Dilaudid

(Hydromorphone)

ApprovedSmall molecule

Hydromorphone is a strong opioid pain reliever used to treat moderate to severe pain, and is also sometimes used to help manage severe coughs.[2] Dilaudid is currently approved and in use across 35 indications[4].[1]

Dilaudid is one of 473 small molecule programs targeting Mucositis. It is currently in Approved.

Indications

103

Total Trials

Active Trials

472

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

MucositisApproved

Osteoarthritis, HipApproved

Osteoarthritis, KneeApproved

Chronic PainApproved

Low Back PainApproved

Kidney CancerApproved

Kidney NeoplasmApproved

IleusApproved

Respiratory DepressionActive, not recruiting

FractureRecruiting

MucositisApproved

Approved

Osteoarthritis, HipApproved

Approved

Osteoarthritis, KneeApproved

Approved

Chronic PainApproved

Approved

Low Back PainApproved

Approved

Kidney CancerApproved

Approved

Kidney NeoplasmApproved

Approved

IleusApproved

Approved

Respiratory DepressionPreclinical

Active, not recruiting

FracturePreclinical

Recruiting

Showing 10 of 31 indications

Competition

Competitive Landscape

114 competitors in Tics

#DrugCompanyPhaseTrials

Dilaudid

RRhodes Pharmaceuticals, L.P.

Approved

1 2

Sodium Valproate

AstraZeneca

Phase 3

1 3

Rifadin

Sanofi

Phase 1

26 4

Priftin

Sanofi

Phase 2

1 5

Nydrazid

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 2

4 6

Sporanox

SSebela Pharmaceuticals Development LLC

Phase 1

54 7

Duvyzat

Italfarmaco

Phase 2

2 8

CAB LA

GSK

Phase 2

1 9

Taltz

Eli Lilly

Phase 1

1 10

DTIC-Dome

Bayer

Phase 1

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Phase 2Recruiting

Nephrectomy

NCT05842044

Q4 2026

Phase 1Recruiting

Opioids

NCT05610072

Q1 2027

PreclinicalRecruiting

Fracture

NCT07430345

Phase 2Recruiting

Opioid Withdrawal

NCT05027919

Q3 2027

Recruiting

Anesthesia

NCT03427736

Clinical

Trials by Indication[1]

Cancer Pain5 trials

Study of Opioid Rotation Versus Opioid Escalation in Patients With Moderate to Severe Cancer Pain

Unknown status·GGyeongsang National University Hospital·Phase 3·NCT02084355·136 enrolled

An Efficacy and Safety Study of Hydromorphone Oral Osmotic System (OROS) in Korean Participants With Cancer Pain

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 4·NCT00766831·190 enrolled

Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain

Active, not recruiting·MM.D. Anderson Cancer Center·Phase 4·NCT04296305·84 enrolled

Show 2 more trials

Prospective Longitudinal Observational Study to Evaluate the Clinical Characteristics and Opioids Treatments in Patients With Breakthrough Cancer Pain

Completed· Mario Negri Institute for Pharmacological Research logo

Mario Negri Institute for Pharmacological Research··NCT01946555·150 enrolled

PCA vs Non-PCA Intravenous Hydromorphone Titration for Severe Cancer Pain

Completed·FFujian Cancer Hospital·Phase 3·NCT03375515·214 enrolled

Labor Analgesia4 trials

Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor Analgesia

Completed·MMaternal and Child Health Hospital of Hubei Province·Phase 2·NCT05901441·240 enrolled

Intrathecal Hydromorphone for Labor Analgesia

Terminated·—·N/A·NCT02277782·21 enrolled

Intravenous Remifentanil for Labor Analgesia

Completed·NNanjing Medical University·Phase 4·NCT00710086·1,000 enrolled

Show 1 more trial

Intrathecal Hydromorphone for Labor Analgesia

Completed·EEmory University·Phase 2·NCT01598506·22 enrolled

Intravenous4 trials

Safety Study of Intravenous Hydromorphone Using Incremental 1mg Doses up to 2mg for Adult ED Patients

