Chemotherapy: fludarabine (FLU)

Phase 1Small molecule

Chemotherapy: fludarabine (FLU) is one of 3 small molecule programs targeting Progressive Multiple Sclerosis. It is currently in Phase 1.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Progressive Multiple SclerosisActive, not recruiting

Progressive Multiple SclerosisPhase 1

Active, not recruiting

Competition

Competitive Landscape

4 competitors in Progressive Multiple Sclerosis

#DrugCompanyPhaseTrials

Ocrevus

Roche

Phase 2

1 2

Rapcabtagene Autoleucel

Novartis

Preclinical

1 3

Chemotherapy: fludarabine (FLU)

BBruce Cree

Phase 1

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 1Active, not recruiting

Progressive Multiple Sclerosis

NCT06451159

Clinical

Trials by Indication[1]

Progressive Multiple Sclerosis1 trial

Phase 1, Open-Label, Single Center Study of KYV-101, an Autologous Fully-Human Anti-CD19 Chimeric Antigen Receptor T Cell (CD19 CAR T) Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis

Active, not recruiting·BBruce Cree·Phase 1·NCT06451159·10 enrolled

Sources

References

[1]
ClinicalTrials.gov — 1 trial record for Chemotherapy: fludarabine (FLU). U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Chemotherapy: fludarabine (FLU) compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Chemotherapy: fludarabine (FLU). EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Bruce Cree company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 1[1]
Company: BBruce Cree

Chemotherapy: fludarabine (FLU)

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Trials by Indication[1]

Progressive Multiple Sclerosis1 trial

References

Drug Info

Quick Facts

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