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Alcohol

ApprovedSmall molecule

Alcohol is not a pharmaceutical drug in the traditional sense, but ethanol is used medically in some cases such as treatment for certain types of poisoning (like methanol or ethylene glycol poisoning) and historically as an antiseptic and disinfectant.[2] Alcohol is currently approved and in use across 46 indications[4].[1]

Alcohol is one of 879 small molecule programs targeting HIV infection. It is currently in Approved.

46

Indications

58

Total Trials

19

Active Trials

878

Competitors

Pipeline

Status by Indication[4][1]

Indication

HIV InfectionActive, not recruiting

NeutropeniaActive, not recruiting

Large Congenital Melanocytic NevusActive, not recruiting

Erectile DysfunctionActive, not recruiting

HyperhidrosisActive, not recruiting

AlopeciaActive, not recruiting

Ventricular TachycardiaActive, not recruiting

Central Nervous System NeoplasmActive, not recruiting

Cystic, Mucinous, and Serous NeoplasmActive, not recruiting

TremorActive, not recruiting

HIV InfectionPreclinical

Active, not recruiting

NeutropeniaPhase 3

Active, not recruiting

Large Congenital Melanocytic NevusPhase 1

Active, not recruiting

Erectile DysfunctionPhase 1

Active, not recruiting

HyperhidrosisPhase 1

Active, not recruiting

AlopeciaPhase 2

Active, not recruiting

Ventricular TachycardiaPhase 3

Active, not recruiting

Central Nervous System NeoplasmPhase 2

Active, not recruiting

Cystic, Mucinous, and Serous NeoplasmPhase 1

Active, not recruiting

TremorPhase 2

Active, not recruiting

Showing 10 of 43 indications

Competition

Competitive Landscape

1931 competitors in COVID-19

#DrugCompanyPhaseTrials

Alcohol

Bnt162b2

Piperacillin/tazobactam

Nadroparin

HB-Admscs

HHope Biosciences Research Foundation

Aprotinin

Biological Collection

AAssistance Publique - Hôpitaux de Paris

Antithrombin-III

Interferon-Gamma

SSPP Pharmaclon Ltd.

MRNA COVID-19 Vaccine

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Phase 2Recruiting

Alcohol Intoxication

NCT06118580

Phase 1Recruiting

Sex Differences

NCT03827460

Q4 2026

Essential Tremor

NCT06293638

Phase 1Recruiting

Alcohol Drinking

NCT03294460

Q1 2027

Phase 1Recruiting

Alcohol

NCT06326684

Phase 2Recruiting

Alcohol Consumption

NCT05389930

Clinical

Trials by Indication[1]

Alcohol14 trials

Imaging Glutamate Release From Alcohol

Completed·YYale University·Phase 1·NCT04159688·8 enrolled

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

Recruiting·UUniversity of Illinois at Urbana-Champaign··NCT05692830·240 enrolled

Suvorexant and Alcohol

Recruiting·WWilliam Stoops·Phase 1·NCT06326684·30 enrolled

Show 11 more trials

Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)

Completed·CCraig Rush·Phase 1·NCT03575403·19 enrolled

Understanding Alcohol Reward in Social Context

Completed·UUniversity of Illinois at Urbana-Champaign·N/A·NCT03449095·640 enrolled

Effects of Alcohol on Simulated Driving

Completed·UUtrecht Institute for Pharmaceutical Sciences·N/A·NCT00477984·32 enrolled

Behavioral Alcohol Responses (BAR) Study

Active, not recruiting·—·Phase 1·NCT03467191·782 enrolled

Alcohol and Implicit Process in Sexual Risk Behavior in MSM

Completed·SSyracuse University·Phase 1·NCT03361384·260 enrolled

The Behavioral Effects of Opioids and Alcohol

Completed·SSharon Walsh·Phase 1·NCT04300751·11 enrolled

Social Effects of Alcohol

Completed·UUniversity of Chicago·Phase 1·NCT05826951·37 enrolled

Impulsivity and Alcohol Response

Terminated·UUniversity of Florida·Phase 1·NCT03736343·24 enrolled

Metabolic Effects of Alcohol

Completed·—·N/A·NCT00167115·20 enrolled

Motivation for IV Alcohol Self-Administration in Humans

Recruiting·UUniversity of California, Los Angeles·Phase 2·NCT06494891·210 enrolled

