Prilosec

(Omeprazole)

ApprovedSmall molecule

Omeprazole reduces stomach acid to treat heartburn, acid reflux, and ulcers. It helps relieve the pain and discomfort caused by excess stomach acid.[2] Prilosec is currently approved and in use across 69 indications[4].[1]

Prilosec is one of 1136 small molecule programs targeting Dyspepsia. It is currently in Approved.

Indications

276

Total Trials

Active Trials

1,135

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

DyspepsiaUnknown status

Eosinophilic EsophagitisApproved

Squamous Cell Intraepithelial NeoplasiaApproved

Depressive DisorderActive, not recruiting

OsteoarthritisActive, not recruiting

Ankylosing SpondylitisActive, not recruiting

SpondylitisActive, not recruiting

Clostridium Difficile InfectionApproved

Spinal Muscular AtrophyApproved

Type 1 Diabetes MellitusApproved

DyspepsiaApproved

Unknown status

Eosinophilic EsophagitisApproved

Approved

Squamous Cell Intraepithelial NeoplasiaApproved

Approved

Depressive DisorderPreclinical

Active, not recruiting

OsteoarthritisApproved

Active, not recruiting

Ankylosing SpondylitisApproved

Active, not recruiting

SpondylitisApproved

Active, not recruiting

Clostridium Difficile InfectionApproved

Approved

Spinal Muscular AtrophyApproved

Approved

Type 1 Diabetes MellitusApproved

Approved

Showing 10 of 67 indications

Competition

Competitive Landscape

744 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Prilosec

DDexcel Pharma Technologies Ltd.

Approved

4 2

Lexiscan

Astellas

Preclinical

1 3

Voltaren

Novartis

Preclinical

1 4

Zolymbus

AbbVie

Preclinical

1 5

Blenoxane

Bristol-Myers Squibb

Preclinical

1 6

Methylthioninium Chloride

PProvepharm SAS

Preclinical

3 7

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

3 8

Duragesic-100

CCephalon

Preclinical

2 9

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

2 10

Spravato

WWim Janssens

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 3Not yet recruiting

Efficacy

NCT04069286

Q3 2027

Phase 1Recruiting

Pancreatic Cancer

NCT04930991

Q4 2027

Phase 2Recruiting

Breast Cancer

NCT06150898

Q1 2028

Post-ApprovalNot yet recruiting

Breast Disease

NCT06943482

Phase 2Recruiting

Prostate Cancer

NCT04337580

Clinical

Trials by Indication[1]

Interaction15 trials

Interaction Study of Clopidogrel 600/150 mg Given Alone or Concomitantly With Omeprazole 80 mg in Healthy Subjects

Completed· Sanofi logo

Sanofi·Phase 1·NCT01129414·72 enrolled

Interaction Study of Clopidogrel 300/75 mg Given Alone or With Omeprazole 80 mg 12 Hours Apart in Healthy Subjects

Completed· Sanofi logo

Sanofi·Phase 1·NCT01129388·72 enrolled

A Drug Interaction Study of the Effects of PPI-668 on the Pharmacokinetics of Midazolam and Omeprazole

Completed·PPresidio Pharmaceuticals, Inc.·Phase 1·NCT01786382·24 enrolled

Show 12 more trials

Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers

Completed·UUniversity of Sarajevo·Phase 1·NCT04198948·15 enrolled

GSK1349572 Proton Pump Inhibitor Drug Interaction and Supratherapeutic Dose Study

Completed· GSK logo

GSK·Phase 1·NCT00942136·24 enrolled

A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT05852769·18 enrolled

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Withdrawn· Takeda logo

Takeda·Phase 4·NCT02760615

A Study to Evaluate the One-way Interaction of Calcium Carbonate, Omeprazole, or Rifampin on ACP-196

Completed·AAcerta Pharma BV·Phase 1·NCT04914936·72 enrolled

Drug-drug Interaction Study of KL1333 in Healthy Subjects

Completed·AAbliva AB·Phase 1·NCT04643249·14 enrolled

Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

Completed· Daiichi Sankyo logo

Daiichi Sankyo·Phase 1·NCT01517399·28 enrolled

Study to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants

Completed· Amgen logo

Amgen·Phase 1·NCT05581992·14 enrolled

Pharmacokinetic Drug-Drug Interaction Study of Rucaparib

Completed·Ppharmaand GmbH·Phase 1·NCT02740712·17 enrolled

Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults

Completed· GSK logo

GSK·Phase 1·NCT04425902·20 enrolled

Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)

