VivoSeq
Cardiovascular

Thromboembolism

28

Pipeline Programs↗

2

Active Trials↗

11

Companies Involved↗

Thromboembolism is an emerging landscape with 28 programs across 11 companies. The most active players are Bayer, Sanofi, Italfarmaco. 10 therapies are approved with 8 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

51/100

Pipeline Velocity

6/100

Mech. Concentration

33/100

Completion Rate

100/100

Attrition Rate

0/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Bayer logo

Bayer

3 programs

Phase 2Sanofi logo

Sanofi

3 programs

Phase 3Italfarmaco logo

Italfarmaco

1 program

Phase 3G

Gynecologic Oncology Group

1 program

Phase 3Daiichi Sankyo logo

Daiichi Sankyo

1 program

Phase 3Pfizer logo

Pfizer

2 programs

Phase 3

Pipeline

Programs by Phase

Analysis

Modality Breakdown

97%

Small molecule

31 of 32 classified programs — the dominant modality here.

3%ALL OTHERSProtein / enzyme13%

Small molecule leads; the ring shows all 32 classified programs, each share of the total. Modality classified for 100% of 32 pipeline programs.

Analysis

Trial Status

24

clinical trials

Completed19 · 79%
Unknown status3 · 13%
Not yet recruiting1 · 4%
Recruiting1 · 4%

Clinical Trials

Trial Activity

24 trials

Long-Term CLinical Evaluation of Aspiration ThRombectomy Using the Symphony or ProdIgy Thrombectomy System - CLEAR-IT
Recruiting·IImperative Care, Inc.·N/A·NCT07350499·750 enrolled
The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity
Not yet recruiting·UUniversity of Calgary·Phase 3·NCT06494878·8,805 enrolled
Prevention of Venous and Arterial Thromboembolism, in Cancer Patients Undergoing Chemotherapy, With a Low Molecular Weight Heparin (Nadroparin Calcium)
Completed·Italfarmaco logoItalfarmaco·Phase 3·NCT00951574·1,166 enrolled
The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients
Completed·—·Phase 2/3·NCT00531843·105 enrolled
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Total Hip Replacement Surgery
Completed·Sanofi logoSanofi·Phase 3·NCT00697099·2,326 enrolled
Nadroparin for the Initial Treatment of Pulmonary Thromboembolism
Completed·—·Phase 4·NCT00796692·274 enrolled
ThromboEmbolism Prevention Efficacy and Safety Trial (TEMPEST)
Completed·GSK logoGSK·Phase 2·NCT00041509·343 enrolled
PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT Pilot)
Completed·HHamilton Health Sciences Corporation·Phase 3·NCT00182364·120 enrolled
The Treatment of Acute Pulmonary Thromboembolism (PE) of GSK576428 (Fondaparinux Sodium) in Japanese Patients
Completed·GSK logoGSK·Phase 3·NCT00981409·41 enrolled
Pilot PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity
Completed·UUniversity of Calgary·Phase 1·NCT04153760·257 enrolled
Low Dosage of rt-PA in the Treatment of Pulmonary Thromboembolism in China
Completed·—·Phase 4·NCT00781378·118 enrolled
12-h and 2-h Urokinase Regimes of Pulmonary Thromboembolism in China
Completed·—·Phase 4·NCT00799968·129 enrolled
Risk Stratification Procedure for Thromboembolism Prophylaxis
Completed·Ministry of Health, Saudi Arabia·Phase 2·NCT04031859·242 enrolled
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Elective Knee Replacement Surgery
Completed·Sanofi logoSanofi·Phase 3·NCT00718224·1,150 enrolled
Selective Thromboembolism Prophylaxis After Arthroplasty
Completed·GGuangdong Provincial People's Hospital·N/A·NCT03804697·197 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)