VivoSeq
Other

Liver Failure

12

Pipeline Programs

3

Active Trials

9

Companies Involved

Liver Failure is an emerging landscape with 12 programs across 9 companies. The most active players are Takeda, AstraZeneca, Johnson & Johnson. 5 therapies are approved with 2 more in late-stage development.

Pipeline Metrics

Competitive Density

40/100

Pipeline Velocity

11/100

Mech. Concentration

13/100

Completion Rate

50/100

Attrition Rate

23/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

87%

Small molecule

13 of 15 classified programs — the dominant modality here.

13%ALL OTHERSCell therapy213%

Small molecule leads; the ring shows all 15 classified programs, each share of the total. Modality classified for 100% of 18 pipeline programs.

Trial Status

13

clinical trials

Unknown status4 · 31%
Completed3 · 23%
Withdrawn2 · 15%
Recruiting2 · 15%
Not yet recruiting1 · 8%
Terminated1 · 8%

Trial Activity

13 trials

Safety and Efficacy of Human Mesenchymal Stem Cells for Treatment of Liver Failure
Unknown status··Phase 1/2·NCT01218464·70 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)