Alfenta
(alfentanil)ApprovedSmall molecule
Alnylam PharmaceuticalsAlfentanil is a powerful painkiller used during surgery and medical procedures to manage pain and help keep patients comfortable. It works quickly in the body and is often used alongside anesthesia during operations.[2] Alfenta is currently approved and in use across 8 indications[4].[1]
Alfenta is one of 155 small molecule programs targeting Hip Fracture. It is currently in Approved.
8
Indications
31
Total Trials
1
Active Trials
154
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
Pipeline
Status by Indication[4][1]
Indication
Competition
Competitive Landscape
686 competitors in Lung Cancer
#DrugCompanyPhaseTrials
1Alfenta
Alnylam PharmaceuticalsApproved
Tecentriq
RochePreclinical
Libtayo
RegeneronPreclinical
Vizimpro
PfizerPreclinical
Talzenna
PfizerPreclinical
Folvite
Eli LillyPreclinical
Xylocaine
MMEDRx USA, Inc.
Preclinical
Immunotherapy
Bristol-Myers SquibbPreclinical
Paclitaxel and Carboplatin
Bristol-Myers SquibbPreclinical
Rilotumumab
AmgenPreclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Clinical
Trials by Indication[1]
Sedation5 trials
Can we Get Conscious Sedation by Combining Dexmedetomidine With Alfentanil?
Completed·CCliniques universitaires Saint-Luc- Université Catholique de Louvain·Phase 4·NCT02358057·40 enrolled
Analgesia2 trials
Nausea and vomiting1 trial
21 more indications
Laryngeal Mask Airway1 trial
Anesthesia1 trial
Bronchoscopy1 trial
Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
Completed·—·Phase 4·NCT01470170·173 enrolled
Lung Cancer1 trial
Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic
Completed·—·Phase 4·NCT00440960
Surgery1 trial
To Explore the Optimal Dose of Alfentanil for Skull Pin Fixation in Intracranial Surgery
Not yet recruiting·KKaohsiung Medical University Chung-Ho Memorial Hospital·Phase 4·NCT06563297·40 enrolled
Anesthesia Induction1 trial
Remifentanil1 trial
Hip Fracture1 trial
Unspecified1 trial
Regulatory
FDA Approval Timeline[5]
Dec 29, 1986
ALFENTA
NDA NDA019353
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Alfenta drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for alfentanil. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]
Details
Drug Info
Quick Facts
- Mechanism of Action
- Mu Opioid Receptor Agonist[3]
- Modality
- Small molecule[3]
- Highest Phase
- Approved[1]
- Company