Completed·GGrünenthal GmbH·Phase 1·NCT03979989·32 enrolled

Study Evaluating the Drug Interaction Potential of Luliconazole Cream 1% in Participants With Tinea Pedis and Tinea Cruris

Completed·BBausch & Lomb Incorporated·Phase 4·NCT02394340·20 enrolled

Tics14 trials

Evaluation of the Effects of Omeprazole and Rifampin on the Pharmacokinetics of VX-548 in Healthy Participants

Completed· Vertex Pharmaceuticals logo

Vertex Pharmaceuticals·Phase 1·NCT05635110·31 enrolled

Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 4·NCT01766050·45 enrolled

To Evaluate the Effect of Ritonavir or Omeprazole on the Pharmacokinetics of Samatasvir (IDX719) in Healthy Participants (MK-1894-006)

Completed· Merck & Co. logo

Merck & Co.·Phase 1·NCT01813552·24 enrolled

Show 11 more trials

A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With Omeprazole

Completed·AAcerta Pharma BV·Phase 1·NCT04876807·36 enrolled

A Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of BMS-986205 in Healthy Participants

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT03936374·16 enrolled

A Study to Investigate the Relative Bioavailability of 2 Different Formulations of AZD4144, the Effect of Food and Omeprazole on the Pharmacokinetics of AZD4144 in Healthy Participants

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT06948006·32 enrolled

A Multiple-Dose Pharmacokinetics Study of Two Gefapixant (AF-219/MK-7264) Formulations

Completed· Merck & Co. logo

Merck & Co.·Phase 1·NCT02492776·14 enrolled

A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

Terminated· AstraZeneca logo

AstraZeneca·Phase 1·NCT04959266·5 enrolled

Study to Assess the Pharmacodynamics/Pharmacokinetics After Repeated Dosing of D961H 10 mg and Omeprazole 10 mg in Japanese Healthy Male Subjects

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT01159145·42 enrolled

Compare the Pharmacokinetics of Omeprazole, Rosiglitazone, and Desipramine When Administered With Avanafil in Healthy Male Subjects

Completed·VVIVUS LLC·Phase 1·NCT01415128·60 enrolled

Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of Vandetanib

Completed· Sanofi logo

Sanofi·Phase 1·NCT01539655·34 enrolled

A Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acidic Beverage in Healthy Volunteers

Completed· Amgen logo

Amgen·Phase 1·NCT05497557·16 enrolled

Study to Assess the Relative Bioavailability of Fixed-Dose Combination (FDC) Tablet (Simeprevir, Odalasvir and AL-335) Compared With Single Agents Administered Together, and to Assess the Effect of Multiple-Dose Lansoprazole or Omeprazole on Single-Dose Pharmacokinetics of SMV, ODV, and AL-335 (FDC)

Terminated· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT03059303·72 enrolled

Luminal Fructose Kinetics (MARTINI Study)

Recruiting·—·Phase 2·NCT06539494·22 enrolled

Peptic ulcer5 trials

Ilaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients

Completed·LLivzon Pharmaceutical Group Inc.·Phase 3·NCT03362281·540 enrolled

DLBS2411 Treatment for Ulcer Healing in Non-Bleeding Peptic Ulcers

Terminated·DDexa Medica Group·Phase 3·NCT02262169·32 enrolled

Optimal Dose of Omeprazole After Endoscopic Treatment of Bleeding Peptic Ulcers

Completed·SSingapore General Hospital·Phase 3·NCT00519519·126 enrolled

Show 2 more trials

Oral Omeprazole in Bleeding Peptic Ulcer

Unknown status·—·Phase 1·NCT04170270·100 enrolled

A Study Comparing High Dose Omeprazole Infusion Against Scheduled Second Endoscopy for Bleeding Peptic Ulcer

Completed·—·Phase 3·NCT00164931·240 enrolled

Dyspepsia4 trials

Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia

Completed·RRenJi Hospital·Phase 4·NCT01851863·262 enrolled

Use of Maytenus Ilicifolia in the Treatment of Dyspepsia

Terminated·CCasa Espirita Terra de Ismael·Phase 2·NCT01408849·4 enrolled

Endoscopic Tri-Modal Imaging to Distinguish Functional Dyspepsia From Reflux Disease

Completed·—·N/A·NCT02685150·157 enrolled

Show 1 more trial

Assessment and Management of Chronic Dyspepsia in Eastern Uganda

Completed·WWashington University School of Medicine·Phase 1·NCT04525664·376 enrolled

