Hepatitis A vaccine

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

COVID-19InfluenzaHepatitisJapanese EncephalitisTyphoid FeverChickenpox

1931 competitors in COVID-19

#DrugCompanyPhaseTrials

1

Hepatitis A vaccine

Sanofi

Approved

22

Spikevax

Moderna

Preclinical

213

Bnt162b2

BioNTech

Preclinical

294

SARS-COV-2 VACCINE

Moderna

Preclinical

25

Glucocorticoid

AbbVie

Preclinical

16

Statins

Sanofi

Preclinical

17

HB-Admscs

HHope Biosciences Research Foundation

Preclinical

48

Interferon-Gamma

SSPP Pharmaclon Ltd.

Preclinical

19

MRNA COVID-19 Vaccine

Novartis

Preclinical

410

Exoflo

DDirect Biologics, LLC

Preclinical

3Show 10 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Hepatitis10 trials

Immunogenicity Study of an Inactivated Hepatitis A Vaccine in Infants and Young Children

Completed·CCenters for Disease Control and Prevention·Phase 4·NCT00139113·248 enrolled

Safety and Immunogenicity of Measles Vaccine, Varicella Vaccine and Hepatitis-A Vaccine

Unknown status·UUniversity of Witwatersrand, South Africa·Phase 4·NCT03330171·278 enrolled

A Study to Compare the Efficacy of Hepatitis A Vaccine and Immune Globulin When Given After Exposure to Hepatitis A

Completed·CCenters for Disease Control and Prevention·N/A·NCT00139139·1,500 enrolled

Show 7 more trials

Effectiveness of Hepatitis A Virus Vaccination Among Homosexual Males at Risk for Hepatitis A Infection

Completed·NNational Taiwan University Hospital·N/A·NCT01102296·582 enrolled

PCV13 + Hepatitis a Vaccine for Adults

Completed·HHelsinki University Central Hospital·Phase 4·NCT01926860·305 enrolled

Comparative Immunogenicity Study of Two Hepatitis A Vaccines

Unknown status·CChina National Biotec Group Company Limited·Phase 4·NCT03231605·300 enrolled

Serological Evaluation of Varicella and Hepatitis A Vaccines Using Injector Delivery

Unknown status·UUniversity of Sao Paulo General Hospital·Phase 2/3·NCT00926419·600 enrolled

Hepatitis A Vaccine in Patients With Immunomodulating Drugs

Completed·LLars Rombo·Phase 2·NCT01360970·68 enrolled

Persistence of Hepatitis A Antibody in Healthy Adults ~32 Years Post Vaccination.

Unknown status·BBest Healthcare Inc.·Phase 4·NCT06184230·300 enrolled

Three Doses of Hepatitis A Vaccine in Patients With Immunomodulating Drugs

Unknown status·SSormland County Council, Sweden·Phase 2·NCT01446978·150 enrolled

Chickenpox5 trials

A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age

Recruiting·GSK·Phase 3·NCT06693895·750 enrolled

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

Recruiting·GSK·Phase 3·NCT06740630·1,840 enrolled

A Study on the Immune Response and Safety of Various Potencies of an Investigational Chickenpox Vaccine Compared With a Marketed Chickenpox Vaccine, Given to Healthy Children 12 to 15 Months of Age

Completed·GSK·Phase 2·NCT05084508·800 enrolled

Show 2 more trials

A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age

Recruiting·GSK·Phase 3·NCT06806137·600 enrolled

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age

Recruiting·GSK·Phase 3·NCT06855160·900 enrolled

Immunogenicity4 trials

Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent VLP Vaccine

Completed·Takeda·Phase 2·NCT02038907·420 enrolled

A Controlled Study to Evaluate the Safety and Immunogenicity of StreptAnova™ in Healthy Adults

Unknown status·—·Phase 1·NCT02564237·39 enrolled

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

Completed·Sanofi·Phase 3·NCT03537508·2,627 enrolled

Show 1 more trial

Immunogenicity and Safety of Sanofi Pasteur's AVAXIM 80U Pediatric Vaccine Followed by Booster Dose

Completed·Sanofi·Phase 3·NCT00483470·720 enrolled

Immune System4 trials

Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors

Completed·WWake Forest University Health Sciences··NCT02747407·55 enrolled

Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy

Terminated·NNational Cancer Institute (NCI)·Phase 2·NCT01339000·1 enrolled

The Effects of Anti-HIV Therapy on the Immune Systems of Children and Young Adults Infected With HIV

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00004735·81 enrolled

Show 1 more trial

A Study to Test If Giving Remune (an HIV Vaccine) Can Improve the Immune Systems of HIV-Positive Patients Who Are Also Participating in ACTG 328

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000943·50 enrolled

Pediatric2 trials

Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants

Completed·Sanofi·Phase 2·NCT04398706·852 enrolled

Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa

Completed·Sanofi·Phase 3·NCT05794230·1,528 enrolled

14 more indications

COVID-192 trials

The COVID-19 VaccinE Response and Co-Administration in Rheumatology Patients (COVER-CoAd)

Active, not recruiting·OOregon Health and Science University·Phase 4·NCT05543642·129 enrolled

A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19

Completed·CCureVac·Phase 2·NCT04515147·668 enrolled

Japanese encephalitis1 trial

Study of ChimeriVax™-Japanese Encephalitis Vaccine in Toddlers in Thailand and the Philippines

Completed·Sanofi·Phase 3·NCT00735644·1,200 enrolled

Immune Response1 trial

Evaluation of the Safety and Immune Responses of the Towne Strain of CMV in Seronegative Women

Terminated·VVirginia Commonwealth University·Phase 2/3·NCT00201448·82 enrolled

Influenza1 trial

Hutterite Influenza Prevention Study

Completed·MMcMaster University·Phase 4·NCT00877396·4,771 enrolled

Yellow Fever1 trial

Study of Yellow Fever Vaccine Administered With Tetravalent Dengue Vaccine in Healthy Toddlers

Completed·Sanofi·Phase 3·NCT01436396·792 enrolled

Phase 11 trial

Phase 1 Study of MGD010 in Healthy Subjects

Completed·MMacroGenics·Phase 1·NCT02376036·73 enrolled

HPV Vaccination1 trial

Transmission Reduction and Prevention With HPV Vaccination (TRAP-HPV) Study

Completed·MMcGill University·Phase 4·NCT01824537·372 enrolled

Vaccine1 trial

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

Recruiting·Sanofi·Phase 3·NCT07348692·896 enrolled

Infections1 trial

A Study on the Rate of Opportunistic (AIDS-Related) Infections Among HIV-Positive Children Who Have Stopped Taking Their OI Preventive Medications

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00001078·200 enrolled

Immune1 trial

Increasing HAART-Induced Immune Restoration With Cyclosporine

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00031070·40 enrolled

Randomized1 trial

A Phase I Randomized, Observer-Blinded, Dose-Ranging Study in Healthy Subjects 24 to <72 Months of Age

Completed·NNovavax·Phase 1·NCT02296463·32 enrolled

Effectiveness1 trial

A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000896·24 enrolled

Vaccination1 trial

Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood

Completed·IInternational Vaccine Institute·Phase 4·NCT00125047·27,231 enrolled

Typhoid Fever1 trial

Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever

Completed·IInternational Vaccine Institute·Phase 4·NCT00125008·37,673 enrolled

Details

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