Completed·MMontefiore Medical Center·Phase 4·NCT00682435·230 enrolled

Comparing Intravenous Hydromorphone to Usual Care

Completed·MMontefiore Medical Center·Phase 4·NCT01429298·350 enrolled

Titration of Intravenous Hydromorphone

Completed·MMontefiore Medical Center·Phase 4·NCT01892709·215 enrolled

Show 1 more trial

Intravenous Hydromorphone for the Treatment of Acute Pain

Recruiting·TThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School·Phase 1/2·NCT06949059·30 enrolled

Post Operative Pain4 trials

Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCA

Completed·UUniversity of Erlangen-Nürnberg Medical School·Phase 4·NCT02483221·50 enrolled

Synergistic Effect of Ibuprofen and Hydromorphone for Postoperative Pain

Completed·SSamsung Medical Center·N/A·NCT02461056·90 enrolled

An Open-label Study of Hydromorphone Oral Solution in Subjects Aged 28 Days to 16 Years for Postoperative Pain

Completed·PPurdue Pharma LP·Phase 4·NCT00465647·116 enrolled

Show 1 more trial

Postoperative Pain Therapy With Hydromorphone Using TCI-PCA

Completed·UUniversity of Erlangen-Nürnberg Medical School·Phase 4·NCT02035709·50 enrolled

Opioid Use Disorder3 trials

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Terminated· AstraZeneca logo

AstraZeneca·Phase 1·NCT06406400·15 enrolled

Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder

Recruiting·UUniversity of British Columbia·Phase 2·NCT04234191·50 enrolled

Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking Buprenorphine

Withdrawn·UUniversity of North Carolina, Chapel Hill·Phase 4·NCT06784180

67 more indications

Anesthesia3 trials

Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery

Recruiting·EEndeavor Health·Phase 4·NCT03893734·140 enrolled

Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

Completed·—·Phase 4·NCT03726268·907 enrolled

Pharmacokinetics of Anesthetics and Analgesics in Children and Adolescent

Recruiting·CChi Dang Hornik··NCT03427736·551 enrolled

Opioid3 trials

Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries

Completed·UUniversity of Alberta·N/A·NCT05375916·80 enrolled

Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals

Completed·WWayne State University··NCT00218361·16 enrolled

Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals

Completed·NNational Institute on Drug Abuse (NIDA)··NCT00218309·16 enrolled

Cesarean Delivery3 trials

Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study

Terminated·—·Phase 4·NCT01943565·29 enrolled

Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal Dose

Completed·MMayo Clinic·Phase 4·NCT02009722·84 enrolled

Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery

Completed·MMayo Clinic·N/A·NCT02789410·134 enrolled

Oxycodone2 trials

Non-analgesic Effects Produced by Equipotent Analgesic Doses of Sufentanil, Hydromorphone, and Oxycodone

Completed·PPeking University People's Hospital·Phase 4·NCT04396587·80 enrolled

Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin)

Completed· Endo Pharmaceuticals logo

Endo Pharmaceuticals·Phase 4·NCT00955110·78 enrolled

Sickle Cell Disease2 trials

Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease

Completed·—·Phase 4·NCT02222246·106 enrolled

Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease

Terminated·—·Phase 3·NCT03933397·328 enrolled

Opioids2 trials

ALK21-004: Single-dose Opiate Challenge of Medisorb® Naltrexone (VIVITROL®) in Adults Who Use Opioids

Completed·AAlkermes, Inc.·Phase 2·NCT01218984·27 enrolled

Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)

Recruiting·WWilliam Stoops·Phase 1·NCT05610072·24 enrolled

Emergency Department Patient2 trials

Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe Pain

Completed·MMontefiore Medical Center·Phase 4·NCT01429285·350 enrolled

IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients

Completed·—·Phase 3·NCT03553498·162 enrolled

Cancer2 trials

Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer

Terminated·MM.D. Anderson Cancer Center·Phase 1·NCT03579446·43 enrolled

A Pharmacokinetic and Safety Study of Osmotic Release Oral System (OROS) Hydromorphone in Non-Opioid Tolerant Chinese Participants With Cancer