Drug Interactions4 trials

A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects

Completed·AAllist Pharmaceuticals, Inc.·Phase 1·NCT06162169·66 enrolled

Pharmacokinetics Study to Evaluate Drug-Drug Interactions and Safety of Elpida® in Co-Administration With Other Drugs

Completed·VViriom·Phase 1·NCT03709355·56 enrolled

A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT05109390·72 enrolled

Show 1 more trial

Drug Interactions Trial of Methoxyethyl Etomidate Hydrochloride

Completed·AAhon Pharmaceutical Co., Ltd.·Phase 1·NCT06822166·68 enrolled

104 more indications

Clopidogrel4 trials

Ranitidin Versus Omeprazole in Patients Taking Clopidogrel

Completed·UUniversity of Sao Paulo General Hospital·Phase 4·NCT01896557·92 enrolled

Impact of Omeprazole and Fluvoxamine on Platelet Response to Clopidogrel

Completed·HHadassah Medical Organization·Phase 1·NCT01269333·15 enrolled

Clopidogrel Proton-Pump Inhibitors Study

Withdrawn·SSheba Medical Center·Phase 4·NCT01016717

Show 1 more trial

Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine

Completed·TTel-Aviv Sourasky Medical Center·Phase 4·NCT00950339·63 enrolled

Adult4 trials

Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of SPD422 (Anagrelide Hydrochloride) in Healthy Adult Participants

Completed· Takeda logo

Takeda·Phase 1·NCT03866434·20 enrolled

Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants

Recruiting· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT07223671·32 enrolled

A Study of ALXN1840 (Coated and Non-coated) Administered With And Without Omeprazole In Healthy Adults

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT05319912·18 enrolled

Show 1 more trial

A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT05319899·18 enrolled

Upper Gastrointestinal Bleeding3 trials

Effects of Different Omeprazole Dosing on Gastric pH in Non-variceal Upper Gastrointestinal Bleeding

Completed·MMedical University of Bialystok·Phase 4·NCT03980496·50 enrolled

Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy

Completed·—·Phase 4·NCT00164866·638 enrolled

Comparison of Oral Rabeprazole vs. iv Omeprazole in Mild to Moderate Nonvariceal Upper Gastrointestinal Bleeding

Unknown status·KKaohsiung Medical University Chung-Ho Memorial Hospital·Phase 4·NCT00861640·200 enrolled

Adult Subject3 trials

A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT03363815·56 enrolled

A Study to Evaluate the Effect of Food, Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT02957474·18 enrolled

A Study to Investigate the Effect of GSK1605786 on Hepatic Cytochrome P450, and BCRP and OATP1B1 Transport in Healthy Adult Subjects

Completed· GSK logo

GSK·Phase 1·NCT01489943·24 enrolled

Fasting Conditions3 trials

Omeprazole Delayed Release (DR) Capsules Bioequivalence Study of Dr. Reddys Under Fasting Conditions

Completed·—·Phase 1·NCT01170169·44 enrolled

Bioequivalence Study of Omeprazole Magnesium 20 mg DR Capsules Under Fasting Conditions

Completed·—·Phase 1·NCT01045642·38 enrolled

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Completed·XXspray Pharma AB·Phase 1·NCT05433896·17 enrolled

Midazolam3 trials

Effect of BI 1181181 on Midazolam, Warfarin, Omeprazole and Digoxin

Withdrawn· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT02345304

Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT05438303·59 enrolled

A Study in Healthy Men to Test Whether Zongertinib Affects How 3 Other Medicines (Midazolam, Omeprazole, and Repaglinide) Are Taken up and Processed by the Body

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT06494761·16 enrolled

Helicobacter Pylori Infection3 trials

The Effects of a Synbiotic Addition on Eradication Therapy of Helicobacter Pylori Infection in Children

Completed·—·N/A·NCT03165253·69 enrolled

Lactobacillus Reuteri in Management of Helicobacter Pylori Infection in Dyspeptic Patients

Completed·ZZagazig University·N/A·NCT01593592·70 enrolled

Safety and Efficacy of Triple and Quadruple Regimens as First Line Therapy for Management of Helicobacter Pylori Infection in Egyptians

Completed·HHelwan University·Phase 4·NCT06315478·60 enrolled

Lymphoma3 trials

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Completed·EEpizyme, Inc.·Phase 1·NCT03028103·32 enrolled

Chlorambucil Compared With No Further Therapy Following Anti-Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach

Unknown status·LLymphoma Trials Office·Phase 3·NCT00003617·200 enrolled

Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma

Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 2·NCT00003151·96 enrolled

Atopic Dermatitis3 trials

Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4

Completed· LEO Pharma logo

LEO Pharma·Phase 1·NCT03556592·40 enrolled

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Completed· Amgen logo

Amgen·Phase 1·NCT05891119·21 enrolled

Open Label, Drug-Drug Interaction (DDI) Study of Dupilumab (REGN668/SAR231893) in Patients With Moderate to Severe Atopic Dermatitis (AD)

Completed· Regeneron logo

Regeneron·Phase 1·NCT02647086·14 enrolled

Esophagitis3 trials

Reflux Esophagitis Phase III Study (Initial Treatment)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00633932·602 enrolled

Reflux Esophagitis Phase III Study (Maintenance Treatment)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00634114·540 enrolled

A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis Patients

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 3·NCT01499368·495 enrolled

Gastroesophageal Reflux Disease3 trials

Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severity

Unknown status·BBelarusian Medical Academy of Post-Graduate Education·Phase 4·NCT02140073·60 enrolled

Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features

Terminated·—·Phase 4·NCT04028466·82 enrolled

Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis

Completed·KKhon Kaen University·Phase 1·NCT03561233·250 enrolled

Acute Coronary Syndrome2 trials

Preventing Cardiac Complication of COVID-19 Disease With Early Acute Coronary Syndrome Therapy: A Randomised Controlled Trial.

Terminated·IImperial College London·N/A·NCT04333407·320 enrolled

"Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER-

Unknown status·UUniversity of Roma La Sapienza·Phase 4·NCT02028234·150 enrolled

Metformin2 trials

Impact of OCT1 on Metformin Tolerance

Completed·NNHS Tayside·Phase 4·NCT02586636·61 enrolled

Effect of Omeprazole on Metformin

Completed·XXijing Hospital·Phase 1·NCT01711320·20 enrolled

Aspirin2 trials

To Compare the Gastroprotective Effects and Pharmacokinetic Profile of PA Versus Enteric-Coated Aspirin

Completed·PPOZEN·Phase 1·NCT00442052·80 enrolled

A Parallel Group Study to Compare the Gastroprotective Effects of PA 325 Versus 81 mg Enteric Coated Aspirin

Completed·PPOZEN·Phase 1·NCT00441519·80 enrolled

H Pylori Infection2 trials

High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population

Completed·IIcahn School of Medicine at Mount Sinai·Phase 4·NCT05342532·112 enrolled

Comparison of Omeprazole vs Vonoprazon in Treatment of H Pylori Infection

Not yet recruiting·RRehman Medical Institute - RMI·Phase 4·NCT07040839·128 enrolled

TED2 trials

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Completed·TTrio Medicines Ltd.·Phase 1·NCT01599858·49 enrolled

Risk of CYP2C19 Phenoconversion in Healthy Volunteers With Rapid, Normal, and Intermediate Predicted Metabolizers' Status

Unknown status·UUniversity Hospital, Geneva·Phase 1·NCT05264142·45 enrolled

Absorption2 trials

Does Omeprazole Decrease Intestinal Calcium Absorption?

Completed·UUniversity of Wisconsin, Madison·Phase 4·NCT00582972·23 enrolled

A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects

Completed·LLexicon Pharmaceuticals·Phase 1·NCT03302845·32 enrolled

Intravenous2 trials

Different Dose of Intravenous Omeprazole to Treat Bleeding Ulcer With Adherent Clot

Completed·FFar Eastern Memorial Hospital·Phase 4·NCT02536989·40 enrolled

Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer

Withdrawn·KKeio University·Phase 4·NCT00247130

Efficacy and Safety2 trials

Efficacy and Safety of DLBS2411 in the Management of GERD

Terminated·DDexa Medica Group·Phase 3·NCT03367195·32 enrolled

Efficacy and Safety Evaluation of Neobianacid® in GERD and EPS

Completed·AAboca Spa Societa' Agricola·Phase 4·NCT03238534·275 enrolled

Barrett's esophagus2 trials

Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation?

