VivoSeq
Other

Impaired Glucose Tolerance

27

Pipeline Programs↗

3

Active Trials↗

17

Companies Involved↗

Impaired glucose tolerance is an emerging landscape with 27 programs across 17 companies. The most active players are Limerick BioPharma, Haisco Pharmaceutical Group Co., Ltd., Arete Therapeutics. 6 therapies are approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

51/100

Pipeline Velocity

0/100

Mech. Concentration

20/100

Completion Rate

81/100

Attrition Rate

14/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

L

Limerick BioPharma

1 program

Phase 2Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.

1 program

Phase 2A

Arete Therapeutics

1 program

Phase 2Boehringer Ingelheim logo

Boehringer Ingelheim

1 program

Phase 2Z

Zydus Therapeutics Inc.

1 program

Phase 2C

Cantex Pharmaceuticals

1 program

Phase 2

Pipeline

Programs by Phase

Analysis

Modality Breakdown

97%

Small molecule

33 of 34 classified programs — the dominant modality here.

3%ALL OTHERSMonoclonal antibody13%

Small molecule leads; the ring shows all 34 classified programs, each share of the total. Modality classified for 100% of 34 pipeline programs.

Analysis

Trial Status

37

clinical trials

Completed22 · 59%
Unknown status7 · 19%
Withdrawn4 · 11%
Recruiting2 · 5%
Not yet recruiting1 · 3%
Terminated1 · 3%

Clinical Trials

Trial Activity

37 trials

Efficacy and Safety of Sanggua Tablets in the Treatment of Patients With Impaired Glucose Tolerance and Mild Type 2 Diabetes
Recruiting·TTongji Hospital·Phase 1·NCT06964620·84 enrolled
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
Recruiting·TThe University of Texas Health Science Center at San Antonio·N/A·NCT02969798·700 enrolled
Preliminary Safety and Efficacy Study of Extracellular Vesicle Infusion in the Intervention of Age-related Phenotypes With Impaired Glucose Tolerance.
Not yet recruiting·BBEAUTECH·N/A·NCT06495437·20 enrolled
Treatment of Impaired Glucose Tolerance in Pregnancy
Completed·—·N/A·NCT00625781·72 enrolled
Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance
Completed·UUniversity of Guadalajara·Phase 2·NCT02621060·30 enrolled
A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects
Completed·Boehringer Ingelheim logoBoehringer Ingelheim·Phase 2·NCT01248364·91 enrolled
Japan Prevention Trial of Diabetes by Pitavastatin in Patients With Impaired Glucose Tolerance (J-PREDICT)
Completed·TTokyo University·Phase 4·NCT00301392·1,240 enrolled
HSK7653 in Chinese Patients with Impaired Glucose Tolerance
Completed·Haisco Pharmaceutical Group Co., Ltd. logoHaisco Pharmaceutical Group Co., Ltd.·Phase 2·NCT04727580·99 enrolled
Voglibose Tablets 0.2 / OD Tablets 0.2 Special Drug Use Surveillance "Long-term Use in Patients With Impaired Glucose Tolerance"
Completed·Takeda logoTakeda·N/A·NCT01993927·742 enrolled
The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting Glucose
Completed·FForest Laboratories·Phase 4·NCT00673790·537 enrolled
To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies
Completed·Novartis logoNovartis·Phase 2·NCT01068860·246 enrolled
Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance.
Completed·UUniversity of Guadalajara·Phase 2·NCT02708966·30 enrolled
Clinical Trial of Efficacy and Safety of Subetta in the Treatment of Impaired Glucose Tolerance
Completed·MMateria Medica Holding·Phase 3·NCT03725033·538 enrolled
Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance
Completed·—·N/A·NCT01375959·38 enrolled
Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth
Completed·YYale University·N/A·NCT00413335·21 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)