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT01824524·12 enrolled

Buprenorphine2 trials

Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

Completed·JJohns Hopkins University·Phase 1·NCT01642030·132 enrolled

Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder

Completed·IIndivior Inc.·Phase 2·NCT02044094·39 enrolled

Liposomal Bupivacaine2 trials

Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies

Completed·MMayo Clinic·Phase 4·NCT04258631·105 enrolled

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

Recruiting·MMasonic Cancer Center, University of Minnesota·Phase 2·NCT06411795·78 enrolled

Epidural Block1 trial

Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic Colectomy

Terminated·—·N/A·NCT02164929·17 enrolled

Abuse Potential1 trial

Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users

Completed·NNational Institute on Drug Abuse (NIDA)·N/A·NCT00158236·7 enrolled

Acute Pain1 trial

Protocolized vs Discretionary Use of Opioids in Acute Pain

Completed·MMontefiore Medical Center·Phase 3·NCT00825370·350 enrolled

Abdominal pain1 trial

High Dose IV Lidocaine vs Hydromorphone for Abdominal Pain in the Emergency Department

Terminated·HHennepin Healthcare Research Institute·Phase 4·NCT04398316·4 enrolled

Effectiveness1 trial

Study to Assess Longer-term Opioid Medication Effectiveness (SALOME)

Completed·UUniversity of British Columbia·Phase 3·NCT01447212·202 enrolled

ART1 trial

Pharmacokinetic Profile of OROS Hydromorphone in Healthy Taiwanese Participants With Different Genotypes for the UGT2B7 Gene

Completed· Johnson & Johnson logo

Johnson & Johnson·Phase 1·NCT01487564·29 enrolled

Infusion1 trial

the Effect of Different Drugs and Infusion Ways on Degree of Postoperative Comfort

Completed·JJun Wang·Phase 4·NCT04111328·600 enrolled

Obese Women1 trial

TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia

Withdrawn·NNorthwestern University·Phase 4·NCT03282669

Pain Management1 trial

Acute Pain Management in Patients on Opioid Replacement Therapy

Terminated·UUniversity of California, San Francisco·Phase 1·NCT03933865·1 enrolled

Safety and Efficacy1 trial

Safety and Efficacy Study of Hydromorphone and Morphine

Completed·MMontefiore Medical Center·Phase 2·NCT00195910·198 enrolled

Nausea and vomiting1 trial

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Completed·VVanderbilt University·N/A·NCT02625181·27,034 enrolled

Severe Pain1 trial

Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain

Completed·MMontefiore Medical Center·Phase 3·NCT00627367·224 enrolled

Thoracoscopy1 trial

Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy

Completed·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 4·NCT03648008·171 enrolled

Efficacy and Safety1 trial

Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia

Unknown status·MMaternal and Child Health Hospital of Hubei Province·Phase 2·NCT06036797·240 enrolled

Musculoskeletal Injuries1 trial

Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries

Completed·UUniversity of Alberta·Phase 2·NCT03767933·710 enrolled

Nephrectomy1 trial

NSAID Use After Robotic Partial Nephrectomy

Recruiting·UUniversity of Miami·Phase 2·NCT05842044·110 enrolled

Perioperative Period1 trial

The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion

Terminated·UUniversity of Southern California·Phase 4·NCT03104816·28 enrolled

Pilot Study1 trial

Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.

Completed·—·Phase 2·NCT02437669·35 enrolled

Spinal Fusion1 trial

Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

Terminated·UUniversity of Texas Southwestern Medical Center·Phase 4·NCT03115151·46 enrolled

Orthopedic Procedures1 trial

Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?