Completed·MMayo Clinic·Phase 4·NCT01093755·30 enrolled

Argon Plasma Coagulation for Barrett's Esophagus

Completed·MMaria Sklodowska-Curie National Research Institute of Oncology·N/A·NCT04154748·71 enrolled

MPA2 trials

iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions

Completed·UUniversity of Zurich·Phase 4·NCT02552537·44 enrolled

The Impact of Proton Pump Inhibitors on the Fecal Microbiome

Completed·MMayo Clinic·Phase 1·NCT01822977·15 enrolled

Patients With Advanced Solid Tumors2 trials

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced Solid Tumors

Completed·NNational Cancer Institute (NCI)·Phase 1·NCT01218620·17 enrolled

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Completed· Novartis logo

Novartis·Phase 1·NCT01596647·39 enrolled

Fed2 trials

Omeprazole Delayed Release (DR) Capsules Bioequivalence Study of Dr. Reddys Under Fed Condition

Completed·—·Phase 1·NCT01170182·54 enrolled

Bioequivalence Study of Omeprazole Magnesium 20 mg DR Capsule Under Fed Conditions

Completed·—·Phase 1·NCT01045434·62 enrolled

Breast Cancer2 trials

Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)

Completed·PProvidence Health & Services·Phase 1·NCT02950259·16 enrolled

Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)

Recruiting·JJules Bordet Institute·Phase 2·NCT06150898·112 enrolled

Gastric Acid2 trials

CYP2C19 Genotype Predictor of Gastric Acid Suppression

Withdrawn·MMayo Clinic·Phase 1·NCT01824199

The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid

Completed·NNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·Phase 2·NCT00001191

Rheumatoid Arthritis2 trials

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Completed·UUnknown Sponsor·Phase 1·NCT04246762·17 enrolled

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT01636557·12 enrolled

Treatment2 trials

A Study to Investigate the Pharmacodynamic Effect After Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00259051·40 enrolled

Efficacy of Low Dose of Proton Pump Inhibitor in Treatment Bleeding Ulcers

Completed·—··NCT03163680·295 enrolled

Efficacy2 trials

Evaluation of GERDOFF Efficacy in Combination With Proton Pump Inhibitor

Completed·SSOFAR S.p.A.·N/A·NCT03793556·72 enrolled

EFFICACY OF ORAL AROEIRA (Schinus Terebinthifolia Raddi) COMPARED TO OMEPRAZOLE IN DYSPEPPSIA

Not yet recruiting·IInfan Industria Quimica Farmaceutica Nacional·Phase 3·NCT04069286·474 enrolled

Gastritis2 trials

A RCT of Triple Therapy With Proton Pump Inhibitor vs Vonoprazan for Helicobacter Pylori Gastritis

Unknown status·—·Phase 4·NCT03908619·252 enrolled

Efficacy and Safety of Houtou Jianweiling Tablet in the Treatment of Chronic Non-Atrophic Gastritis

Completed·UUniversity of Karachi·Phase 2·NCT04672018·240 enrolled

Duodenal Ulcer2 trials

Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients (Phase 2)

Completed·LLivzon Pharmaceutical Group Inc.·Phase 2·NCT00953381·235 enrolled

Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients (Phase 3)

Completed·LLivzon Pharmaceutical Group Inc.·Phase 3·NCT00952978·496 enrolled

Drug Metabolism2 trials

KF2022#4-trial: Effects of a Beta Blocker and NSAID on CYP Mediated Drug Metabolism

Completed·HHelsinki University Central Hospital·N/A·NCT06566794·12 enrolled

Drug Metabolism and Antidepressant

Unknown status·UUniversity Hospital, Geneva·N/A·NCT02438072·100 enrolled

Oral2 trials

A Study of Effect of Multiple Doses of LOXO-305 on the Pharmacokinetics of Single Oral Doses of CYP1A2, CYP2C9, CYP2C19 Substrates in Healthy Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT06215430·16 enrolled

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT03058419·16 enrolled

Antibiotic-resistant Bacteria1 trial

Eradication of Antibiotic-resistant Bacteria Through Antibiotics and Fecal Bacteriotherapy

Unknown status·SStephen Harbarth·Phase 2·NCT02472600·39 enrolled

Tonsillectomy1 trial

Anti-reflux Control to Decrease Post Tonsillectomy Pain

Terminated·AAscension Health·Phase 4·NCT01777854·6 enrolled

Pancreatic Cancer1 trial

High Dose Omeprazole in Patients With Pancreatic Cancer

Recruiting·UUniversity of Oklahoma·Phase 1·NCT04930991·60 enrolled

Single Ascending Dose1 trial

A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized Males

Completed· Astellas logo

Astellas·Phase 1·NCT02220777·72 enrolled

Critically Ill Patients1 trial

Single Dose Omeprazole Versus High Dose in High-risk Critically Ill Patients.

