Genotropin

(Somatropin)

ApprovedSmall molecule

Somatropin is a synthetic human growth hormone used to treat growth hormone deficiency in children and adults, helping them grow taller and develop normally. It's also used to treat certain conditions like Turner syndrome and muscle-wasting diseases.[2] Genotropin is currently approved and in use across 20 indications[4].[1]

Genotropin is one of 272 small molecule programs targeting Growth Hormone Deficiency. It is currently in Approved.

Indications

123

Total Trials

Active Trials

271

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Pipeline

Status by Indication[4][1]

Indication

Growth Hormone DeficiencyTerminated

HIV InfectionUnknown

Osteoporosis-Pseudoglioma SyndromeActive, not recruiting

Werner SyndromeActive, not recruiting

Insulin ResistanceActive, not recruiting

Chronic Renal Failure SyndromeActive, not recruiting

Polycystic Ovary SyndromeActive, not recruiting

Pituitary DwarfismUnknown

Pituitary Gland DiseaseUnknown

CachexiaUnknown

Growth Hormone DeficiencyApproved

Terminated

HIV InfectionPreclinical

Unknown

Osteoporosis-Pseudoglioma SyndromePreclinical

Active, not recruiting

Werner SyndromePreclinical

Active, not recruiting

Insulin ResistancePreclinical

Active, not recruiting

Chronic Renal Failure SyndromePreclinical

Active, not recruiting

Polycystic Ovary SyndromePreclinical

Active, not recruiting

Pituitary DwarfismPreclinical

Unknown

Pituitary Gland DiseasePreclinical

Unknown

CachexiaPreclinical

Unknown

Showing 10 of 20 indications

Competition

Competitive Landscape

123 competitors in HIV Infection

#DrugCompanyPhaseTrials

Genotropin

Arava

Reyataz

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Approved

4 4

Zometa

Lotrimin

Incivek

Vertex Pharmaceuticals

Viread

Zofran

Hepsera

Golytely

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2027

Phase 2Active, not recruiting

Turner Syndrome

NCT05690386

Q3 2028

Phase 2Active, not recruiting

Growth

NCT05382637

Q1 2029

PreclinicalActive, not recruiting

Knee Osteoarthritis (knee OA)

NCT07036003

Q3 2029

Phase 3Recruiting

Adult Growth Hormone Deficiency

NCT04867317

Clinical

Trials by Indication[1]

Growth35 trials

An Observational Study (Registry) Assessing Treatment Outcomes and Safety for Children and Adults Who Are Prescribed Norditropin® (Human Growth Hormone)

Completed· Novo Nordisk logo

Novo Nordisk··NCT01009905·22,960 enrolled

Prevention of Growth Retardation by Early Treatment With Growth Hormone (GH) in Children With CJA Treated by Corticosteroid Therapy

Terminated· Pfizer logo

Pfizer·Phase 3·NCT00174291·21 enrolled

Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Completed·OOPKO Health, Inc.·Phase 2·NCT01592500·56 enrolled

Show 32 more trials

Three Times Weekly (TIW) Growth Hormone Therapy in Children on Hemodialysis

Completed·NNationwide Children's Hospital·Phase 3·NCT00943995·3 enrolled

Randomized Clinical Trial of Two Different Initial Growth Hormone Doses in Children

Unknown status·NNorthwell Health·Phase 3·NCT06103513·50 enrolled

Substrate Metabolism, Growth Hormone Signaling (GH), and Insulin Sensitivity During GH and Ketone Bodies Infusion

Completed·UUniversity of Aarhus·N/A·NCT02655263·10 enrolled

Effect of Somatropin on Left Ventricular Mass in Growth Hormone Deficient Adult Patients

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT01562834·22 enrolled

Growth Hormone (GH) in in Vitro Fertilization (IVF) Poor-responder Patients

Terminated·FFundacion Dexeus·Phase 2·NCT01298960·52 enrolled

Effects of Growth Hormone on the Nitric Oxide Pathway

Completed·HHannover Medical School·Phase 1·NCT00470002·16 enrolled

Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Completed·OOPKO Health, Inc.·Phase 3·NCT02968004·224 enrolled

