Controlled Human Malaria Infection

PreclinicalBiologic

Controlled Human Malaria Infection is one of 5 biologic programs targeting Plasmodium Falciparum. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Plasmodium FalciparumCompleted

Plasmodium FalciparumPreclinical

Completed

Competition

Competitive Landscape

5 competitors in Plasmodium Falciparum

#DrugCompanyPhaseTrials

Atovaquone/proguanil

Pfizer

Preclinical

2 2

Chloroquine Prophylaxis

RRadboud University Medical Center

Preclinical

2 3

Plasmodium Falciparum Challenge

RRadboud University Medical Center

Preclinical

1 4

Controlled Human Malaria Infection

RRadboud University Medical Center

Preclinical

2 5

Malarone

Medicines for Malaria Venture

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Plasmodium Falciparum2 trials

Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis

Completed·RRadboud University Medical Center·N/A·NCT02080026·15 enrolled

Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis

Completed·RRadboud University Medical Center·N/A·NCT01422954·20 enrolled

Malaria (Plasmodium Falciparum)1 trial

Phase I Trial for the Establishment of Controlled Human Malaria Infection by Bites of Plasmodium Falciparum-infected Anopheles Gambiae in Lambaréné

Completed·CCentre de Recherche Médicale de Lambaréné·Phase 1·NCT07816497·20 enrolled

Sources

References

[1]
ClinicalTrials.gov — 3 trial records for Controlled Human Malaria Infection. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Controlled Human Malaria Infection compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Controlled Human Malaria Infection. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Radboud University Medical Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Biologic[2]
Highest Phase: Preclinical[1]
Company: RRadboud University Medical Center

Controlled Human Malaria Infection

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Plasmodium Falciparum2 trials

Malaria (Plasmodium Falciparum)1 trial

References

Drug Info

Quick Facts

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