Alfenta
(alfentanil)ApprovedSmall molecule
Jazz PharmaceuticalsAlfentanil is a powerful painkiller used during surgery and medical procedures to manage pain and help keep patients comfortable. It works quickly in the body and is often used alongside anesthesia during operations.[2] Alfenta is currently approved and in use across 16 indications[4].[1]
Alfenta is one of 233 small molecule programs targeting Nephrolithiasis. It is currently in Approved.
16
Indications
33
Total Trials
2
Active Trials
232
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
Pipeline
Status by Indication[4][1]
Indication
Showing 10 of 13 indications
Competition
Competitive Landscape
350 competitors in Treatment
#DrugCompanyPhaseTrials
1Alfenta
Jazz PharmaceuticalsApproved
Dexilant
TakedaPreclinical
Niclocide
BayerPreclinical
Hivid
CConrado Roberto Hoffmann Filho
Preclinical
Valium
Akero TherapeuticsPreclinical
Lotemax
PPharmos
Preclinical
Norpramin
VValidus Pharmaceuticals
Preclinical
Barhemsys
Tibotec Pharmaceuticals, IrelandPreclinical
Clomid
FerringPreclinical
Aurlumyn
BBTG International Inc.
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Sedation5 trials
Can we Get Conscious Sedation by Combining Dexmedetomidine With Alfentanil?
Completed·CCliniques universitaires Saint-Luc- Université Catholique de Louvain·Phase 4·NCT02358057·40 enrolled
Analgesia2 trials
Bronchoscopy1 trial
Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
Completed·—·Phase 4·NCT01470170·173 enrolled
23 more indications
Hyperalgesia1 trial
Surgery1 trial
To Explore the Optimal Dose of Alfentanil for Skull Pin Fixation in Intracranial Surgery
Not yet recruiting·KKaohsiung Medical University Chung-Ho Memorial Hospital·Phase 4·NCT06563297·40 enrolled
Anesthesia Induction1 trial
Remifentanil1 trial
Nausea and vomiting1 trial
Laryngeal Mask Airway1 trial
Lung Cancer1 trial
Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic
Completed·—·Phase 4·NCT00440960
Anesthesia1 trial
Hip Fracture1 trial
Recovery Period1 trial
Hemodynamic Instability1 trial
Unspecified1 trial
Regulatory
FDA Approval Timeline[5]
Dec 29, 1986
ALFENTA
NDA NDA019353
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Alfenta drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for alfentanil. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]
Details
Drug Info
Quick Facts
- Mechanism of Action
- Mu Opioid Receptor Agonist[3]
- Modality
- Small molecule[3]
- Highest Phase
- Approved[1]
- Company