VivoSeq
Other

Skin Aging

10

Pipeline Programs↗

3

Active Trials↗

6

Companies Involved↗

Skin Aging is an early-stage landscape with 10 programs across 6 companies. The most active players are Piezo Therapeutics, Inc., Eastern Cooperative Oncology Group, Vitae Pharmaceuticals Inc., an Allergan affiliate. 3 therapies are approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

38/100

Pipeline Velocity

11/100

Mech. Concentration

33/100

Completion Rate

71/100

Attrition Rate

18/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

P

Piezo Therapeutics, Inc.

1 program

Phase 1E

Eastern Cooperative Oncology Group

1 program

Phase 1V

Vitae Pharmaceuticals Inc., an Allergan affiliate

1 program

Phase 3I

Inflabloc Pharmaceuticals

1 program

Phase 3R

Revance Therapeutics, Inc.

1 program

PreclinicalV

Valeant Pharmaceuticals

1 program

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

11

clinical trials

Completed5 · 45%
Terminated2 · 18%
Not yet recruiting2 · 18%
Unknown status1 · 9%
Active, not recruiting1 · 9%

Clinical Trials

Trial Activity

11 trials

Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure
Active, not recruiting·JJohns Hopkins University·Phase 1·NCT03730649·12 enrolled
The Efficienctiveness of Poly-L-Lactic Acid, PLLA for the Treatment of Skin Laxity of the Neck: A Pilot Study
Not yet recruiting·Institute of Dermatology, Thailand·Preclinical·NCT07689344·10 enrolled
An Open-Label, Within Participant-Controlled, First-in-Human (FIH) Study to Explore the Safety, Tolerability, and Pharmacodynamic Effects of PIEZO-101, an Investigational Plasmid DNA Biostimulator Delivered by Intradermal Electroporation to the Knee and Décolleté Regions in Healthy Adult Female Participants
Not yet recruiting·PPiezo Therapeutics, Inc.·Phase 1·NCT07671027·8 enrolled
Effects on Facial Skin Aging After Topical Application of Exosomes With a Microneedling Device
Completed·IInstituto de Oftalmología Fundación Conde de Valenciana·Phase 4·NCT07372001·30 enrolled
Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women
Completed·SStanford University·N/A·NCT00541931·37 enrolled
Effect of DHEA on Skin Aging in Postmenopausal Women
Completed·—·Phase 3·NCT00248989·150 enrolled
Efficacy of Extract of Trigonella Foenum-graceum as Topical Phytoestrogen in Skin Aging Treatment of Post Menopausal Women
Completed·IIndonesia University·Phase 1/2·NCT04123743·21 enrolled
Retinol on Human Skin Aging in East Asian Descent
Completed·SStanford University·Phase 4·NCT02906566·110 enrolled
An Evaluation of Kinerase Pro+Therapy Regimen Vs. Kinerase Vs. Control for the Treatment of Skin Aging
Terminated·IInnovative Medical·Phase 4·NCT00492479
Effect of Topical Sulforaphane on Skin Fragility Seen in Skin Aging and With Ultraviolet Exposure
Terminated·JJohns Hopkins University·Phase 2·NCT03126539·9 enrolled
Autologous Platelet-Rich Plasma Cream for Photoaging and Chronological Skin Aging
Unknown status·—·Phase 1/2·NCT02303496·20 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)