Azithromycin IV

Phase 3Small molecule

Azithromycin IV is one of 149 small molecule programs targeting Pelvic Inflammatory Disease. It is currently in Phase 3.

Indications

Total Trials

Active Trials

148

Competitors

Pipeline

Status by Indication[3][1]

Indication

Pelvic Inflammatory DiseaseActive, not recruiting

Plasmodium Falciparum MalariaActive, not recruiting

MalariaActive, not recruiting

PneumoniaActive, not recruiting

Acute BronchitisActive, not recruiting

Chronic BronchitisActive, not recruiting

Maxillary SinusitisActive, not recruiting

PharyngitisActive, not recruiting

Pelvic Inflammatory DiseasePreclinical

Active, not recruiting

Plasmodium Falciparum MalariaPhase 2

Active, not recruiting

MalariaPhase 2/Phase 3

Active, not recruiting

PneumoniaPhase 3

Active, not recruiting

Acute BronchitisPhase 3

Active, not recruiting

Chronic BronchitisPhase 3

Active, not recruiting

Maxillary SinusitisPreclinical

Active, not recruiting

PharyngitisPhase 3

Active, not recruiting

Competition

Competitive Landscape

547 competitors in Pneumonia

#DrugCompanyPhaseTrials

Azithromycin IV

Pfizer

Phase 3

4 2

Jakafi

Incyte

Preclinical

1 3

Primaquine

Sanofi

Preclinical

1 4

Innohep

Alnylam Pharmaceuticals

Preclinical

1 5

Neutrexin

WWest Japan Thoracic Oncology Group

Preclinical

12 6

Virazole

CConrado Roberto Hoffmann Filho

Preclinical

2 7

Advil

KKenvue Brands

Preclinical

2 8

Retrovir

BBp Consulting, Inc

Preclinical

2 9

Primsol

CConrado Roberto Hoffmann Filho

Preclinical

2 10

Prograf

VVeloxis Pharmaceuticals

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Azithromycin4 trials

A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine

Completed· Pfizer logo

Pfizer·Phase 1·NCT00844207·40 enrolled

Bioequivalence (BE) Study Comparing Azithromycin 250 mg Tablet Manufactured in China and in the United States

Completed· Pfizer logo

Pfizer·Phase 1·NCT03353480·66 enrolled

A Single, High-Dose Azithromycin Extended Release (60 mg/kg) Compared With 10 Days of High-Dose Amoxicillin Clavulanate in Children With Ear Infections at High Risk of Persistent/Recurrent Ear Infections

Completed· Pfizer logo

Pfizer·Phase 3·NCT00643292·902 enrolled

Show 1 more trial

Special Investigation Of Azithromycin IV For Legionnaires' Disease (Regulatory Post Marketing Commitment Plan)

Completed· Pfizer logo

Pfizer··NCT01784770·21 enrolled

Pneumonia4 trials

A Trial Of Azithromycin SR For The Treatment Of Mild To Moderate Community Acquired Pneumonia In Japanese Adults

Completed· Pfizer logo

Pfizer·Phase 3·NCT00360295·153 enrolled

Non-Interventional Open Label Prospective Observational Comparative Study On Evaluation Of Compliance Of The Empiric Treatment With Azithromycin SR Versus Amoxiclav 1000 Mg In Adult Patients With Mild To Moderate Community Acquired Pneumonia

Terminated· Pfizer logo

Pfizer··NCT01032694·30 enrolled

Azithromycin Microspheres in Patients With Low Risk Community Acquired Pneumonia

Completed· Pfizer logo

Pfizer·Phase 3·NCT00140023·47 enrolled

Show 1 more trial

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Clarithromycin Extended Release for the Treatment of Pneumonia in Adult Patients

Completed· Pfizer logo

Pfizer·Phase 3·NCT00643227·504 enrolled

Malaria3 trials

Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa

Terminated· Pfizer logo

Pfizer·Phase 3·NCT01103063·2,891 enrolled

Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa

Completed· Pfizer logo

Pfizer·Phase 2/3·NCT00677833·361 enrolled

Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.

