VivoSeq
Musculoskeletal

Temporomandibular Joint Disorder

19

Pipeline Programs↗

0

Active Trials↗

12

Companies Involved↗

Temporomandibular Joint Disorder is an emerging landscape with 19 programs across 12 companies. The most active players are Kenvue Brands, Vitae Pharmaceuticals Inc., an Allergan affiliate, Immunex. 6 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

45/100

Pipeline Velocity

0/100

Mech. Concentration

15/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

K

Kenvue Brands

1 program

Phase 1V

Vitae Pharmaceuticals Inc., an Allergan affiliate

1 program

Phase 2I

Immunex

1 program

Phase 2Amgen logo

Amgen

1 program

Phase 2S

Specgx

1 program

Phase 2C

Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

1 program

Phase 2

Pipeline

Programs by Phase

Analysis

Modality Breakdown

90%

Small molecule

19 of 21 classified programs — the dominant modality here.

10%ALL OTHERSMonoclonal antibody15%Protein / enzyme15%

Small molecule leads; the ring shows all 21 classified programs, each share of the total. Modality classified for 100% of 23 pipeline programs.

Analysis

Trial Status

6

clinical trials

Completed6 · 100%

Clinical Trials

Trial Activity

6 trials

Effectiveness of Vitamin B in Reducing Temporomandibular Joint Disorder Pain
Completed·TThe University of Hong Kong·Phase 2·NCT02794922·27 enrolled
Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder
Completed·—·N/A·NCT06839326·75 enrolled
Low Level Laser Therapy in the Treatment of Temporomandibular Joint Disorders (TMJDs) Related Pain
Completed·UUniversity of Roma La Sapienza·N/A·NCT03119324·90 enrolled
Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD).
Completed·SSpherium Biomed·Phase 1/2·NCT02602483·96 enrolled
Comparison of Psychological and Pharmacological Treatments for Pain Due to Temporomandibular Joint Disorder (TMD)
Completed·JJohns Hopkins University·Phase 2·NCT00066937·140 enrolled
Duloxetine for Treatment of Painful Temporomandibular Joint Disorder
Completed·UUniversity of Maryland, Baltimore·N/A·NCT00981149·24 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)