Doxycyclin

Phase 3Small molecule

TTanta University

Doxycyclin is one of 40 small molecule programs targeting Granuloma. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

GranulomaActive, not recruiting

Bacterial VaginosisNot yet recruiting

Breast CancerRecruiting

GranulomaPreclinical

Active, not recruiting

Bacterial VaginosisPhase 3

Not yet recruiting

Breast CancerPhase 2

Recruiting

Competition

Competitive Landscape

744 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Doxycyclin

TTanta University

Phase 3

1 2

Methylthioninium Chloride

PProvepharm SAS

Preclinical

3 3

Ablavar

LLantheus Medical Imaging

Preclinical

2 4

Naltrexone/bupropion

Novo Nordisk

Preclinical

1 5

Motexafin Gadolinium

PPharmacyclics LLC.

Preclinical

1 6

Sertraline ODT

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

1 7

Liposomal Irinotecan and Apatinib

SSecond Affiliated Hospital, School of Medicine, Zhejiang University

Preclinical

1 8

Tetracycline Hydrochloride

EEuropean Organisation for Research and Treatment of Cancer - EORTC

Preclinical

1 9

Trastuzuma

FFudan University

Preclinical

1 10

Atracurium Besylate

MMansoura University

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2028

Phase 2/3Not yet recruiting

Combination Therapy

NCT05897034

Q4 2028

Phase 2Recruiting

Breast Cancer

NCT06452394

Q2 2029

Phase 3Not yet recruiting

Bacterial Vaginosis

NCT06349122

Clinical

Trials by Indication[1]

Prevention1 trial

Weekly Doxycycline DOT for STI Prevention Among Cisgender Women Taking HIV PrEP in Kisumu, Kenya

Completed·UUniversity of Washington·Phase 4·NCT06582966·60 enrolled

Combination Therapy1 trial

Combination Therapy Between Doxycycline, Pentoxifylline, and Nitazoxanide in Sexually Active Men

Not yet recruiting·TTanta University·Phase 2/3·NCT05897034·100 enrolled

Granuloma1 trial

Comparison Of Doxycycline And Common Salt For Treatment Of Umbilical Granuloma: A Randomised Control Trial

Completed·SShaheed Zulfiqar Ali Bhutto Medical University·N/A·NCT05545462·196 enrolled

Azithromycin1 trial

Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoea

Completed·—·Phase 4·NCT06090565·161 enrolled

Meibomian Gland Dysfunction1 trial

Comparison Between Continuous and Pulsed Oral Doxycycline Treatment Protocols for Refractory Meibomian Gland Dysfunction

Completed·UUniversity of Milan··NCT06520007·65 enrolled

6 more indications

CLE1 trial

Rickettsia Clearance Study

Recruiting·—·Phase 2/3·NCT05972772·72 enrolled

Breast Cancer1 trial

NEODOXy: Targeting Breast Cancer Stem Cells With Doxycycline

Recruiting·SSwiss Cancer Institute·Phase 2·NCT06452394·50 enrolled

COVID-191 trial

OD-doxy-PNV-COVID-19 Old Drug " DOXY " for Prevention of New Virus " COVID-19 "

Completed·HHedi Gharsallah·Phase 3·NCT04584567·194 enrolled

Diabetes Mellitus, Type 21 trial

Doxycycline in Combination With Sitagliptin on the Glycemic and Cardiac Indices in Patients With Type 2 Diabetes Mellitus

Completed·MMostafa Bahaa·Preclinical·NCT06329882·60 enrolled

Bacterial Vaginosis1 trial

Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth: A Multicentre, Randomized Study (AUTOP 2)

Not yet recruiting·AAssistance Publique Hopitaux De Marseille·Phase 3·NCT06349122·1,794 enrolled

Unspecified1 trial

A Two Week Nitazoxanidebased Quadruple Regimen

Unknown status·TTanta University·Phase 3·NCT02621359·100 enrolled

Sources

References

[1]
ClinicalTrials.gov — 11 trial records for Doxycyclin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Doxycyclin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Doxycyclin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Tanta University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: TTanta University

Doxycyclin

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2028

Q4 2028

Q2 2029

Trials by Indication[1]

Prevention1 trial

Combination Therapy1 trial

Granuloma1 trial

Azithromycin1 trial

Meibomian Gland Dysfunction1 trial

CLE1 trial

Breast Cancer1 trial

COVID-191 trial

Diabetes Mellitus, Type 21 trial

Bacterial Vaginosis1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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