Unknown status·MMount Sinai Hospital, Canada·N/A·NCT02880800·80 enrolled

Opioid Withdrawal1 trial

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Recruiting·UUniversity of Maryland, Baltimore·Phase 2·NCT05027919·60 enrolled

Intravenous Lidocaine1 trial

Intravenous Lidocaine Randomized Comparative Effectiveness Trial

Completed·MMontefiore Medical Center·Phase 4·NCT03300674·154 enrolled

Postpartum Depression1 trial

Effect of Tramadol in Prevention of Postpartum Depression

Completed·XXinqiao Hospital of Chongqing·Phase 4·NCT03309163·1,230 enrolled

Nausea1 trial

Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery

Completed·UUniversity Health Network, Toronto·Phase 4·NCT02295124·200 enrolled

Abdominoplasty1 trial

Study in Subjects Undergoing Complete Abdominoplasty

Completed·CConcentric Analgesics·Phase 2·NCT03789318·54 enrolled

Surgical1 trial

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

Completed·SStanford University·Phase 3·NCT02601027·120 enrolled

Analgesic1 trial

Opioid Analgesics for Acute Fracture Pain in Adults Discharged From the ED

Terminated·MMount Sinai Hospital, Canada·N/A·NCT03478423·5 enrolled

Tics1 trial

The Effects of ECMO on the Pharmacokinetics of Hydromorphone

Recruiting·XXiaobo Yang, MD·Phase 2·NCT05565495·26 enrolled

Postoperative Pain Relief1 trial

Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing Surgery

Recruiting·MMayo Clinic·Phase 4·NCT06525740·140 enrolled

Strabismus1 trial

Pain Medications in Children Undergoing Strabismus Surgery

Unknown status·—·N/A·NCT02789969·128 enrolled

Total Knee Arthroplasty1 trial

Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee Arthroplasty

Terminated·UUniversity of Southern California·Phase 4·NCT02987920·23 enrolled

Musculoskeletal Pain1 trial

Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain

Completed·JJohns Hopkins University·Phase 1·NCT02372591·14 enrolled

Postoperative Pain Management1 trial

Personalized Post-Operative Pain Management

Active, not recruiting·UUniversity of Tennessee Graduate School of Medicine·Phase 4·NCT06669650·208 enrolled

Esketamine1 trial

The Effect of Esketamine on Patients Undergoing Tumor Surgery

Unknown status·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·N/A·NCT04613869·282 enrolled

Migraine1 trial

Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute Migraine

Completed·MMontefiore Medical Center·Phase 4·NCT02389829·127 enrolled

Acetaminophen1 trial

Acetaminophen IV vs Hydromorphone IV in the ED

Completed·MMontefiore Medical Center·Phase 4·NCT03107481·220 enrolled

Hysterectomy1 trial

Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy

Completed·SState University of New York at Buffalo·Phase 3·NCT04429022·68 enrolled

Elderly Patients1 trial

Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain

Completed·MMontefiore Medical Center·Phase 2/3·NCT00305058·194 enrolled

Wound Healing1 trial

Topical Hydromorphone for Wound Healing

Terminated·HHordinsky, Maria K., MD·Phase 1/2·NCT00177060·50 enrolled

Colorectal1 trial

Intrathecal Opioids for Colorectal Resection

Completed·MMayo Clinic·Phase 4·NCT04752033·80 enrolled

Elective1 trial

Use of Intrathecal Hydromorphone in Elective Cesarean Deliveries

Completed·GGrace Shih, MD·Phase 1·NCT01866254·45 enrolled

Spinal Surgery1 trial

Methadone and Hydromorphone For Spinal Surgery

Completed·EEndeavor Health·Phase 4·NCT02107339·120 enrolled

Tramadol1 trial

The Discriminative Effects of Tramadol in Humans

Completed·NNational Institute on Drug Abuse (NIDA)·Phase 1/2·NCT00499746·20 enrolled

Respiratory Depression1 trial

Study of Respiratory Depression When Using a Hydromorphone Pain Protocol

Terminated·AAlbert Einstein Healthcare Network·N/A·NCT01784991·116 enrolled

Neuropathic Pain1 trial

Evaluating the Efficacy and Safety of Extended Release Hydromorphone (Exalgo) in Patients With Neuropathic Pain

Completed·IInternational Clinical Research Institute·Phase 4·NCT01207596·30 enrolled

