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collagenase
Preclinical
Protein / enzyme
M
Matrizyme Pharma Corporation
1
Indications
15
Total Trials
0
Active Trials
0
Competitors
Pipeline
Status by Indication
[3]
[1]
Indication
Preclinical
Phase 1
Phase 2
Phase 3
Approved
Pressure Ulcers
Terminated
Preclinical
Phase 1
Phase 2
Phase 3
Approved
Pressure Ulcers
Preclinical
Terminated
Clinical
Trials by Indication
[1]
Dupuytren's Disease
2 trials
Phase II Randomized Study of Collagenase in Patients With Residual Type Dupuytren's Disease
Completed
·
S
State University of New York
·
Phase 2
·
NCT00004409
·
36 enrolled
Phase III Randomized Study of Collagenase in Patients With Residual Stage Dupuytren's Disease
Completed
·
S
State University of New York
·
Phase 3
·
NCT00014742
·
72 enrolled
Treatment
2 trials
Collagenase in the Treatment of Cellulite
Unknown status
·
S
Stony Brook University
·
Phase 2
·
NCT00261144
·
20 enrolled
Collagenase in the Treatment of Zone II Flexor Tendon Adhesions in the Hand
Completed
·
S
Stony Brook University
·
Phase 1/2
·
NCT00261209
·
3 enrolled
Pressure Ulcers
2 trials
Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers
Terminated
·
L
Louisiana State University Health Sciences Center Shreveport
·
N/A
·
NCT01208220
·
2 enrolled
Evaluate the Noninferiority of Medicines Treating Uninfected Pressure Ulcers.
Withdrawn
·
C
Cristália Produtos Químicos Farmacêuticos Ltda.
·
Phase 3
·
NCT02004626
Occlusion
2 trials
Collagenase Total Occlusion-1 Trial
Completed
·
S
Sunnybrook Health Sciences Centre
·
Phase 1
·
NCT01271335
·
28 enrolled
Total Occlusion Study in Coronary Arteries - 5
Completed
·
M
Matrizyme Pharma Corporation
·
Phase 2
·
NCT01753180
·
76 enrolled
Negative Pressure Wound Therapy
1 trial
Negative Pressure Wound Therapy With Instillation of Saline Solution Versus Collagenase Ointment in Full-thickness Wounds
Terminated
·
K
KCI USA, Inc
·
N/A
·
NCT03722485
·
44 enrolled
6 more indications
Cutaneous Ulcer
1 trial
Non-inferiority Clinic of Kollagenase® Compared Iruxol® in Treatment of Cutaneous Ulcers
Suspended
·
A
Azidus Brasil
·
Phase 2/3
·
NCT00701974
·
66 enrolled
Medication
1 trial
EZCast-DFU Study With Portal for Application of Topical Medications
Completed
·
U
University of Miami
·
Phase 1
·
NCT02131961
·
4 enrolled
Trial
1 trial
Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's
Completed
·
M
McMaster University
·
Phase 3
·
NCT02725528
·
22 enrolled
Chronic
1 trial
Unripe Banana Peel Powder and Lemongrass Oil in Chronic Ulcer
Completed
·
U
Universidade do Vale do Sapucai
·
Phase 1
·
NCT04963829
·
25 enrolled
Wound
1 trial
MEDIHONEY® Gel Versus Collagenase for Wound Debridement
Terminated
·
I
Integra LifeSciences Corporation
·
N/A
·
NCT02482948
·
10 enrolled
Frozen Shoulder
1 trial
Collagenase in the Treatment of Adhesive Capsulitis (Frozen Shoulder)
Withdrawn
·
S
Stony Brook University
·
Phase 2
·
NCT00261196
Sources
References
[1]
ClinicalTrials.gov
—
15 trial records for collagenase. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL
—
collagenase compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform
—
Drug–disease associations for collagenase. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR
—
Matrizyme Pharma Corporation company filings. U.S. Securities and Exchange Commission.
Details
Drug Info
Quick Facts
Modality
Protein / enzyme
[2]
Highest Phase
Preclinical
[1]
Company
M
Matrizyme Pharma Corporation
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