VivoSeq
Other

Hyperalgesia

0

Pipeline Programs↗

0

Active Trials↗

4

Companies Involved↗

Hyperalgesia is an early-stage landscape with 0 programs across 4 companies. The most active players are GSK, Biogen, TorreyPines Therapeutics.

Intelligence

Pipeline Metrics

Competitive Density

0/100

Pipeline Velocity

0/100

Mech. Concentration

N/A

Completion Rate

85/100

Attrition Rate

12/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

GSK logo

GSK

0 programs

PreclinicalBiogen logo

Biogen

0 programs

PreclinicalT

TorreyPines Therapeutics

0 programs

PreclinicalA

Abide Therapeutics

0 programs

Preclinical

Pipeline

Programs by Phase

No pipeline programs currently tracked for this disease.

Analysis

Trial Status

42

clinical trials

Completed28 · 67%
Unknown status9 · 21%
Terminated4 · 10%
Withdrawn1 · 2%

Clinical Trials

Trial Activity

42 trials

Effects of Lidocaine Patch on Intradermal Capsaicin Induced Pain and Hyperalgesia
Completed·UUniversity of California, San Diego·Phase 1·NCT00373893·12 enrolled
Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen
Completed·SSeoul National University Hospital·N/A·NCT02243254·120 enrolled
A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers
Completed·GSK logoGSK·Phase 1·NCT00387413·40 enrolled
Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia
Completed·FFederal University of São Paulo·Phase 3·NCT01301079·60 enrolled
Effect of Oral Rufinamide and Oxcarbazepine on Nerve Excitability, Hyperalgesia, Allodynia and Flare Reaction Compared to Placebo. A Monocenter, Randomized, Double-blind, Cross-over Study
Completed·UUniversity of Zurich·N/A·NCT01212458·24 enrolled
The Effect of Remimazolam on Opioid Induced Hyperalgesia
Completed·WWonkwang University Hospital·N/A·NCT05866315·108 enrolled
Effect of High Dose Naloxone on Secondary Hyperalgesia
Completed·—·Phase 1·NCT01935206·15 enrolled
Mechanisms of Sleep Disruption Hyperalgesia
Completed·JJohns Hopkins University·N/A·NCT01794689·100 enrolled
Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil
Completed·JJohns Hopkins University·N/A·NCT00991809·22 enrolled
Opiate-Induced Tolerance & Hyperalgesia in Pain Patients
Completed·National Institute of General Medical Sciences (NIGMS)·Phase 4·NCT00246532·139 enrolled
Hyperalgesia and Pain
Completed·AAir Liquide Santé International·Phase 1·NCT01581450·20 enrolled
Remifentanil and Hyperalgesia: Gradual Withdrawal Versus Immediate Discontinuation
Completed·UUniversité Libre de Bruxelles·N/A·NCT03110653·30 enrolled
A Safety Tolerance and Experimental Hyperalgesia Study of Oral NGX426 in Healthy Male Voluneteers
Completed·TTorreyPines Therapeutics·Phase 1·NCT00832546·18 enrolled
The Effect of Ultra-low-dose Naloxone on Remifentanil-induced Postoperative Hyperalgesia - A Randomized Controlled Study
Completed·SSeoul National University Hospital·N/A·NCT02856087·92 enrolled
Modulation of Remifentanil-induced Postinfusion Hyperalgesia
Completed·UUllevaal University Hospital·Phase 4·NCT00785863·16 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)