VivoSeq
Other

Syncope

8

Pipeline Programs↗

1

Active Trials↗

6

Companies Involved↗

Syncope is an early-stage landscape with 8 programs across 6 companies. The most active players are Amgen, Novartis, Takeda. 2 therapies are approved with 2 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

34/100

Pipeline Velocity

0/100

Mech. Concentration

17/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Amgen logo

Amgen

1 program

Phase 1Novartis logo

Novartis

1 program

Phase 3Takeda logo

Takeda

1 program

PreclinicalPfizer logo

Pfizer

1 program

PreclinicalAstellas logo

Astellas

1 program

PreclinicalAstraZeneca logo

AstraZeneca

1 program

Preclinical

Pipeline

Programs by Phase

Analysis

Trial Status

9

clinical trials

Completed7 · 78%
Unknown status1 · 11%
Not yet recruiting1 · 11%

Clinical Trials

Trial Activity

9 trials

Study of Ondansetron in the Prevention of Sleep Syncope: The Nineth Prevention of Syncope Trial (POST9)
Not yet recruiting·UUniversity of Calgary·Phase 3·NCT05657925·24 enrolled
Stop Vasodepressor Drugs in Reflex Syncope
Completed·GGruppo Italiano Multidisciplinare per lo Studio della Sincope·Phase 3·NCT02137278·58 enrolled
The Effectiveness of Metoprolol in the Prevention of Syncope Recurrence in Children and Adolescents
Completed·PPeking University First Hospital·N/A·NCT00475462·28 enrolled
Randomized Study of Midodrine, an Alpha Adrenergic Agonist, in Patients With Neurally Mediated Syncope
Completed·IIcahn School of Medicine at Mount Sinai·N/A·NCT00004479
Diagnostic Yield of an Ambulatory Patch Monitor in Unexplained Emergency Department Syncope: A Pilot Study (PATCH-ED)
Completed·NNHS Lothian·N/A·NCT02683174·86 enrolled
Rapid Measurement of Adenosine in Syncope Patients
Completed·—·N/A·NCT05782712·235 enrolled
Prevalence of PE in ED Patients With Isolated Syncope
Completed·AAssistance Publique - Hôpitaux de Paris·N/A·NCT03487237·459 enrolled
Theophylline for Low Adenosine Syncope
Completed·CCentro Prevenzione Malattie Cardiovascolari N. e V. Corbella·N/A·NCT03803215·77 enrolled
Correlation Between Vitamin D and Symptoms Severity of Autonomic Nervous Mediated Syncope Child and it 's RAAS
Unknown status·KKongyujie·Phase 1·NCT04844957·100 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)