VivoSeq
Oncology

Locally Advanced Breast Cancer

10

Pipeline Programs↗

3

Active Trials↗

7

Companies Involved↗

Locally Advanced Breast Cancer is an early-stage landscape with 10 programs across 7 companies. The most active players are Sun Pharma Advanced Research Company Limited, Avyxa, Johnson & Johnson.

Intelligence

Pipeline Metrics

Competitive Density

38/100

Pipeline Velocity

6/100

Mech. Concentration

67/100

Completion Rate

N/A

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Sun Pharma Advanced Research Company Limited logo

Sun Pharma Advanced Research Company Limited

1 program

Phase 2A

Avyxa

1 program

Phase 2Johnson & Johnson logo

Johnson & Johnson

1 program

Phase 2Teva logo

Teva

1 program

Phase 2Eisai logo

Eisai

1 program

Phase 2BioNTech logo

BioNTech

6 programs

Phase 2

Pipeline

Programs by Phase

Analysis

Trial Status

3

clinical trials

Recruiting2 · 67%
Active, not recruiting1 · 33%

Clinical Trials

Trial Activity

A Non-interventional Study to Evaluate the Effectiveness and Safety of Inavolisib in Patients With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer (reaINAVO)
Recruiting·Roche logoRoche·N/A·NCT07347600·500 enrolled
A Phase II, Multi-site, Randomized, Open-label Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of BNT327 at Two Dose Levels in Combination With Chemotherapeutic Agents as First- and Second-line Treatment in Triple-negative Breast Cancer
Active, not recruiting·BioNTech logoBioNTech·Phase 2·NCT06449222·83 enrolled
A Phase I/II, Multi-site, Open-label, Two-part Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of BNT323 in Combination With BNT327 in Participants With Advanced Breast Cancer
Recruiting·BioNTech logoBioNTech·Preclinical·NCT06827236·380 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)