting·—·N/A·NCT07432737·120 enrolled

Iliopsoas Nerve Block and Femoral Nerve Block in Hip Fracture Surgeries

Recruiting·—·N/A·NCT06852378·80 enrolled

Emergency Physician-performed Ultrasound-guided Femoral Nerve Blocks in Patients With Hip Fractures.

Recruiting·NNational Taiwan University Hospital·N/A·NCT05969561·80 enrolled

Feasibility, Fidelity, and Acceptability of a Co-designed Intervention to Promote Mobility in Patients After Hip Fracture Surgery

Active, not recruiting·HHvidovre University Hospital·Preclinical·NCT07561164·25 enrolled

Artificial Intelligence-Based Analysis of Risk Factors and Risk Prediction Model for Major Adverse Cardiovascular Events Following Hip Fracture Surgery in the Elderly

Active, not recruiting·BBeijing Anzhen Hospital·N/A·NCT07709377·600 enrolled

A Randomized Controlled Trial on A Decision Support Tool for Common Surgical Fixations of Hip Fractures

Not yet recruiting·TTaipei Medical University WanFang Hospital·Preclinical·NCT07909876·450 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)