VivoSeq
Other

Toothache

20

Pipeline Programs↗

0

Active Trials↗

11

Companies Involved↗

Toothache is an emerging landscape with 20 programs across 11 companies. The most active players are Daewon Pharmaceutical Co., Ltd., Haisco Pharmaceutical Group Co., Ltd., Kenvue Brands. 13 therapies are approved with 4 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

46/100

Pipeline Velocity

6/100

Mech. Concentration

47/100

Completion Rate

83/100

Attrition Rate

17/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

Daewon Pharmaceutical Co., Ltd. logo

Daewon Pharmaceutical Co., Ltd.

1 program

Phase 3Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.

1 program

Phase 3K

Kenvue Brands

2 programs

ApprovedPfizer logo

Pfizer

1 program

ApprovedP

Protega

1 program

ApprovedBoehringer Ingelheim logo

Boehringer Ingelheim

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

6

clinical trials

Completed5 · 83%
Terminated1 · 17%

Clinical Trials

Trial Activity

6 trials

The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache
Completed·—·Phase 4·NCT00574015·18 enrolled
Benzocaine Gel Toothache Dose-Response Study
Completed·Pfizer logoPfizer·Phase 4·NCT00474175·577 enrolled
Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Acute Toothache Patients After Teeth Extraction Surgery
Completed·Daewon Pharmaceutical Co., Ltd. logoDaewon Pharmaceutical Co., Ltd.·Phase 3·NCT01920386·240 enrolled
Effect of Buffered Numbing Solution on Patients With Toothaches
Completed·OOhio State University·N/A·NCT01868776·100 enrolled
The Effect of Different Patient Education Methods in Patients Presenting to an Endodontic Clinic With Toothache and the Feasibility of an AI-Assisted Complaint Summary
Completed·CCukurova University·Preclinical·NCT07698847·120 enrolled
Percocet vs. Bupivicaine for Toothaches in the ED
Terminated·SStony Brook University·Phase 2·NCT02862691·2 enrolled

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)