allo-APZ2-CVU

Phase 3Small molecule

RRHEACELL GmbH & Co. KG

allo-APZ2-CVU is one of 2 small molecule programs targeting Mesenchymal Stromal Cells. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Mesenchymal Stromal CellsActive, not recruiting

Mesenchymal Stromal CellsPhase 3

Active, not recruiting

Competition

Competitive Landscape

2 competitors in Mesenchymal Stromal Cells

#DrugCompanyPhaseTrials

allo-APZ2-CVU

RRHEACELL GmbH & Co. KG

Phase 3

2 2

Imsc

RRuijin Hospital

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2027

Phase 3Active, not recruiting

Mesenchymal Stromal Cells

NCT06489028

Clinical

Trials by Indication[1]

Mesenchymal Stromal Cells2 trials

Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase IIb)

Completed·RRHEACELL GmbH & Co. KG·Phase 2·NCT04971161·159 enrolled

Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Therapy-resistant CVU (Phase III)

Active, not recruiting·RRHEACELL GmbH & Co. KG·Phase 3·NCT06489028·250 enrolled

Stem Cells1 trial

Allogeneic ABCB5-positive Stem Cells for Treatment of CVU

Completed·RRHEACELL GmbH & Co. KG·Phase 1/2·NCT03257098·31 enrolled

Sources

References

[1]
ClinicalTrials.gov — 3 trial records for allo-APZ2-CVU. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — allo-APZ2-CVU compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for allo-APZ2-CVU. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — RHEACELL GmbH & Co. KG company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: RRHEACELL GmbH & Co. KG

allo-APZ2-CVU

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2027

Trials by Indication[1]

Mesenchymal Stromal Cells2 trials

Stem Cells1 trial

References

Drug Info

Quick Facts

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