National Cooperative Growth Study (NCGS): A Post-marketing Surveillance Program for Nutropin, Nutropin AQ, Nutropin Depot, and Protropin

Completed· Roche logo

Roche··NCT00097539·65,205 enrolled

Growth Hormone Treatment of Children With HIV-Associated Growth Failure

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00006143·102 enrolled

Low and Conventional Dose of Somatropin in Growth Hormone Deficient Adult Patients

Completed· Eli Lilly logo

Eli Lilly·Phase 3·NCT00570011·112 enrolled

Evolution Of Growth Rate In Children With Growth Retardation Due to Glucocorticosteroid Therapy And Treated By Genotonorm

Completed· Pfizer logo

Pfizer·Phase 3·NCT00163189·98 enrolled

MAXOMAT ® in the Treatment of Severe Early Onset Intrauterine Growth Retardation on Pre-pubertal Children

Completed· Sanofi logo

Sanofi·Phase 3·NCT00452491·306 enrolled

Administration of Growth Hormone to Increase CD4+ Count in Patients Taking Anti-HIV Drugs

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00050921·60 enrolled

A 4 Year Combination Therapy of Growth Hormone and (GnRH) Agonist in Children With a Short Predicted Height

Unknown status·BBelgian Study Group for Pediatric Endocrinology·Phase 4·NCT00840944·44 enrolled

Long Term Effect of Somatropin in Subjects With Intrauterine Growth Retardation

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT01734447·57 enrolled

Growth Retardation In Children With Special Pathological Conditions Or Disease

Completed· Pfizer logo

Pfizer·Phase 3·NCT00163215·46 enrolled

A Prospective Observational Study of Effect of Somatropin on Growth Hormone Deficient Adults

Completed· Eli Lilly logo

Eli Lilly··NCT01088399·10,673 enrolled

Growth Response in Short Children Suffering From a Disease With Growth Retardation and Treated With Somatropin

Completed·UUniversity of Erlangen-Nürnberg Medical School·Phase 2·NCT00488124·120 enrolled

Clinical Trial of Growth Hormone in MPS I, II, and VI

Terminated·LLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center·Phase 2/3·NCT00748969·2 enrolled

Growth Hormone to Increase Immune Function in People With HIV

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00071240·22 enrolled

Growth Hormone Therapy for Muscle Regeneration in Severely Burned Patients

Completed·TThe University of Texas Medical Branch, Galveston·Phase 2/3·NCT03038594·13 enrolled

Somatropin (Norditropin) in Insulin-like Growth Factor (IGF) Deficient Children

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00102817·149 enrolled

Growth Hormone Treatment of Children Born With Retarded Intrauterine Growth at Age 2-5 Years

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00184691·78 enrolled

Growth Hormone Treatment of Children Diagnosed of Intrauterine Growth Retardation

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT01697644·75 enrolled

Efficacy on Height in SGA Children Treated With Growth Hormone

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00184756·151 enrolled

A Study to Evaluate Growth in Participants Treated With Somatropin (Nutropin) Using NuSpin Device

Terminated· Roche logo

Roche··NCT01243892·18 enrolled

A Single Dose Trial in Growth Hormone Deficient Children Investigating Safety, Pharmacokinetics and Pharmacodynamics of Long Acting Growth Hormone

Completed· Novo Nordisk logo

Novo Nordisk·Phase 2·NCT00936403·31 enrolled

A Phase 2, Safety and Dose-Finding Study in Treatment-Naive, Pre-Pubertal, Growth Hormone-Deficient Children

Terminated· Teva logo

Teva·Phase 2·NCT02092077·65 enrolled

Growth Hormone in a Patient With a Dominant-Negative GHR Mutation

Active, not recruiting·—·Phase 2·NCT05382637·1 enrolled

Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy

Completed·TThe University of Texas Medical Branch, Galveston·Phase 3·NCT03554265·72 enrolled

