VivoSeq
Other

Platelet Aggregation

32

Pipeline Programs↗

2

Active Trials↗

13

Companies Involved↗

Platelet Aggregation is a moderately active landscape with 32 programs across 13 companies. The most active players are GSK, Tanabe Pharma Corporation, Daiichi Sankyo. 14 therapies are approved with 3 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

53/100

Pipeline Velocity

0/100

Mech. Concentration

11/100

Completion Rate

80/100

Attrition Rate

15/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

GSK logo

GSK

2 programs

Phase 1Tanabe Pharma Corporation logo

Tanabe Pharma Corporation

1 program

Phase 3Daiichi Sankyo logo

Daiichi Sankyo

1 program

Phase 3Bayer logo

Bayer

2 programs

ApprovedSanofi logo

Sanofi

1 program

ApprovedA

Amring

1 program

Approved

Pipeline

Programs by Phase

Analysis

Modality Breakdown

97%

Small molecule

34 of 35 classified programs — the dominant modality here.

3%ALL OTHERSMonoclonal antibody13%

Small molecule leads; the ring shows all 35 classified programs, each share of the total. Modality classified for 100% of 35 pipeline programs.

Analysis

Trial Status

26

clinical trials

Completed16 · 62%
Unknown status4 · 15%
Recruiting2 · 8%
Withdrawn2 · 8%
Terminated2 · 8%

Clinical Trials

Trial Activity

26 trials

Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE
Recruiting·SSichuan Provincial People's Hospital·Phase 3·NCT06853535·5,138 enrolled
Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Ischemic STROKE（PATH-STROKE）
Recruiting·SSichuan Provincial People's Hospital·Phase 4·NCT06269432·1,020 enrolled
Platelet Aggregation During the Shift From Clopidogrel to Ticagrelor
Completed·UUniversity Magna Graecia·N/A·NCT01795820·50 enrolled
Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO)
Completed·Sanofi logoSanofi·Phase 2·NCT00115375·92 enrolled
Effect of Steady State Meloxicam on Low Dose Aspirin Induced Inhibition of Platelet Aggregation and Thromboxane Synthesis in Healthy Males and Females
Completed·Boehringer Ingelheim logoBoehringer Ingelheim·Phase 1·NCT02187562·16 enrolled
Impact of Dabigatran and Phenprocoumon on ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation
Completed·—·Phase 4·NCT01339819·70 enrolled
Effect of Sarpogrelate on Platelet Aggregation in Patients With Cerebral Infarction: Dose-responsive Clinical Pharmacology Study
Completed·Tanabe Pharma Corporation logoTanabe Pharma Corporation·Phase 3·NCT00147303·46 enrolled
Effect Of Rilapladib (SB-659032) On Platelet Aggregation
Completed·GSK logoGSK·Phase 1·NCT00387257·58 enrolled
Effects of Acetylsalicylic Acid Compared With the Combination of Acetylsalicylic Acid + Modified-release Dipyridamole on Serum Thromboxane B2 Formation and Platelet Aggregation in Healthy Volunteers
Completed·Boehringer Ingelheim logoBoehringer Ingelheim·Phase 1·NCT02268773·27 enrolled
The Platelet Aggregation After tiCagrelor Inhibition and FentanYl Trial (PACIFY)
Completed·JJohns Hopkins University·Phase 4·NCT02683707·212 enrolled
SB-659032 Platelet Aggregation Study
Completed·GSK logoGSK·Phase 1·NCT01745458·26 enrolled
Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation in Analgetic Dosages
Completed·RRuhr University of Bochum·N/A·NCT00763997·80 enrolled
Is Efficacy of PLAtelet Aggregation Inhibition by Ticagrelor Mediated P2Y12 Blockade Dependent Upon Endogenous Endothelial Nitric OXide?
Completed·HHull University Teaching Hospitals NHS Trust·Phase 4·NCT02169596·74 enrolled
Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidation
Completed·ZZiv Hospital·Phase 4·NCT00466401·20 enrolled
Arachidonic Acid-induced Platelet Aggregation Rate in Patients With Stable CAD Treated With Ticagrelor Monotherapy
Completed·—·Phase 4·NCT02219412·70 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)