VivoSeq
Other

Neuroma

11

Pipeline Programs↗

2

Active Trials↗

9

Companies Involved↗

Neuroma is an emerging landscape with 11 programs across 9 companies. The most active players are AstraZeneca, Sorrento Therapeutics, Inc., AlgoRx Pharmaceuticals. 2 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

38/100

Pipeline Velocity

6/100

Mech. Concentration

25/100

Completion Rate

83/100

Attrition Rate

13/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

AstraZeneca logo

AstraZeneca

1 program

Phase 1S

Sorrento Therapeutics, Inc.

1 program

Phase 1A

AlgoRx Pharmaceuticals

1 program

Phase 2V

Vitae Pharmaceuticals Inc., an Allergan affiliate

1 program

Phase 2C

Centrexion Therapeutics

2 programs

Phase 2A

Averitas Pharma, Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

16

clinical trials

Completed10 · 63%
Unknown status2 · 13%
Withdrawn2 · 13%
Recruiting1 · 6%
Not yet recruiting1 · 6%

Clinical Trials

Trial Activity

16 trials

Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain
Recruiting·National Institutes of Health Clinical Center (CC)·Phase 1·NCT05695339·24 enrolled
Silencing Neuroma Pain-Botulinum Toxin Versus Local Anesthetic Injection
Not yet recruiting·CCharitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)·N/A·NCT07431944·100 enrolled
Morton's Neuroma: Manipulation Versus Steroid Injection
Completed·DDundee Podiatry Clinic·N/A·NCT05707572·62 enrolled
Ultrasound-Guided Radiofrequency Ablation Versus Steroid Injection for Stump Neuroma
Completed·GGaziler Physical Medicine and Rehabilitation Education and Research Hospital·N/A·NCT07431424·26 enrolled
Lidocaine and Neuroma Pain Related Modalities
Completed·UUppsala University·N/A·NCT02300038·16 enrolled
Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma
Completed·IIcahn School of Medicine at Mount Sinai·Phase 1·NCT02838758·10 enrolled
Neuromas as the Cause of Pain
Completed·—·N/A·NCT02930551·12 enrolled
ALGRX 4975 in the Treatment of Patients With Morton's Neuroma
Completed·AAlgoRx Pharmaceuticals·Phase 2·NCT00130962·60 enrolled
Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Completed·CCentrexion Therapeutics·Phase 1·NCT02550756·11 enrolled
A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Completed·CCentrexion Therapeutics·Phase 2·NCT02678793·67 enrolled
A Study to Evaluate the Efficacy and Safety of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Completed·CCentrexion Therapeutics·Phase 2·NCT02283957·119 enrolled
A Study to Characterize the Phenotype in Patients With Morton's Neuroma and to Explore the Effect of Local Administration of Xylocaine (Lidocaine)
Completed·AstraZeneca logoAstraZeneca·Phase 1·NCT01298310·27 enrolled
Botulinum Toxin Type A for Neuroma Pain
Withdrawn·SSouthern Illinois University·Phase 2·NCT01374191
Evaluation of Neuroma Perfusion with Indocyanine Green Fluorescence Angiography
Withdrawn·NNorthwestern University·Phase 4·NCT06164392
Morton's Neuroma: Manipulation Versus Steroid Injection
Unknown status·—·N/A·NCT02304094·64 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)