GLP-2

PreclinicalSmall molecule

GGlostrup University Hospital, Copenhagen

GLP-2 is one of 19 small molecule programs targeting Short Bowel Syndrome. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Short Bowel SyndromeActive, not recruiting

Short Bowel SyndromePreclinical

Active, not recruiting

Competition

Competitive Landscape

28 competitors in Short Bowel Syndrome

#DrugCompanyPhaseTrials

Eliquis

Bristol-Myers Squibb

Approved

1 2

Byetta

AstraZeneca

Approved

1 3

Victoza

Growth Hormone

1 5

Ursodeoxycholic Acid

Daewoong Pharmaceutical Co. LTD.

Approved

1 6

Dipeptidyl Peptidase 4 Inhibitor

Boehringer Ingelheim

Approved

1 7

Questran

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 2

1 8

Rhgh

XXiamen Amoytop Biotech Co., Ltd.

Phase 3

1 9

Teduglutide /kg

Takeda

Phase 3

3 10

Apraglutide

VVectivBio AG

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2027

N/ARecruiting

Function

NCT06194955

Clinical

Trials by Indication[1]

Function1 trial

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function

Recruiting·UUniversity of Copenhagen·N/A·NCT06194955·60 enrolled

Short Bowel Syndrome1 trial

Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Short Bowel Syndrome

Unknown status·GGlostrup University Hospital, Copenhagen·N/A·NCT00673751·8 enrolled

Lip1 trial

Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon Like Peptide 2

Completed·UUniversity Health Network, Toronto·Phase 3·NCT01958775·12 enrolled

Acute Lymphoblastic Leukemia1 trial

Effect of Glucagon-like Peptide 2 on Gallbladder Motility After a Meal in Young, Healthy Male Subjects

Completed·SSteno Diabetes Center Copenhagen·Phase 1·NCT03682172·15 enrolled

Humans1 trial

The Importance of Glucagon-Like Peptide-2 (GLP-2)in Mesenteric Bloodflow in Humans

Unknown status·GGlostrup University Hospital, Copenhagen·N/A·NCT00273000·10 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for GLP-2. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — GLP-2 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for GLP-2. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Glostrup University Hospital, Copenhagen company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: GGlostrup University Hospital, Copenhagen

GLP-2

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2027

Trials by Indication[1]

Function1 trial

Short Bowel Syndrome1 trial

Lip1 trial

Acute Lymphoblastic Leukemia1 trial

Humans1 trial

References

Drug Info

Quick Facts

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