Escherichia coli Endotoxin

PreclinicalSmall molecule

MMedical University of Vienna

Escherichia coli Endotoxin is one of 36 small molecule programs targeting Tics. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

TicsCompleted

VasoconstrictionCompleted

Renal Blood FlowUnknown status

TicsPreclinical

Completed

VasoconstrictionPreclinical

Completed

Renal Blood FlowPreclinical

Unknown status

Competition

Competitive Landscape

114 competitors in Tics

#DrugCompanyPhaseTrials

Sodium Valproate

AstraZeneca

Phase 3

1 2

Priftin

Sanofi

Phase 2

1 3

Nydrazid

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 2

4 4

Duvyzat

Italfarmaco

Phase 2

2 5

Dilaudid

RRhodes Pharmaceuticals, L.P.

Phase 2

1 6

CAB LA

GSK

Phase 2

1 7

Abexinostat

XXynomic Pharmaceuticals, Inc.

Phase 2

1 8

Anaprazole

SSihuan Pharmaceutical Holdings Group Ltd.

Phase 3

1 9

Cocaine Hydrochloride

NNoden Pharma

Phase 3

1 10

Dostinex

Pfizer

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Vasoconstriction2 trials

Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans

Completed·MMedical University of Vienna·N/A·NCT02221089·40 enrolled

Effect of Antioxidants on Oxygen Induced Vasoconstriction in Lipopolysaccharide (LPS) Induced Inflammatory Model in Humans

Completed·MMedical University of Vienna·N/A·NCT00914576·40 enrolled

Tics1 trial

Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls

Completed·RRigshospitalet, Denmark·N/A·NCT00412906·48 enrolled

Renal Blood Flow1 trial

Study of Renal Blood Flow During Human Endotoxemia

Unknown status·RRigshospitalet, Denmark·N/A·NCT00413465·32 enrolled

Endothelial Function1 trial

Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans.

Completed·MMedical University of Vienna·Phase 4·NCT00431691·22 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for Escherichia coli Endotoxin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Escherichia coli Endotoxin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Escherichia coli Endotoxin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Medical University of Vienna company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: MMedical University of Vienna

Escherichia coli Endotoxin

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Vasoconstriction2 trials

Tics1 trial

Renal Blood Flow1 trial

Endothelial Function1 trial

References

Drug Info

Quick Facts

Related News