Growth Hormone Administration and Its Effects on Cardiovascular Risk Factors in Growth Hormone Deficient Women

Completed·MMassachusetts General Hospital·N/A·NCT00136032·63 enrolled

The Relationship Between the Growth Hormone (GH)- Insulin Like Growth Factor I (IGF-I) System and the Inflammatory System in Healthy Normal Persons

Unknown status·HHerlev Hospital·N/A·NCT00969644·12 enrolled

Growth Hormone Deficiency24 trials

Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00184678·161 enrolled

French National Registry of Adults With Growth Hormone Deficiency Treated With Somatropin

Completed· Novo Nordisk logo

Novo Nordisk··NCT01580605·331 enrolled

Safety and Efficacy of Somatropin in Children With Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT01502124·78 enrolled

Show 21 more trials

Evaluating Acceptance of New Liquid Somatropin Formulation in Children With Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT01563926·168 enrolled

Extension Study on Safety of Long-Term Growth Hormone Replacement in Adult Patients With Growth Hormone Deficiency

Completed· Eli Lilly logo

Eli Lilly·Phase 3·NCT00191360·68 enrolled

Evaluation of Efficacy and Safety of Recombinant Somatroipn in Patients With Growth Hormone Deficiency

Completed· Daewoong Pharmaceutical Co. LTD. logo

Daewoong Pharmaceutical Co. LTD.·Phase 3·NCT02693522·52 enrolled

Growth Hormone Deficiency in Adults (GHDA)

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00519558·121 enrolled

Efficacy and Safety of a High Dosage Compared to the Label Dosage of Somatropin in Early Pubertal Stage Children With Growth Hormone Deficiency

Completed· Eli Lilly logo

Eli Lilly·Phase 3·NCT00191165·27 enrolled

A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT02382939·92 enrolled

Comparison of Two Growth Hormone Dosing Methods in Adults With Growth Hormone Deficiency

Completed· Eli Lilly logo

Eli Lilly·Phase 4·NCT00490191·387 enrolled

Study of Weekly ALTU-238 Compared With Daily Nutropin AQ in Prepubertal Children With Growth Hormone Deficiency

Unknown status·AAltus Pharmaceuticals·Phase 2·NCT00837863·36 enrolled

Efficacy of Somatropin in Adult Patients With Isolated Growth Hormone Deficiency

Terminated· Pfizer logo

Pfizer·Phase 3·NCT00630487·9 enrolled

Liquid Somatropin Formulation in Children With Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT00567385·176 enrolled

A Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) Injection (Nutropin AQ®) in Children With Growth Hormone Deficiency

Completed· Roche logo

Roche·Phase 4·NCT02311894·82 enrolled

Observational Study of the Safety and Efficacy of Norditropin® in Adult Patients With Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk··NCT01109017·387 enrolled

Long-term Trial on Growth Hormone Deficiency in Adults (GHDA)

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00184730·86 enrolled

Effect of Growth Hormone in Children With Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00262249·173 enrolled

Non-interventional Study of Patients Using Norditropin® for Growth Hormone Deficiency or Turner Syndrome

Completed· Novo Nordisk logo

Novo Nordisk··NCT01604161·2,016 enrolled

Surveillance of Treatment of Children With Growth Hormone Deficiency With Zomacton®

Withdrawn· Ferring logo

Ferring··NCT01731028

Long-term Trial on Growth Hormone Deficiency in Adults (GHDA)

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00184743·112 enrolled

A Trial Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Dose of Long-acting Growth Hormone (Somapacitan) Compared to Daily Dosing of Norditropin® SimpleXx® in Children With Growth Hormone Deficiency

Completed· Novo Nordisk logo

Novo Nordisk·Phase 1·NCT01973244·32 enrolled

Trial to Compare the Efficacy and Safety of NNC0195-0092 (Somapacitan) With Placebo and Norditropin® FlexPro® (Somatropin) in Adults With Growth Hormone Deficiency.

