VivoSeq
Psychiatry

Opioid Use

1

Pipeline Programs↗

5

Active Trials↗

5

Companies Involved↗

Opioid Use is an early-stage landscape with 1 program across 5 companies. The most active players are TO Pharmaceuticals, Nektar Therapeutics, AstraZeneca.

Intelligence

Pipeline Metrics

Competitive Density

22/100

Pipeline Velocity

11/100

Mech. Concentration

N/A

Completion Rate

71/100

Attrition Rate

19/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

T

TO Pharmaceuticals

1 program

PreclinicalN

Nektar Therapeutics

0 programs

PreclinicalAstraZeneca logo

AstraZeneca

0 programs

PreclinicalPfizer logo

Pfizer

0 programs

PreclinicalB

Brittany Miller-Roenigk

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical1

Cannabis

TO Pharmaceuticals

Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved
No programs

Analysis

Trial Status

21

clinical trials

Completed10 · 48%
Recruiting4 · 19%
Terminated2 · 10%
Unknown status2 · 10%
Withdrawn2 · 10%
Not yet recruiting1 · 5%

Clinical Trials

Trial Activity

21 trials

Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children
Recruiting·UUniversity of California, Davis·Phase 2/3·NCT04724252·60 enrolled
Opioid Use Post-Discharge After Ambulatory Distal Arm Surgery
Recruiting·UUniversity Health Network, Toronto·N/A·NCT04044820·292 enrolled
Efficacy of a Pill-Dispensing System to Increase Disposal of Unused Opioids and to Reduce Refills After Cancer-Related Surgery
Recruiting·CColumbia University·Preclinical·NCT05585788·140 enrolled
Leveraging mHealth to Promote Recovery From Opioid Use Disorder and Commonly Occurring Mental Health Disorders Among Residents of a Medium-Sized Midwestern City
Recruiting·WWashington University School of Medicine·Phase 2·NCT07673380·300 enrolled
Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use
Not yet recruiting·—·Phase 1·NCT07218549·72 enrolled
Prevention of Persistent Opioid Use in Mothers
Completed·SStanford University·Phase 4·NCT03472521·78 enrolled
Impact of Lofexidine on Stress, Craving and Opioid Use
Completed·MMedical University of South Carolina·Phase 2·NCT03718065·112 enrolled
A Study to Assess the Effect of AZD4041 on Respiratory Drive in Recreational Opioid Users.
Completed·AstraZeneca logoAstraZeneca·Phase 1·NCT05587998·45 enrolled
Reducing Pain and Opioid Use With CBD
Completed·UUniversity of Colorado, Denver·Phase 2·NCT05299944·126 enrolled
A Study of the Abuse Liability Potential of ALKS 5461 in Healthy, Non-Dependent, Recreational Opioid Users
Completed·AAlkermes, Inc.·Phase 1·NCT02413281·56 enrolled
A Study to Characterize the Abuse Liability of ALO-02 in Healthy, Non-Dependent, Recreational Opioid Users When ALO-02 Capsules Are Crushed and Snorted
Completed·Pfizer logoPfizer·Phase 1·NCT01775189·45 enrolled
A Study of the Abuse Liability Potential of Samidorphan in Healthy, Non-Dependent, Recreational Opioid Users
Completed·AAlkermes, Inc.·Phase 1·NCT02218021·59 enrolled
Development and Implementation of a Culturally Centered Opioid Prevention Intervention for American Indian/Alaska Native Young Adults in California
Completed·RRAND·Preclinical·NCT04617938·541 enrolled
Culturally AdapTed Harm Reduction Intervention: Community Engaged InterVention for Black Adults That MisusE Opioids and Stimulants
Completed·—·Preclinical·NCT06609278·63 enrolled
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
Completed·MMassachusetts General Hospital·Preclinical·NCT04827992·87 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)