VivoSeq
Neurology

Parkinson Disease

152

Pipeline Programs

44

Active Trials

70

Companies Involved

Parkinson disease is a highly competitive landscape with 152 programs across 70 companies. The most active players are ACADIA Pharmaceuticals Inc., Avid Radiopharmaceuticals, Biogen. 63 therapies are approved with 13 more in late-stage development.

Pipeline Metrics

Competitive Density

77/100

Pipeline Velocity

42/100

Mech. Concentration

5/100

Completion Rate

84/100

Attrition Rate

9/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

95%

Small molecule

147 of 155 classified programs — the dominant modality here.

5%ALL OTHERSPeptide53%Protein / enzyme32%

Small molecule leads; the ring shows all 155 classified programs, each share of the total. Modality classified for 96% of 166 pipeline programs.

Trial Status

114

clinical trials

Completed52 · 46%
Recruiting27 · 24%
Active, not recruiting9 · 8%
Unknown status8 · 7%
Terminated7 · 6%
Not yet recruiting5 · 4%
Other6 · 5%

Trial Activity

114 trials

Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease
Recruiting··Phase 2·NCT06679374·102 enrolled
Montelukast in Parkinson Disease
Recruiting··Phase 2/3·NCT06113640·60 enrolled
Fexofenadine as Adjuvant Therapy in Parkinson Disease
Recruiting·TTanta University·Phase 2/3·NCT06785298·46 enrolled
Metformin in Parkinson Disease
Recruiting·TTanta University·Phase 2/3·NCT07229651·60 enrolled
Celecoxib in Parkinson Disease as Adjuvant Therapy
Recruiting·TTanta University·Phase 1/2·NCT07246278·80 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)