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT02229851·301 enrolled

Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone Deficiency

Terminated· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT01698944·7 enrolled

foresiGHt: A Multicenter, Randomized, Parallel-arm, Placebo-controlled (Double- Blind) and Active-controlled (Open-label) Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency

Completed·AAscendis Pharma Endocrinology Division A/S·Phase 3·NCT04615273·264 enrolled

Small for gestational age10 trials

Long Term Metabolic Safety of Norditropin® Treatment of Small for Gestational Age (SGA) Subjects

Completed· Novo Nordisk logo

Novo Nordisk··NCT00787878·153 enrolled

Growth Hormone Treatment in Short Children Born Small for Gestational Age

Completed· Eli Lilly logo

Eli Lilly·Phase 3·NCT00191529·200 enrolled

Observational Study of the Safety and Efficacy of Norditropin® in Patients With SGA (Small for Gestational Age) Short Stature That Are Still Growing

Completed· Novo Nordisk logo

Novo Nordisk··NCT01110928·227 enrolled

Show 7 more trials

Growth Hormone Treatment in Children Born Small for Gestational Age: Assessment of Satisfaction

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT00519844·5 enrolled

Long Term Use of Somatropin in Patients Small for Gestational Age

Completed· Pfizer logo

Pfizer··NCT00793325·920 enrolled

Special Investigation Of Genotropin Long Follow-Up For Patients With A Small For Gestational Age "Scoped for Japanese"

Completed· Pfizer logo

Pfizer··NCT01897766·482 enrolled

Growth Hormone Treatment in Children Born Small for Gestational Age (SGA)

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00184717·98 enrolled

Efficacy and Safety of Growth Hormone Treatment in Children Small for Gestational Age

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00557336·160 enrolled

Neuromuscular Changes In Small For Gestational Age Children During Somatropin Therapy

Terminated· Pfizer logo

Pfizer·Phase 3·NCT00625872·23 enrolled

French National Registry of Children Born Small for Gestational Age Treated With Somatropin

Completed· Novo Nordisk logo

Novo Nordisk··NCT01578135·291 enrolled

Turner syndrome6 trials

Somatropin Treatment to Final Height in Turner Syndrome

Completed· Eli Lilly logo

Eli Lilly·Phase 3·NCT00191113·154 enrolled

Safety of Somatropin and Induction of Puberty With 17-beta-oestradiol in Girls With Turner Syndrome

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT01518062·65 enrolled

A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome

Active, not recruiting·AAscendis Pharma Endocrinology Division A/S·Phase 2·NCT05690386·48 enrolled

Show 3 more trials

Growth Response in Girls With Turner Syndrome

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT01734486·31 enrolled

The Effect of Growth Hormone in Very Young Girls With Turner Syndrome

Completed· Eli Lilly logo

Eli Lilly·Phase 3·NCT00406926·100 enrolled

Use of Somatropin in Turner Syndrome

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT01518036·57 enrolled

Short stature4 trials

Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short Stature

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT01778023·54 enrolled

Treatment With Recombinant Human Growth Hormone Genotonorm (Registered) In Children With Short Stature Secondary

Completed· Pfizer logo

Pfizer·Phase 3·NCT00174278·14 enrolled

Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy

Terminated· Pfizer logo

Pfizer·Phase 3·NCT00174187·30 enrolled

Show 1 more trial

Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short Stature

Completed· Eli Lilly logo

Eli Lilly·Phase 3·NCT00355030·91 enrolled

30 more indications

Adult3 trials

Bioequivalence of Two Products (Norditropin® Versus Nutropin AQ®) in Healthy Adult Volunteers

Withdrawn· Novo Nordisk logo

Novo Nordisk·Phase 1·NCT01512095

Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult Volunteers

Completed· Novo Nordisk logo

Novo Nordisk·Phase 1·NCT01401244·30 enrolled

Drug Use Investigation of Somatropin for GHD-ADULTS.