Completed·MMenoufia University·N/A·NCT03388463·110 enrolled

Pilot Study1 trial

Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study

Completed·—·Phase 3·NCT01566474·80 enrolled

Reflux1 trial

Bronchial Hyper-responsiveness in Reflux Cough

Terminated·HHull University Teaching Hospitals NHS Trust·Phase 3·NCT00668317·5 enrolled

MALT lymphoma1 trial

Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT00002682·5 enrolled

Metastatic Head and Neck Cancer1 trial

A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer

Withdrawn·UUniversity of Michigan Rogel Cancer Center·Phase 2·NCT02013453

Back pain1 trial

Placebo In Chronic Back Pain (Phase 2)

Completed·AApkar Apkarian·Phase 4·NCT02986334·94 enrolled

Vulvar Intraepithelial Neoplasia1 trial

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3

Terminated·UUniversity of Southern California·Phase 2·NCT03267680·10 enrolled

ART1 trial

Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

Completed· Roche logo

Roche·Phase 1·NCT04718181·131 enrolled

Ascorbic Acid1 trial

Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets

Completed·IIndiana University·Phase 1·NCT04199624·11 enrolled

Idiopathic Pulmonary Fibrosis1 trial

Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF)

Completed·NNewcastle-upon-Tyne Hospitals NHS Trust·Phase 2·NCT02085018·45 enrolled

Prevention1 trial

Ulcer Prevention Study in Post Gastric Bypass Patients

Completed·UUniversity of Missouri-Columbia·Phase 4·NCT00557349·40 enrolled

AML1 trial

An Open-label, DDI Study to Investigate the Effects of Amlitelimab on the PK of Selected Cytochrome P450 Substrates

Active, not recruiting· Sanofi logo

Sanofi·Phase 1·NCT06686628·23 enrolled

PK/PD1 trial

Influence of CYP2C19 Polymorphism on PK/PD of Omeprazole

Completed·SSeoul National University Hospital·Phase 1·NCT02299687·24 enrolled

EoE1 trial

EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone

Unknown status·CClaire Daniels·Phase 4·NCT03781596·100 enrolled

HCV1 trial

Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO)

Completed·RRadboud University Medical Center·Phase 1·NCT01470690·24 enrolled

Helicobacter Pylori1 trial

Study of Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori

Unknown status·SSherief Abd-Elsalam·Phase 3·NCT02422706·120 enrolled

Advanced Solid Tumors1 trial

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Completed· Pfizer logo

Pfizer·Phase 1·NCT03864042·56 enrolled

Elderly Participants1 trial

A Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Xanomeline With Trospium Chloride Versus KarXT in Healthy Adult and Elderly Participants of Japanese Ethnicity and to Assess the Effect of Omeprazole on the PK of Xanomeline With Trospium Chloride in Healthy Adult Participants

Completed·KKaruna Therapeutics·Phase 1·NCT06605950·78 enrolled

Resistance1 trial

Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome

Withdrawn·WWest Side ENT·Phase 1·NCT00364481

Psoriasis1 trial

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT02397382·16 enrolled

Laryngomalacia1 trial

Laryngomalacia Study

Withdrawn·—·Phase 1·NCT01782560

Gut Microbiome1 trial

Factors Influencing the Human Gut Microbiome Profile in Multi-ethnic Groups of the Singapore Community (FAMES)

Completed·—·N/A·NCT02893709·36 enrolled

Clinical Trial1 trial

Comparing Omeprazole With Fluoxetine for Treatment of Non Erosive Reflux Disease and Its Subgroups: a Double-blind Placebo-controlled Clinical Trial

Completed·TTehran University of Medical Sciences·Phase 2/3·NCT01269788·144 enrolled

Safety and Efficacy1 trial

Safety and Efficacy Study of Viokase® 16 for the Correction of Steatorrhea

Completed·FForest Laboratories·Phase 3·NCT00559364·50 enrolled

Neoadjuvant Chemotherapy1 trial

Inhibiting Fatty Acid Synthase to Improve Efficacy of Neoadjuvant Chemotherapy

Completed·KKathy Miller·Phase 2·NCT02595372·42 enrolled

Psoriatic Arthritis1 trial

This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis

Completed· AbbVie logo

AbbVie·Phase 1·NCT02772601·21 enrolled

Immunodeficiency1 trial

A Study to Evaluate the Effect of Famotidine and Omeprazole on MK0518 (Raltegravir) Pharmacokinetics in Human Immunodeficiency Virus (HIV)-Infected Patients (0518-054)

Completed· Merck & Co. logo

Merck & Co.·Phase 1·NCT01000818·18 enrolled

Semaglutide1 trial

Investigating the Influence of Omeprazole on the Pharmacokinetics of Oral Semaglutide in Healthy Subjects

