VivoSeq
Other

Infertility

97

Pipeline Programs↗

24

Active Trials↗

34

Companies Involved↗

Infertility is a moderately active landscape with 97 programs across 34 companies. The most active players are Sclnow Biotechnology Co., Ltd., Azurity Pharmaceuticals, Eastern Cooperative Oncology Group. 38 therapies are approved with 23 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

70/100

Pipeline Velocity

37/100

Mech. Concentration

9/100

Completion Rate

76/100

Attrition Rate

9/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

S

Sclnow Biotechnology Co., Ltd.

1 program

Phase 1A

Azurity Pharmaceuticals

1 program

Phase 2E

Eastern Cooperative Oncology Group

1 program

Phase 2Boehringer Ingelheim logo

Boehringer Ingelheim

1 program

Phase 2GSK logo

GSK

2 programs

Phase 2Merck & Co. logo

Merck & Co.

3 programs

Phase 3

Pipeline

Programs by Phase

Preclinical17

Clomiphene Citrate

Ferring

Levonorgestrel

Italian Network for Tumor Biotherapy Foundation

Ergocalciferol

Alnylam Pharmaceuticals

Ulipristal Acetate

AbbVie

Corifollitropin Alfa

Organon and Co

Phase 12

Zinc Sulfate

Fakultas Kedokteran Universitas Indonesia

AD-SVF

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase 217

Cabergoline

Pfizer

Nimodipine

Azurity Pharmaceuticals

Filgrastim

Eastern Cooperative Oncology Group

Metformin Hydrochloride

Boehringer Ingelheim

Somatropin

EMD Serono

Phase 323

Goserelin Acetate

AstraZeneca

Orlistat

Engelhard Arzneimittel GmbH & Co.KG

Medroxyprogesterone Acetate

Eli Lilly

Follitropin Alfa

EMD Serono

Simethicone

Portuguese Oncology Institute, Coimbra

Approved38

Coenzyme Q10

Mclean Hospital

Progesterone

Ferring

Ganirelix

Organon and Co

Isotretinoin

Conrado Roberto Hoffmann Filho

Estradiol

Novo Nordisk

Analysis

Modality Breakdown

96%

Small molecule

105 of 109 classified programs — the dominant modality here.

4%ALL OTHERSCell therapy22%Protein / enzyme1<1%Peptide1<1%

Small molecule leads; the ring shows all 109 classified programs, each share of the total. Modality classified for 97% of 122 pipeline programs.

Analysis

Trial Status

86

clinical trials

Completed31 · 36%
Unknown status21 · 24%
Recruiting14 · 16%
Not yet recruiting6 · 7%
Terminated5 · 6%
Withdrawn3 · 3%
Other6 · 7%

Clinical Trials

Trial Activity

86 trials

Possible Action of Resveratrol in Improving the Outcomes of IVF/ICSI in Couples With Unexplained Infertility
Recruiting·AAndros Day Surgery Clinic·N/A·NCT06481696·90 enrolled
Autologous Decidual-like Natural Killer Cells Therapy for Infertility or Adverse Pregnancy History
Recruiting·TThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School·Phase 1·NCT06821685·14 enrolled
Uterus Transplantation to Treat Infertility
Recruiting·JJohns Hopkins University·Phase 2/3·NCT05646992·40 enrolled
AD-SVF Therapy for Refractory Endometrial Infertility
Recruiting·TThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School·Phase 1·NCT07230600·10 enrolled
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
Recruiting·GGranata Bio Corporation·Phase 3·NCT07216742·659 enrolled
CRD vs. Met in Patients With Obese PCOS Infertility
Recruiting·SShanghai First Maternity and Infant Hospital·N/A·NCT06049186·406 enrolled
GnRH for Luteal Support in IVF/ICSI/FET Cycles
Recruiting·UUniversity Reproductive Associates·Approved·NCT02357654·350 enrolled
Correlation Between Endometrial Peristalsis And Pregnancy Outcomes In Patients Undergoing Frozen Embryo Transfer With Hormone Replacement Therapy for Endometrial Preparation Protocol
Recruiting·MMỹ Đức Hospital·N/A·NCT07675213·442 enrolled
Food & Fertility - Does Food Intake Affect Your Fertility?
Recruiting·AAalborg University Hospital·N/A·NCT05454046·4,000 enrolled
Automation of the In Vitro Fertilization Laboratory: A Validation Study
Recruiting·CConceivable Life Sciences·Preclinical·NCT06581068·150 enrolled
Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF)
Recruiting·BBrigham and Women's Hospital·Preclinical·NCT04026893·250 enrolled
Clinical Validation of Ultra-rapid Blastocyst Vitrification: a Randomized Pilot Study in Oocyte Donation Cycles
Recruiting·FFundacion Dexeus·Preclinical·NCT07556601·80 enrolled
Impact of Hyaluronan-enriched Medium on Pregnancy Outcomes Following Euploid Blastocyst Transfers
Recruiting·AART Fertility Clinics LLC·Preclinical·NCT06165367·783 enrolled
IntelliWell: An AI-Assisted Microwell Platform for Label-Free Localization of Ultra-Rare Sperm in Non-Obstructive Azoospermia Micro-TESE Specimens
Recruiting·BBrigham and Women's Hospital·Preclinical·NCT07074015·20 enrolled
FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea
Active, not recruiting·YYale University·Phase 3·NCT05364008·33 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)