Completed· Pfizer logo

Pfizer··NCT00601419·230 enrolled

Noonan syndrome3 trials

Somatropin Effect on Linear Growth and Final Height in Subjects With Noonan Syndrome

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT01529840·24 enrolled

Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan Syndrome

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT01927861·51 enrolled

Post Marketing Surveillance on Long-term Use With Norditropin® (Short Stature Due to Noonan Syndrome)

Completed· Novo Nordisk logo

Novo Nordisk··NCT03435627·71 enrolled

Safety and Efficacy3 trials

Safety and Efficacy of Long-term Somatropin Treatment in Adults

Completed· Novo Nordisk logo

Novo Nordisk··NCT01543880·752 enrolled

Safety and Efficacy of Long-term Somatropin Treatment in Children

Completed· Novo Nordisk logo

Novo Nordisk··NCT01543867·5,442 enrolled

A Non-inferiority Phase 2 Study to Evaluate the Safety and Efficacy of PEG-rhGH in the Treatment of AGHD

Unknown status· Changchun GeneScience Pharmaceutical Co., Ltd. logo

Changchun GeneScience Pharmaceutical Co., Ltd.·Phase 2·NCT03104010·180 enrolled

Treatment2 trials

The Effect of Somatropin Treatment in Adult Patients on Chronic Dialysis

Terminated· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT00503698·712 enrolled

Evaluation of Overall Compliance and Duration of Zomacton® Treatment With the Zomajet® Needle-free Device

Completed· Ferring logo

Ferring··NCT01306357·87 enrolled

Observational Study2 trials

An Observational Study Validating a Score That Quantifies the Therapeutic Response to Treatment With Norditropin®

Completed· Novo Nordisk logo

Novo Nordisk··NCT00934063·121 enrolled

Observational Study of Somatropin Treatment in Children

Completed· Eli Lilly logo

Eli Lilly··NCT01088412·22,845 enrolled

Insulin resistance2 trials

Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature

Terminated·MMassachusetts General Hospital··NCT00121875·1 enrolled

Study to Examine Insulin Resistance During Growth Hormone Treatment for Short Stature Due to Low Birthweight

Unknown status·MMassachusetts General Hospital··NCT00120497·12 enrolled

Children2 trials

Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq

Completed· Ipsen logo

Ipsen·Phase 3·NCT00234533·251 enrolled

Somatropin Therapy In Children Born Preterm But Appropriate For Gestational Age

Completed· Pfizer logo

Pfizer·Phase 2·NCT00174460·33 enrolled

Testosterone1 trial

Study of Testosterone and rHGH in FSHD

Completed·UUniversity of Rochester·Phase 1·NCT03123913·20 enrolled

End-Stage Renal Disease1 trial

Pharmacokinetics of Somatropin in Patients With End Stage Renal Disease Receiving Chronic Haemodialysis

Completed· Novo Nordisk logo

Novo Nordisk·Phase 1·NCT01502137·21 enrolled

Atrophy1 trial

Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears

Completed·UUniversity of Michigan·Phase 2·NCT02420353·20 enrolled

X-linked hypophosphatemic rickets1 trial

Effects of GH on Body Proportions and Final Height in X-Linked Hypophosphatemic Rickets

Unknown status·UUniversity of Rostock·Phase 1·NCT00473187

Heart Failure1 trial

Growth Hormone in Ischemic Heart Failure

Completed·GGöteborg University·Phase 3·NCT04420481·37 enrolled

Renal insufficiency1 trial

Growth Hormone Treatment in Infants Aged 1 to 2 Years With Chronic Renal Insufficiency (CRI) and Growth Retardation.

