VivoSeq
Metabolic & Endocrine

Hypothyroidism

35

Pipeline Programs

13

Active Trials

16

Companies Involved

Hypothyroidism is a moderately active landscape with 35 programs across 16 companies. The most active players are AstraZeneca, Sention Therapeutics, LLC, Pascoe Pharmazeutische Praeparate GmbH. 15 therapies are approved with 2 more in late-stage development.

Pipeline Metrics

Competitive Density

56/100

Pipeline Velocity

6/100

Mech. Concentration

50/100

Completion Rate

82/100

Attrition Rate

10/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Trial Status

59

clinical trials

Completed28 · 47%
Unknown status12 · 20%
Recruiting9 · 15%
Withdrawn4 · 7%
Not yet recruiting3 · 5%
Terminated2 · 3%
Other1 · 2%

Trial Activity

59 trials

Novel Approaches to the Treatment of Hypothyroidism
Recruiting·UUConn Health·Phase 2/3·NCT06731764·90 enrolled
T4/T3 Therapy in Hypothyroidism
Not yet recruiting·UUniversity of Pennsylvania·Phase 2·NCT07424183·60 enrolled
A Study of T3 Therapy in Patients With Hypothyroidism
Completed·IIpe, LLC·Phase 2·NCT01800617·18 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)