Completed· Pfizer logo

Pfizer·Phase 3·NCT00367653·397 enrolled

Double-blind3 trials

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Sinus Infections in Adults

Completed· Pfizer logo

Pfizer·Phase 3·NCT00643409·541 enrolled

A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults

Completed· Pfizer logo

Pfizer·Phase 3·NCT00644293·598 enrolled

A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children

Completed· Pfizer logo

Pfizer·Phase 3·NCT00643149·693 enrolled

Chronic Bronchitis2 trials

A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis (AECB)

Completed· Pfizer logo

Pfizer·Phase 3·NCT00254566·398 enrolled

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Acute Symptoms of Chronic Bronchitis

Completed· Pfizer logo

Pfizer·Phase 3·NCT00644449·551 enrolled

10 more indications

Pregnant Women1 trial

Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa

Terminated· Pfizer logo

Pfizer·Phase 3·NCT01103713·168 enrolled

Adult Subject1 trial

A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects

Completed· Pfizer logo

Pfizer·Phase 1·NCT01100060·40 enrolled

Clinical Trial1 trial

A Randomized, Open Label, Clinical Trial of the Pharmacokinetics of Azithromycin Following a Single Dose of Azithromycin Sustained Release (2 Gram) or Commercial Azithromycin Tablet (500 mg) to Cancer Patients That Require Lung Surgery

Completed· Pfizer logo

Pfizer·Phase 2·NCT00644176·66 enrolled

Maxillary Sinusitis1 trial

Non-Interventional Open Label Prospective Comparative Observational Study Of Evaluation Of Compliance In The Empiric Treatment With Azithromycin SR Versus Amoxiclav 1000 Mg In Adult Patients With Of Acute Bacterial Maxillary Sinusitis

Completed· Pfizer logo

Pfizer··NCT01032174·123 enrolled

Pharyngitis1 trial

A Trial Of Azithromycin SR For The Treatment Of Laryngopharyngitis or Tonsillitis or Acute Bacterial Rhinosinusitis

Completed· Pfizer logo

Pfizer·Phase 3·NCT00393835·99 enrolled

Acute bronchitis1 trial

A Trial Of Azithromycin SR For The Treatment Of Acute Bronchitis And Secondary Infection Of Chronic Respiratory Diseases

Completed· Pfizer logo

Pfizer·Phase 3·NCT00360464·64 enrolled

Plasmodium falciparum malaria1 trial

A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria

Completed· Pfizer logo

Pfizer·Phase 2·NCT00282919·110 enrolled

Efficacy and Safety1 trial

Efficacy And Safety Of Azithromycin SR Compared With Minocycline In Acne

Terminated· Pfizer logo

Pfizer·Phase 3·NCT00392223·118 enrolled

Pelvic Inflammatory Disease1 trial

Drug Use Investigation Of Azithromycin IV For Pneumonia Or Pelvic Inflammatory Disease (Regulatory Post Marketing Commitment Plan)

Completed· Pfizer logo

Pfizer··NCT01671280·403 enrolled

Unspecified1 trial

Zithromax-SR 2g, Special Investigation (Regulatory Post Marketing Commitment Plan)

Completed· Pfizer logo

Pfizer··NCT00998309·502 enrolled

Sources

References

[1]
ClinicalTrials.gov — 26 trial records for Azithromycin IV. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Azithromycin IV compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Azithromycin IV. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Pfizer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: Pfizer

Azithromycin IV

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Azithromycin4 trials

Pneumonia4 trials

Malaria3 trials

Double-blind3 trials

Chronic Bronchitis2 trials

Pregnant Women1 trial

Adult Subject1 trial

Clinical Trial1 trial

Maxillary Sinusitis1 trial

Pharyngitis1 trial

Acute bronchitis1 trial

Plasmodium falciparum malaria1 trial

Efficacy and Safety1 trial

Pelvic Inflammatory Disease1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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