Completed· Novo Nordisk logo

Novo Nordisk·Phase 4·NCT00184769·16 enrolled

Single Dose1 trial

A Single Dose Trial in Healthy Caucasians and Japanese Subjects Investigating the Pharmacokinetics of Somatropin

Completed· Novo Nordisk logo

Novo Nordisk·Phase 1·NCT00931476·86 enrolled

Prader-Willi syndrome1 trial

Retrospective Observational Study on Efficacy and Safety of Norditropin® in Children With Prader-Willi Syndrome

Completed· Novo Nordisk logo

Novo Nordisk··NCT00705172·41 enrolled

CLE1 trial

Skeletal Muscle Effects of GH in Boys

Completed·NNemours Children's Clinic··NCT04020913·45 enrolled

Ovarian1 trial

The Effect of Myo-inositol, Somatropin, and DHEA on Poor Ovarian Responders

Unknown status·—·Phase 2/3·NCT05900661·300 enrolled

Alcoholic Fatty Liver Disease1 trial

Augmenting Growth Hormone to Ameliorate Nonalcoholic Fatty Liver Disease in Adolescents

Completed·MMassachusetts General Hospital·Phase 1·NCT02726542·24 enrolled

Tics1 trial

Safety, Pharmacokinetics and Pharmacodynamics Study of HL-032 in Healthy Male Volunteers

Completed·HHanAll BioPharma Co., Ltd.·Phase 1·NCT01440686·40 enrolled

Tibia Fracture1 trial

Controlled Study to Evaluate the Efficacy and Safety of the Treatment With Growth Hormone in Tibia Fractures

Completed· Novo Nordisk logo

Novo Nordisk·Phase 2·NCT00254514·407 enrolled

Chronic Kidney Disease1 trial

Growth Hormone Treatment in Adult Patients With Chronic Kidney Disease

Completed· Novo Nordisk logo

Novo Nordisk·Phase 2·NCT00184652·140 enrolled

Prospective1 trial

Observational Prospective Study on Patients Treated With Norditropin®

Completed· Novo Nordisk logo

Novo Nordisk··NCT00960128·21,249 enrolled

Acceptability1 trial

Evaluation of the Adherence and the Patient Acceptability of Zomacton® Treatment With the Zomajet® Vision X Device

Terminated· Ferring logo

Ferring··NCT02018172·3 enrolled

Trial1 trial

Genetic Testing of Noonan Subjects Previously Treated With Norditropin®. An Extension to Trial GHNOO-1658

Completed· Novo Nordisk logo

Novo Nordisk·Phase 3·NCT01529944·22 enrolled

Labor1 trial

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.

Unknown status·AAzidus Brasil·Phase 1·NCT01494779·32 enrolled

Achondroplasia1 trial

A Survey Collecting Data on Adult Height in Patients With Achondroplasia Treated With Somatropin

Completed· Novo Nordisk logo

Novo Nordisk··NCT01435629·81 enrolled

Tendinopathy1 trial

A Study to Evaluate the Efficacy of Somatropin in the Treatment of Patellar Tendinopathy

Withdrawn·HHospital for Special Surgery, New York·Phase 2·NCT02597660

Knee Osteoarthritis (Knee OA)1 trial

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR): a Pilot, Randomized Placebo-controlled Trial

Active, not recruiting·DDr. David Wasserstein·Preclinical·NCT07036003·34 enrolled

Adult Growth Hormone Deficiency1 trial

CSP #2018 - Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

Recruiting·VVA Office of Research and Development·Phase 3·NCT04867317·172 enrolled

Unspecified5 trials

6x3 Crossover, Bioavailability, Safety and Tolerability Among Different Eutropin Formulations in Healthy Volunteers

Completed·LLG Chem·Phase 1·NCT04085224·24 enrolled

rHGH and Intestinal Permeability in Intestinal Failure

Completed·NNorthwestern University·Phase 4·NCT01380366·15 enrolled

Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.

Completed·LLG Life Sciences·Phase 4·NCT03015909·116 enrolled

Show 2 more trials

Special Survey for Long Term Application

Completed· Novo Nordisk logo

Novo Nordisk··NCT01516229·395 enrolled

Generation of Biological Samples Positive to Somatropin for Anti-doping Control

Completed·PParc de Salut Mar·Phase 1·NCT04042428·6 enrolled

Regulatory

FDA Approval Timeline[5]

Oct 16, 1986

HUMATROPE

BLA BLA019640

May 25, 1995

ZOMACTON

BLA BLA019774

Aug 24, 1995

GENOTROPIN

BLA BLA020280

Aug 24, 1995