Alcohol and Sexual Communication Among Couples in the Laboratory

Recruiting·UUniversity of Colorado, Denver·N/A·NCT06865872·480 enrolled

Impairment3 trials

The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment

Completed·JJohns Hopkins University·Phase 1·NCT04931095·60 enrolled

Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment

Recruiting·JJohns Hopkins University·Phase 1·NCT06293040·90 enrolled

Cannabis Impairment Detection Application (CIDA)

Completed·AAdvanced Brain Monitoring, Inc.·N/A·NCT04230460·124 enrolled

Alcohol Effect3 trials

Influence of n-Acetylcysteine Maintenance on Alcohol Effects

Completed·WWilliam Stoops·Phase 1·NCT03216954·14 enrolled

Alcohol Effects on Driving-related Skills of Young Drivers

Completed·CCentre for Addiction and Mental Health·N/A·NCT02710578·30 enrolled

Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults

Recruiting·UUniversity of Southern California·N/A·NCT06627803·200 enrolled

Cannabis2 trials

Combined Alcohol and Cannabis Effects on Skills of Young Drivers

Completed·CCentre for Addiction and Mental Health·Phase 1·NCT03106363·85 enrolled

Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests

Withdrawn·UUniversity of California, San Diego·Phase 1/2·NCT05273658

Sex Differences2 trials

Neural and Hormonal Influences on Sex Differences in Risk for AUD

Recruiting·JJessica Weafer·N/A·NCT04929288·100 enrolled

Sex Differences in the Response to Abstinence From Alcohol.

Recruiting·IIndiana University·Phase 1·NCT03827460·160 enrolled

32 more indications

Interaction2 trials

Mephedrone and Alcohol Interactions in Humans

Completed·PParc de Salut Mar·Phase 1·NCT02294266·12 enrolled

Study of Lemborexant-Alcohol Interaction in Healthy Subjects

Completed· Eisai logo

Eisai·Phase 1·NCT03483636·24 enrolled

Marijuana1 trial

Marijuana Effects on Simulated Driving Performance

Completed·SShanna Babalonis, PhD·Phase 1·NCT03699540·10 enrolled

Adult Subject1 trial

A Study to Assess Potential Interaction Between ASP8062 and Alcohol in Healthy Adult Subjects

Completed· Astellas logo

Astellas·Phase 1·NCT04003402·20 enrolled

Trial1 trial

The TARGET BP OFF-MED Trial

Completed·AAblative Solutions, Inc.·Phase 2·NCT03503773·350 enrolled

Hyperhidrosis1 trial

Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2

Completed·UUniversity of Utah·Phase 1·NCT03416348·95 enrolled

Oral1 trial

Behavioral Economics of Human Drug Self-Administration

Completed·NNational Center for Research Resources (NCRR)··NCT00005765

Alcohol Use Disorder1 trial

PT150 Drug for Use in Alcohol Use Disorder

Recruiting·PPop Test Oncology LLC·Phase 1·NCT06712602·34 enrolled

TED1 trial

Computer-Assisted Self-Administration of Ethanol

Completed·NNational Institute on Alcohol Abuse and Alcoholism (NIAAA)·Phase 1·NCT00713492·229 enrolled

Impaired Driving1 trial

Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving

Completed·RRush University Medical Center·Phase 3·NCT00559819·32 enrolled

Effectiveness1 trial

Effectiveness of Alcohol Swabs for Preventing Infections During Vaccination

Unknown status·UUniversity of Toronto·Phase 3·NCT03131843·170 enrolled

Alcohol Consumption1 trial

Cannabis' Impact on Alcohol Consumption

Recruiting·—·Phase 2·NCT05389930·350 enrolled

Alcohol Abuse1 trial

Sex Differences in Risk for Alcohol Abuse

Completed·MMark Fillmore·N/A·NCT04543942·28 enrolled

Heavy Drinker1 trial

Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers

Completed·NNational Institute on Alcohol Abuse and Alcoholism (NIAAA)·Phase 2·NCT01779024·17 enrolled

