VivoSeq
Other

Neonatal

3

Pipeline Programs↗

12

Active Trials↗

5

Companies Involved↗

Neonatal is an early-stage landscape with 3 programs across 5 companies. The most active players are Johnson & Johnson, Argenx, Eli Lilly. 3 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

34/100

Pipeline Velocity

27/100

Mech. Concentration

50/100

Completion Rate

93/100

Attrition Rate

3/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Johnson & Johnson logo

Johnson & Johnson

1 program

Phase 3Argenx logo

Argenx

1 program

Phase 3Eli Lilly logo

Eli Lilly

1 program

Phase 3Chiesi Farmaceutici S.p.A. logo

Chiesi Farmaceutici S.p.A.

0 programs

PreclinicalS

Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 33

Nipocalimab

Johnson & Johnson

Ivig

Argenx

Prednisone

Roxane Laboratories

Approved
No programs

Analysis

Modality Breakdown

67%

Small molecule

2 of 3 classified programs — the dominant modality here.

33%ALL OTHERSMonoclonal antibody133%

Small molecule leads; the ring shows all 3 classified programs, each share of the total. Modality classified for 75% of 4 pipeline programs.

Analysis

Trial Status

31

clinical trials

Completed14 · 45%
Recruiting8 · 26%
Unknown status4 · 13%
Not yet recruiting3 · 10%
Withdrawn1 · 3%
Enrolling by invitation1 · 3%

Clinical Trials

Trial Activity

31 trials

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations
Recruiting·SShandong University·N/A·NCT06076200·50 enrolled
Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome
Recruiting·JJohns Hopkins University·Phase 1·NCT06283355·175 enrolled
The Caffeine Therapy in the Fetal to Neonatal Transition
Recruiting·HHospital de Clinicas de Porto Alegre·Phase 4·NCT05454332·50 enrolled
Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation
Recruiting·UUniversity of Alberta·Phase 1·NCT05738148·20 enrolled
Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS
Recruiting·—·Phase 1·NCT06367881·60 enrolled
deMISTify: The Impact of CPAP Levels During Minimally Invasive Surfactant Therapy on Regional Patterns of Ventilation in Preterm Infants
Recruiting·MMurdoch Childrens Research Institute·Preclinical·NCT07522346·36 enrolled
Double-blind, Randomized, Placebo-controlled Study Evaluating the Safety and Efficacy of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) in At-risk Pregnancies
Recruiting·Johnson & Johnson logoJohnson & Johnson·Phase 3·NCT06449651·39 enrolled
Multicenter, Open-Label, Randomized Study of Nipocalimab or IVIG in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
Recruiting·Johnson & Johnson logoJohnson & Johnson·Phase 3·NCT06533098·50 enrolled
Caffeine Citrate to Improve Neonatal Outcomes.
Not yet recruiting·UUniversity of Melbourne·N/A·NCT06972849·3,900 enrolled
Predictors of Rebound Hyperbilirubinemia After Phototherapy in Neonates
Not yet recruiting·HHaseki Training and Research Hospital·N/A·NCT07694635·300 enrolled
Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE Trial
Not yet recruiting·UUniversity Medical Center Groningen·Preclinical·NCT07674537·680 enrolled
The Effect of the Hat-Type Glasses Intervention Used in Phototherapy on Phototherapy Stay Duration, Comfort Level, and Parental Satisfaction
Enrolling by invitation·KKaramanoğlu Mehmetbey University·Preclinical·NCT07690930·24 enrolled
Oral Sweet Solution to Prevent Pain During Neonatal Hip Examination
Completed·—·N/A·NCT03486015·100 enrolled
Neonatal Phase 1 Valacyclovir Study
Completed·National Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT05468619·17 enrolled
N-Acetylcysteine in Neonatal Congenital Heart Surgery (INACT Study)
Completed·UUniversity of Michigan·Phase 2·NCT00374088·21 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)