Completed· Novo Nordisk logo

Novo Nordisk·Phase 1·NCT02249871·54 enrolled

Cirrhosis1 trial

Proton Pump Inhibitors and Dysbiosis in Cirrhosis

Completed·HHunter Holmes Mcguire Veteran Affairs Medical Center·N/A·NCT01458990·60 enrolled

Baricitinib1 trial

A Study of Baricitinib and Omeprazole in Healthy Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT01925144·30 enrolled

Locally Advanced or Metastatic Solid Tumors1 trial

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Completed· Roche logo

Roche·Phase 1·NCT05487235·57 enrolled

Biomarkers1 trial

A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy

Completed·UUniversity of Michigan Rogel Cancer Center·Phase 1·NCT06378398·21 enrolled

Multiple Sclerosis1 trial

An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis

Completed· Biogen logo

Biogen·Phase 3·NCT01462318·133 enrolled

Head and Neck Cancer1 trial

A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer

Completed·BBrooklyn ImmunoTherapeutics, LLC·Phase 2·NCT00210470·27 enrolled

Growth1 trial

Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis

Completed·FFaculdade de Ciências Médicas da Santa Casa de São Paulo··NCT01389401·36 enrolled

Elderly1 trial

GSK1325756 Relative Bioavailability Study in Healthy Elderly Subjects

Completed· GSK logo

GSK·Phase 1·NCT03457727·40 enrolled

Drug1 trial

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT02182336·23 enrolled

Systemic Inflammation1 trial

Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults

Completed·TThe University of Texas Health Science Center at San Antonio·Phase 1·NCT02844621·25 enrolled

Quality of Life1 trial

Quality of Life Validation in Laryngitis

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00641264·90 enrolled

Outcome1 trial

Omeprazole and Reflux Disease - Improvement of Clinical Outcome by Genotype-adjusted Dosing

Terminated·MMatthias Schwab·Phase 4·NCT00537732·68 enrolled

Glaucoma1 trial

Evaluation of Omeprazole Effect on Glaucoma

Unknown status·SShahid Beheshti University of Medical Sciences·Phase 1·NCT01000220

Randomized Controlled Trial1 trial

The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease

Completed·TTorax Medical Incorporated·Phase 4·NCT02505945·152 enrolled

Impaired Renal Function1 trial

A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)

Completed· Merck & Co. logo

Merck & Co.·Phase 1·NCT01275170·49 enrolled

Hypoalbuminemia1 trial

The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia

Completed·NNational Cheng-Kung University Hospital·Phase 4·NCT01822600·91 enrolled

Cystic Fibrosis1 trial

Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)

Completed·—·Phase 2·NCT03551691·19 enrolled

Crohn's Disease1 trial

Evaluation of the Efficacy of Local Budesonide Treatment in Children with Crohn's Disease Located in the Esophagus And/or Stomach And/or Duodenum

Enrolling by invitation·MMedical University of Warsaw·Phase 2/3·NCT06719622·114 enrolled

Chronic Rhinosinusitis1 trial

Omeprazole 20 mg in Patients With Laryngopharyngeal reﬂux and Comorbid Chronic Rhinosinusitis

Completed·—·Phase 4·NCT03086070·60 enrolled

Type 1 Diabetes1 trial

The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients

Withdrawn·PPerle Bioscience, Inc.·Phase 3·NCT01762644

Dysphagia1 trial

The Role of HRM and Specific Biomarkers of Inflammation in the Diagnosis of Patients With Dysphagia and Suspected EoE

Unknown status·WWroclaw Medical University··NCT04803162·58 enrolled

Gastroparesis1 trial

Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis

Completed·UUniversity of Louisville·Phase 4·NCT00492622·12 enrolled

Prostate Cancer1 trial

Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer

Recruiting·WWake Forest University Health Sciences·Phase 2·NCT04337580·50 enrolled

Heartburn1 trial

Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036)

Completed· Bayer logo

Bayer·Phase 4·NCT01587885·48 enrolled

Atorvastatin1 trial

Study on the Effect of Atorvastatin Co-administered With Omeprazole on Statin Lactone

Recruiting·NNational University Hospital, Singapore·Phase 4·NCT06690164·78 enrolled

Caffeine1 trial

A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants

Completed· Pfizer logo

Pfizer·Phase 1·NCT05067439·26 enrolled

Colonization1 trial

Gastric Acid Suppression and Probiotic Colonization

Completed·SStanford University·Phase 4·NCT03327051·39 enrolled

Gastric Ulcer1 trial

Healing Effects of Rebamipide and Omeprazole in Helicobacter Pylori-positive Gastric Ulcer After Eradication Therapy