Treatment1 trial

Comparative Study of Polidocanol and Absolute Alcohol for Percutaneous us Guided Treatment of Benign Thyroid Cyst

Unknown status·—·Phase 4·NCT05798936·30 enrolled

Prevention1 trial

EGCG for the Prevention and Treatment of TIPN

Recruiting·HHan Xi Zhao·Phase 1/2·NCT06524609·36 enrolled

AIN1 trial

Impulsivity Domains and Subjective Response

Recruiting·JJessica Weafer·Phase 1·NCT05929677·250 enrolled

Smokers1 trial

Effects of Varenicline in Heavy Drinking Smokers

Withdrawn·UUniversity of California, Los Angeles·Phase 4·NCT02488889

Alcohol Use Disorders1 trial

Development of Ivermectin for Alcohol Use Disorders

Completed·UUniversity of California, Los Angeles·Phase 1/2·NCT02046200·11 enrolled

Alcohol Intoxication1 trial

Neural Correlates During Alcohol Intoxication

Recruiting·OOhio State University·Phase 2·NCT06118580·144 enrolled

Hepatitis C1 trial

Interaction of Alcohol and Highly Active Antiretroviral Therapy (HAART) in HIV/AIDS and HIV/AIDS With Hepatitis C Virus (HCV) Co-Infection

Completed·UUniversity of California, San Francisco·Phase 1·NCT00879047·30 enrolled

Function1 trial

Effects of Acetate and Alcohol on Brain Function

Completed·UUniversity of Colorado, Denver·N/A·NCT02542150·24 enrolled

Tremor1 trial

Effect of Alcohol on Tremors

Completed·NNational Institute of Neurological Disorders and Stroke (NINDS)·Phase 2·NCT00001925·23 enrolled

Essential Tremor1 trial

Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor

Recruiting·TThe Cleveland Clinic··NCT06293638·55 enrolled

Type 2 Diabetes1 trial

Moderate Alcohol Intake Among Patients With Type 2 Diabetes

Completed·IIris Shai·Phase 2·NCT00295334·109 enrolled

Oral Cancer1 trial

Role of Acetaldehyde in the Development of Oral Cancer

Recruiting·MMasonic Cancer Center, University of Minnesota·N/A·NCT05973656·170 enrolled

Anesthesia1 trial

Ethyl Chloride Vapocoolant as Anesthesia for Arterial Punctures

Completed·BBionorte·N/A·NCT02587143·126 enrolled

Steroid1 trial

An Investigator-Initiated Study to Assess the Cooling Effect of Triamcinolone Acetonide Aerosol When Used for Steroid-Responsive Dermatoses

Completed·PPatel, Rita Vikram, M.D.·N/A·NCT01736670·30 enrolled

Cancer Pain1 trial

Endoscopic Ultrasound Guided Coeliac Plexus Neurolysis for Cancer Pain

Unknown status·TThe University of Hong Kong·Phase 4·NCT04801082·54 enrolled

Bariatric Surgery1 trial

Alcohol After Bariatric Surgery 2

Recruiting·UUniversity of Illinois at Urbana-Champaign··NCT06257771·88 enrolled

Menstrual Cycle1 trial

Estradiol Effects on Alcohol Across the Menstrual Cycle

Completed·MMark Fillmore·N/A·NCT04595682·100 enrolled

Alcohol Drinking1 trial

Nicotinic Receptor Genetic Variation and Alcohol Reward

Recruiting·NNational Institute on Alcohol Abuse and Alcoholism (NIAAA)·Phase 1·NCT03294460·128 enrolled

Unspecified2 trials

Residual Effects of Intoxication on Student Performance

Completed·—·Phase 2·NCT00183170·239 enrolled

Ethanol Consumption in the Heat

Recruiting·LLakehead University·N/A·NCT06935045·34 enrolled

Sources

References

[1]
ClinicalTrials.gov — 58 trial records for Alcohol. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Alcohol drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — Alcohol compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for Alcohol. EMBL-EBI & Wellcome Sanger Institute.
[5]
SEC EDGAR — Astellas company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: Astellas

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