Corvert

(Ibutilide)

PreclinicalSmall molecule

Pfizer

Corvert is one of 37 small molecule programs targeting Atrial Fibrillation. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

FDA Application

NDA/BLA/ANDA regulatory filings

Pipeline

Status by Indication[3][1]

Indication

Atrial FibrillationActive, not recruiting

GANTerminated

Atrial FibrillationPreclinical

Active, not recruiting

GANPreclinical

Terminated

Competition

Competitive Landscape

137 competitors in Atrial Fibrillation

#DrugCompanyPhaseTrials

Calquence

AstraZeneca

Preclinical

1 2

Rituxan

Coumadin

3 4

Brukinsa

BBeOne Medicines

Preclinical

1 5

Imbruvica

PPharmacyclics LLC.

Preclinical

1 6

Versed

CConrado Roberto Hoffmann Filho

Preclinical

1 7

Ondexxya

UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology

Preclinical

1 8

Romazicon

CConrado Roberto Hoffmann Filho

Preclinical

1 9

Statin

Bristol-Myers Squibb

Preclinical

1 10

Low-Molecular-Weight Heparin

Daiichi Sankyo

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Drug1 trial

Novel Approaches for Minimizing Drug-Induced QT Interval Lengthening

Completed·IIndiana University·Phase 4·NCT04675788·73 enrolled

Torsades de Pointes1 trial

Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes

Completed·IIndiana University·Phase 4·NCT02513940·14 enrolled

Progesterone1 trial

Influence of Progesterone Administration on Drug-Induced QT Interval Lengthening

Completed·IIndiana University·Phase 2·NCT01929083·19 enrolled

Women1 trial

Reducing the Risk of Drug-Induced QT Interval Lengthening in Women

Completed·IIndiana University·Phase 4·NCT03834883·27 enrolled

Atrial Fibrillation1 trial

Modified Ablation Guided by Ibutilide Use in Chronic Atrial Fibrillation

Completed·VVivek Reddy·N/A·NCT01014741·200 enrolled

1 more indication

GAN1 trial

ECGi Ibutilide: Effect of Ibutilide on AF Source Location and Organization

Terminated·VVivek Reddy·N/A·NCT03370536·1 enrolled

Regulatory

FDA Approval Timeline[4]

Dec 28, 1995

CORVERT

NDA NDA020491

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Ibutilide. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Ibutilide compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Ibutilide. EMBL-EBI & Wellcome Sanger Institute.
[4]
OpenFDA — FDA approval records (NDA NDA020491). U.S. Food & Drug Administration.
[5]
SEC EDGAR — Pfizer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: Pfizer

Corvert

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Drug1 trial

Torsades de Pointes1 trial

Progesterone1 trial

Women1 trial

Atrial Fibrillation1 trial

GAN1 trial

FDA Approval Timeline[4]

References

Drug Info

Quick Facts

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