Postoperative Recovery1 trial

Intraoperative Opioids and Postoperative Recovery After Hepatobiliary or Foregut Surgery

Completed·EEndeavor Health·Phase 4·NCT01546948·60 enrolled

Patient-Controlled Analgesia1 trial

Ketamine Patient-Controlled Analgesia for Acute Pain

Terminated·UUniversity of Cincinnati·Phase 3·NCT02062879·20 enrolled

Spinal Anesthesia1 trial

The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia

Completed·KKorea University Anam Hospital·N/A·NCT01172782·60 enrolled

Epidural Analgesia1 trial

A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum Repair

Terminated·—·Phase 4·NCT02056301·62 enrolled

Tonsillectomy1 trial

Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery

Completed·WWashington University School of Medicine·Phase 1·NCT04230681·189 enrolled

Hydromorphone1 trial

Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation: A Dose-exploration and Effectiveness Study

Completed·NNanfang Hospital, Southern Medical University·Approved·NCT04436224·530 enrolled

Liver Transplantation1 trial

Randomized Clinical Trial of Methadone and Ketamine for Pain Management During Deceased Donor Liver Transplant

Completed·LLahey Clinic·Approved·NCT06868589·50 enrolled

VAS Score1 trial

Hydromorphone as an Adjuvant to Ropivacaine for Adductor Canal Block in Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind, Controlled Trial

Completed·CChina-Japan Friendship Hospital·Preclinical·NCT07722234·90 enrolled

Mechanical Ventilation1 trial

Fentanyl Versus Hydromorphone as First Line Strategy in Patients on Mechanical Ventilation, a Pilot Pragmatic Randomized Superiority Clinical Trial: the FenHydro Trial

Completed·BBeth Israel Deaconess Medical Center·Phase 2·NCT07224620·319 enrolled

Fracture1 trial

Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department: a Randomized Controlled Study

Recruiting·TThe Cooper Health System·Preclinical·NCT07430345·48 enrolled

Pain1 trial

Most Effective Opioid Analgesia in Ambulatory Surgeries: a Randomized Control, Investigator Blinded, Parallel Group With Superiority Design Study of Morphine Versus Hydromorphone

Completed·MMcMaster University·Preclinical·NCT02223377·402 enrolled

Unspecified4 trials

The Effects of Hydromorphone on Responses to Verbal Tasks

Completed·UUniversity of Chicago·N/A·NCT02205983·50 enrolled

Hydromorphone Pharmacokinetic-Pharmacodynamic Fingerprint

Withdrawn·NNorthwestern University·N/A·NCT01123486

Hydromorphone and C-section

Completed·EEmory University·Phase 2·NCT01598545·20 enrolled

Show 1 more trial

Association Between Body Size and Response to Hydromorphone in ED

Completed·—·Phase 2·NCT01675778·174 enrolled

Regulatory

FDA Approval Timeline[5]

Dec 7, 1992

DILAUDID

NDA NDA019891

Sep 24, 2004

PALLADONE

NDA NDA021044

Nov 9, 2007

DILAUDID

NDA NDA019892

Mar 1, 2010

EXALGO

NDA NDA021217

Jan 16, 2020

DILAUDID

NDA NDA019034

Mar 3, 2023

HYDROMORPHONE HYDROCHLORIDE

NDA NDA200403

Dec 14, 2023

HYDROMORPHONE HYDROCHLORIDE

NDA NDA217812

Sources

References

[1]
ClinicalTrials.gov — 103 trial records for Hydromorphone. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Dilaudid drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — Hydromorphone compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for Hydromorphone. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA217812). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Dilaudid. U.S. Food & Drug Administration.
[7]
SEC EDGAR — Rhodes Pharmaceuticals, L.P. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: Mu Opioid Receptor Agonist[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: RRhodes Pharmaceuticals, L.P.

Patent Landscape[6]

Patent Cliff

Apr 23, 2032

Earliest patent expiration — generic entry possible after this date

Patent #Expires

9731082Apr 23, 2032

12653820Jan 9, 2043