immunoglobulins

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

COVID-19Neonatal

317 competitors in COVID-19

#DrugCompanyPhaseTrials

1

immunoglobulins

CSL Behring

Phase 3

12

Blood Taken

HHospices Civils de Lyon

Preclinical

13

Other Tkis

Bayer

Preclinical

14

Serology

UUniversity Hospital Center of Martinique

Preclinical

35

Pfizer-Biontech COVID-19 MRNA Vaccine

Pfizer

Preclinical

16

Thrombolytic

FFaculty Hospital Kralovske Vinohrady

Preclinical

17

Administration of Almitrine

CCentre Hospitalier Universitaire de Nice

Preclinical

18

Tpa

UUniversity of Florida

Preclinical

19

Serological Test

CCentre Hospitalier de Cornouaille

Preclinical

210

Coronavac COVID-19 Vaccine

HHospital Moinhos de Vento

Preclinical

2Show 5 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Primary Immunodeficiencies3 trials

Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)

Completed·CSL Behring·Phase 3·NCT00168025·89 enrolled

Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID)

Completed·CSL Behring·Phase 3·NCT00168012·42 enrolled

Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)

Completed·CSL Behring·Phase 3·NCT00322556·55 enrolled

Prevention2 trials

Anti-HIV Immunoglobulin (HIVIG) in Prevention of Maternal-Fetal HIV Transmission (Pediatric ACTG Protocol 185)

Completed·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 3·NCT00000590

Transfusion-Transmitted Cytomegalovirus Prevention in Neonates

Completed·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 3·NCT00000584

Chronic Inflammatory Demyelinating Polyneuropathy1 trial

Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Recruiting·UUniversity of Ulm·Phase 2·NCT04881682·20 enrolled

CIDP1 trial

Immunoglobulin Dosage and Administration Form in CIDP and MMN

Completed·RRigshospitalet, Denmark··NCT02111590·36 enrolled

Encephalitis1 trial

Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis

Completed·UUniversity of Oxford·Phase 3·NCT02308982·18 enrolled

16 more indications

Cardiomyopathy1 trial

Intravenous Immunoglobulin (IVIg) for Parvovirus B19(PVB19) Mediated Cardiomyopathy

Completed·PProthya Biosolutions·Phase 3·NCT00892112·50 enrolled

Dexamethasone1 trial

IgIV Plus Prednisone vs High-dose Dexamethasone for ITP

Recruiting·AAssistance Publique - Hôpitaux de Paris·Phase 3·NCT04968899·272 enrolled

Aneurysm1 trial

Prevention of Coronary Aneurysms in Kawasaki Syndrome

Completed·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 2·NCT00000520

Pediatric Heart Transplantation1 trial

Alloantibodies in Pediatric Heart Transplantation

Terminated·NNational Institute of Allergy and Infectious Diseases (NIAID)··NCT01005316·290 enrolled

Post-Polio Syndrome1 trial

Intravenous Immunoglobulins for Post-Polio Syndrome

Completed·AAzienda Ospedaliera Universitaria Integrata Verona·Phase 3·NCT01537575·50 enrolled

Urticaria1 trial

Intravenous Immunoglobulins in Severe and Refractory Solar Urticaria

Completed·—·Phase 2·NCT01360658·10 enrolled

Hepatitis B1 trial

Interruption of Maternal-to-Infant Transmission of Hepatitis B by Means of Hepatitis B Immune Globulin

Completed·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 3·NCT00000580

Renal Transplant Recipients1 trial

Immunoregulatory Effects of Immunoglobulin Induction Therapy in Renal Transplant Recipients

Completed·UUniversity of Giessen·Phase 1·NCT00176059·50 enrolled

Intravenous1 trial

Intravenous Immunoglobulins in Complex-regional Pain Syndrome

Withdrawn·UUniversity of Giessen·Phase 3·NCT00949065

Myasthenia Gravis1 trial

Subcutaneous Ig Maintenance Therapy for Myasthenia Gravis

Terminated·SSt. Louis University·Phase 1·NCT01828294·4 enrolled

Antibody Response1 trial

Treatment of Deficient Subclass or Anti-polysaccharide Antibody Response

Completed·PProthya Biosolutions·Phase 4·NCT00522821·55 enrolled

Vasculitis1 trial

Intravenous Immunoglobulin After Relapse in Vasculitis

Terminated·AAssistance Publique - Hôpitaux de Paris·Phase 3·NCT00307658·40 enrolled

Antibiotic Therapy1 trial

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension

Recruiting·MMonash University·Phase 2/3·NCT05678621·300 enrolled

COVID-191 trial

Intravenous Immunoglobulin Replacement Therapy for Persistent COVID-19 in Patients With B-cell Impairment

Recruiting·JJaehoon Ko·Phase 2·NCT06159283·58 enrolled

Neonatal1 trial

Multicenter, Open-Label, Randomized Study of Nipocalimab or IVIG in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Recruiting·Johnson & Johnson·Phase 3·NCT06533098·50 enrolled

Kidney1 trial

Intravenous Immunoglobulins for Prevention of BKV Infection in Kidney Transplant Recipients According to BKV Genotype-specific Neutralizing Antibody Titers at the Day of Transplantation: A Multicenter Study

Completed·UUniversity Hospital, Strasbourg, France·Approved·NCT04222023·359 enrolled

Details

Drug Info

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