Human Coagulation Factor VIII

Phase 3Small molecule

Roche

Human Coagulation Factor VIII is one of 21 small molecule programs targeting Hemophilia A. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Hemophilia aRecruiting

Hemophilia aPhase 3

Recruiting

Competition

Competitive Landscape

35 competitors in Hemophilia a

#DrugCompanyPhaseTrials

Hemlibra

Roche

Approved

16 2

Rayos

RRoxane Laboratories

Approved

1 3

Cyklokapron

Efanesoctocog Alfa

7 5

Advate

Takeda

Phase 3

4 6

Marstacimab

Pfizer

Phase 3

1 7

Qfitlia

GGenzyme, a Sanofi Company

Phase 3

1 8

Rfviia

Roche

Phase 3

2 9

PF-06741086

Pfizer

Phase 3

2 10

SCT800

SSinocelltech Ltd.

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2031

Phase 3Recruiting

Hemophilia a

NCT07416526

Clinical

Trials by Indication[1]

Hemophilia A1 trial

A Multicenter, Randomized, Open-Label, Phase III Clinical Trial to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of NXT007 Prophylaxis Versus Factor VIII Prophylaxis in People With Hemophilia A Without Inhibitors

Recruiting· Roche logo

Roche·Phase 3·NCT07416526·126 enrolled

Sources

References

[1]
ClinicalTrials.gov — 1 trial record for Human Coagulation Factor VIII. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Human Coagulation Factor VIII compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Human Coagulation Factor VIII. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Roche company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: Roche

Human Coagulation Factor VIII

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2031

Trials by Indication[1]

Hemophilia A1 trial

References

Drug Info

Quick Facts

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