Completed·KKorea Otsuka International Asia Arab·Phase 4·NCT00272467·132 enrolled

Antibody1 trial

Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM

Withdrawn·TTiziana Life Sciences LTD·Phase 2·NCT03291249

Medication1 trial

Effect of Acid Suppression Medication on Pediatric Microbiome

Terminated·—·N/A·NCT02016820·7 enrolled

Granuloma1 trial

Efficacy Study of Botulinum Toxin (BOTOX) Injections to Treat Vocal Fold Granulomas

Withdrawn·—·Phase 2·NCT01678053

Ulcerative Colitis1 trial

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

Terminated· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT03358706·28 enrolled

Trial1 trial

The Mechanism Versus PPI Trial

Recruiting·UUniversity of California, San Diego·Phase 4·NCT06999577·160 enrolled

Breast Disease1 trial

Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease

Not yet recruiting·NNational University Hospital, Singapore·Phase 4·NCT06943482·40 enrolled

Morbid Obesity1 trial

Study to Compare the Bioavailability of Omeprazole 20 mg Before and After Undergoing Surgery for Morbid Obesity

Completed·EEmilio Vargas Castrillón·Phase 4·NCT03378960·43 enrolled

Female1 trial

A Study of LY3484356 in Healthy Female Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT04840888·82 enrolled

Anemia1 trial

Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC

Unknown status·SSoroka University Medical Center·Phase 4·NCT01795794·12 enrolled

Type 2 Diabetes Mellitus1 trial

A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus

Completed· Pfizer logo

Pfizer·Phase 1·NCT06279234·50 enrolled

Phase 11 trial

A Phase 1 Study to Examine the Pharmacodynamics of Different AZD1722 Formulations

Completed·AArdelyx·Phase 1·NCT02249936·18 enrolled

Unspecified10 trials

Relative Bioavailability Study of CC-292

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 1·NCT02433457·24 enrolled

Optimal Dosing of Omeprazole in Neonates

Completed·AAssistance Publique - Hôpitaux de Paris·Phase 2·NCT01657578·55 enrolled

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Completed· Boehringer Ingelheim logo

Boehringer Ingelheim·Phase 1·NCT02243553·34 enrolled

Show 7 more trials

Effect of Omeprazole on PK of Fluzoparib in Healthy Male Subjects

Completed·JJiangsu HengRui Medicine Co., Ltd.·Phase 1·NCT04108676·16 enrolled

Prilosec Bioequivalence Study in Healthy Volunteers

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT01921920·54 enrolled

Development of Minidose Inje Cocktail Method for Simultaneous Evaluating Five Cytochrome P450 Isoforms in Human

Completed·IInje University·Phase 1·NCT01570569·26 enrolled

Bioequivalence Study of 20 mg Omeprazole Capsules in Indonesia Healthy Subject

Completed·PPT Kalbe Farma Tbk·N/A·NCT05849883·36 enrolled

Effect of a Proton Pump Inhibitor on Gleevec® in Healthy Volunteers

Completed·UUniversity of Pittsburgh·Phase 1·NCT00446004·15 enrolled

AZD2066 Cocktail Study

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00930306·15 enrolled

A Two Week Nitazoxanidebased Quadruple Regimen

Unknown status·TTanta University·Phase 3·NCT02621359·100 enrolled

Regulatory

FDA Approval Timeline[5]

Oct 5, 1995

PRILOSEC

NDA NDA019810

Jun 20, 2003

PRILOSEC OTC

NDA NDA021229

Dec 4, 2007

OMEPRAZOLE

NDA NDA022032

Mar 20, 2008

PRILOSEC

NDA NDA022056

Jul 5, 2017

OMEPRAZOLE

NDA NDA209400

Sources

References

[1]
ClinicalTrials.gov — 276 trial records for Omeprazole. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Prilosec drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — Omeprazole compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for Omeprazole. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA209400). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Prilosec. U.S. Food & Drug Administration.
[7]
SEC EDGAR — Dexcel Pharma Technologies Ltd. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Potassium-Transporting Atpase Inhibitor[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: DDexcel Pharma Technologies Ltd.

Patent Landscape[6]

Patent Cliff

Jan 31, 2030

Earliest patent expiration — generic entry possible after this date

Patent #Expires

12599565Jan 31, 2030

10835488Dec 8, 2036