Dipyrone

Phase 3Small molecule

EEMS

Dipyrone is one of 20 small molecule programs targeting Intrapartum Fever. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Intrapartum FeverNot yet recruiting

Platelet AggregationActive, not recruiting

Intrapartum FeverPhase 3

Not yet recruiting

Platelet AggregationPreclinical

Active, not recruiting

Competition

Competitive Landscape

22 competitors in Platelet Aggregation

#DrugCompanyPhaseTrials

Bayer Aspirin

Bayer

Approved

4 2

Brilinta

AstraZeneca

Approved

4 3

Plavix

Sanofi

Approved

3 4

Pradaxa

Boehringer Ingelheim

Approved

2 5

Xylocaine

MMEDRx USA, Inc.

Approved

1 6

Effient

CCosette Pharmaceuticals, Inc.

Approved

1 7

Zocor

OOrganon and Co

Approved

1 8

Zetia

OOrganon and Co

Approved

1 9

Pletal

Otsuka

Approved

1 10

Versed

CConrado Roberto Hoffmann Filho

Approved

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

Phase 3Not yet recruiting

Efficacy and Safety

NCT06237231

Post-ApprovalNot yet recruiting

Intrapartum Fever

NCT06950840

Clinical

Trials by Indication[1]

Efficacy and Safety2 trials

Efficacy and Safety of Tiradentes Association in the Treatment of Acute Pain

Withdrawn·EEMS·Phase 2·NCT04593329

Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars

Not yet recruiting·EEMS·Phase 3·NCT06237231·252 enrolled

Patient Preference1 trial

Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients

Withdrawn·WWestern Galilee Hospital-Nahariya·N/A·NCT01263652

Spinal Anesthesia1 trial

Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia

Completed·—·Phase 2·NCT01858402·2 enrolled

Gastroenteritis1 trial

Optimal Analgesia in Acute Gastroenteritis

Terminated·HHadassah Medical Organization·Phase 3·NCT02711241·15 enrolled

Abdominal Surgery1 trial

Fixed Combination of Dipirone and Codeine Compared to the Isolated Use of Dipyrone and Codeine in Controlling Pain After Pelvic-abdominal Surgery.

Completed·—·Phase 3·NCT04641338·491 enrolled

5 more indications

Chronic pain1 trial

Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain

Withdrawn·EEMS·Phase 2·NCT05125978

Delirium1 trial

Delirium in Elderly Patients With Trauma of the Hip

Terminated·—·Phase 4·NCT02689024·239 enrolled

Intrapartum Fever1 trial

Antipyretic Treatment for Intrapartum Fever: Dipyrone vs Acetaminophen (RCT)

Not yet recruiting·WWolfson Medical Center·Phase 4·NCT06950840·140 enrolled

Platelet Aggregation1 trial

Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation in Analgetic Dosages

Completed·RRuhr University of Bochum·N/A·NCT00763997·80 enrolled

Cesarean Section1 trial

Comparing Protocols for Analgesia Following Elective Cesarean Section

Unknown status·WWolfson Medical Center·Phase 4·NCT03622489·120 enrolled

Sources

References

[1]
ClinicalTrials.gov — 11 trial records for Dipyrone. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Dipyrone compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Dipyrone. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — EMS company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: EEMS

Dipyrone

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2027

Trials by Indication[1]

Efficacy and Safety2 trials

Patient Preference1 trial

Spinal Anesthesia1 trial

Gastroenteritis1 trial

Abdominal Surgery1 trial

Chronic pain1 trial

Delirium1 trial

Intrapartum Fever1 trial

Platelet Aggregation1 trial

Cesarean Section1 trial

References

Drug Info

Quick Facts

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