Aloe Vera

Phase 2Small molecule

GGovernment Dental College and Research Institute, Bangalore

Aloe Vera is one of 33 small molecule programs targeting Proctosigmoiditis. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

ProctosigmoiditisActive, not recruiting

MPANot yet recruiting

ProctosigmoiditisPreclinical

Active, not recruiting

MPAPhase 2

Not yet recruiting

Competition

Competitive Landscape

52 competitors in MPA

#DrugCompanyPhaseTrials

Flomax

Sanofi

Approved

4 2

Repatha

Amgen

Approved

2 3

Myrbetriq

Astellas

Approved

1 4

Tremfya

Johnson & Johnson

Approved

1 5

Jardiance

Boehringer Ingelheim

Approved

2 6

Rituxan

Roche

Phase 3

3 7

Activella

Eli Lilly

Phase 3

2 8

Epsom Salt

FFresenius Kabi USA, LLC

Phase 3

3 9

Nitrostat

VViatris Specialty LLC

Phase 2

2 10

Obicetrapib

NNewAmsterdam Pharma

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Chronic Periodontitis2 trials

Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT03204097·90 enrolled

Local Drug Delivery of Aloe Vera Gel in Chronic Periodontitis

Completed·—·Phase 2/3·NCT02462993·12 enrolled

Oral Mucositis2 trials

Comparison Between the Effect of Aloe Vera and Benzydamine Hydrochloride Mouth Gel on Prevention of Pain and Progression of Radiation-induced Oral Mucositis

Completed·MMinia University·Phase 1/2·NCT06862817·30 enrolled

Evaluation of the Efficacy of Aloe-Vera el Versus Bezydamine Hydrochloride in the Prevention of Radiation Induced Oral Mucositis A Randamized Controlled Clinical Trial

Completed·OOctober 6 University·Phase 4·NCT06879366·40 enrolled

Type 2 Diabetes Mellitus1 trial

Aloe Vera in Chronic Periodontitis With Type 2 Diabetes Mellitus

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT02386020·60 enrolled

MPA1 trial

Comparing of Sesame Oil, Nitroglycerin Ointment, and Aloe Vera Gel

Not yet recruiting·UUniversity of Basrah·Phase 2·NCT07346677·190 enrolled

Emergency Department Patient1 trial

A Trial of Topical Aloe Vera Gel in Emergency Department Patients Presenting With Simple Traumatic Wounds

Withdrawn·NNHS Lothian·Phase 1/2·NCT02819817

3 more indications

Proctosigmoiditis1 trial

RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ENEMA ALOE VERA GEL IN ACTIVE ULCERATIVE PROCTOSIGMOIDITIS.

Completed·OOspedale Sandro Pertini, Roma·N/A·NCT04753775·44 enrolled

Trial1 trial

Trial Comparing Best Supportive Care to Aloe Vera Gel

Completed·MMarilia Medicine School·Phase 3·NCT00876642·137 enrolled

Unspecified1 trial

Effect of Aloe Vera Gel as an Intra Canal Medicament

Completed·IIslamabad Medical and Dental College·N/A·NCT06243601·60 enrolled

Sources

References

[1]
ClinicalTrials.gov — 10 trial records for Aloe Vera. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Aloe Vera compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Aloe Vera. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Government Dental College and Research Institute, Bangalore company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: GGovernment Dental College and Research Institute, Bangalore

Aloe Vera

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Chronic Periodontitis2 trials

Oral Mucositis2 trials

Type 2 Diabetes Mellitus1 trial

MPA1 trial

Emergency Department Patient1 trial

Proctosigmoiditis1 trial

Trial1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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