BGB-3111

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

45 competitors in TED

#DrugCompanyPhaseTrials

1

Farxiga

AstraZeneca

Approved

22

Scemblix

Novartis

Approved

13

Alecensa

Roche

Approved

14

Rituxan

Roche

Phase 3

25

Calquence

AstraZeneca

Phase 3

26

Medrol

Pfizer

Phase 3

27

Golytely

Bayer

Phase 3

18

Treanda

AAzurity Pharmaceuticals

Phase 3

19

Fludara

Sanofi

Phase 2

310

Eliquis

Bristol-Myers Squibb

Phase 2

3Show 28 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Cardiac Repolarization1 trial

A Two-Part Phase 1 Study to Investigate the Safety and Tolerability of Supratherapeutic Dose of Zanubrutinib and Effect of Zanubrutinib on Cardiac Repolarization in Healthy Subjects

Completed·BeiGene·Phase 1·NCT03432884·40 enrolled

TED1 trial

Sonrotoclax, Zanubrutinib and CD20mab in Untreated MCL Patients

Recruiting·TTianjin Medical University Cancer Institute and Hospital·Phase 2·NCT06463691·30 enrolled

Absorption1 trial

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-BGB-3111 in Healthy Males

Completed·BeiGene·Phase 1·NCT04163783·6 enrolled

Interaction1 trial

A Pharmacokinetic Study to Assess Drug-drug Interaction Between Zanubrutinib and a Cocktail of Substrates in Healthy Subjects

Completed·BeiGene·Phase 1·NCT03561298·18 enrolled

Macroglobulinemia1 trial

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)

Completed·BeiGene·Phase 3·NCT03053440·201 enrolled

1 more indication

Phase 11 trial

Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects

Completed·BeiGene·Phase 1·NCT03301181·40 enrolled

Details

Drug Info

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