Statin

Phase 3Small molecule

Bristol-Myers Squibb

Statin is one of 369 small molecule programs targeting Acute Pancreatitis. It is currently in Phase 3.

Indications

Total Trials

Active Trials

368

Competitors

Pipeline

Status by Indication[3][1]

Indication

Acute PancreatitisActive, not recruiting

Hepatocellular CarcinomaActive, not recruiting

Atrial FibrillationActive, not recruiting

COVID-19Active, not recruiting

Metabolic SyndromeActive, not recruiting

Cardiovascular DiseaseActive, not recruiting

Coronary Artery BypassActive, not recruiting

Prostate CancerActive, not recruiting

Heart DiseaseActive, not recruiting

Heart FailureActive, not recruiting

Acute PancreatitisPreclinical

Active, not recruiting

Hepatocellular CarcinomaPreclinical

Active, not recruiting

Atrial FibrillationPreclinical

Active, not recruiting

COVID-19Preclinical

Active, not recruiting

Metabolic SyndromePreclinical

Active, not recruiting

Cardiovascular DiseasePreclinical

Active, not recruiting

Coronary Artery BypassPreclinical

Active, not recruiting

Prostate CancerPreclinical

Active, not recruiting

Heart DiseasePreclinical

Active, not recruiting

Heart FailurePreclinical

Active, not recruiting

Showing 10 of 13 indications

Competition

Competitive Landscape

348 competitors in Prostate Cancer

#DrugCompanyPhaseTrials

Keytruda

Merck & Co.

Phase 3

26 2

Tecentriq

Roche

Phase 3

8 3

Alinamin

Roche

Phase 3

6 4

Verzenio

Eli Lilly

Phase 3

5 5

Orgovyx

Sumitomo Pharma America, Inc.

Phase 3

14 6

Ritalin

Novartis

Phase 3

2 7

Statin

Bristol-Myers Squibb

Phase 3

1 8

Semaglutide Pen Injector

UUniversitaire Ziekenhuizen KU Leuven

Phase 3

1 9

INR101

YYunhe Pharmaceutical (Tianjin) Co., Ltd

Phase 3

3 10

Trexall

Jazz Pharmaceuticals

Preclinical

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Recruiting

Statin

NCT07344610

Post-ApprovalRecruiting

Optical Coherence Tomography

NCT06520904

N/ANot yet recruiting

Coronary Artery Bypass

NCT06730802

PreclinicalActive, not recruiting

Prostate Cancer

NCT03127631

Q4 2027

Recruiting

Ischemic Stroke

NCT06604117

N/ANot yet recruiting

Acute Coronary Syndrome

NCT06096909

Clinical

Trials by Indication[1]

Acute Coronary Syndrome4 trials

Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population

Not yet recruiting·CChina National Center for Cardiovascular Diseases·N/A·NCT06096909·3,684 enrolled

Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome

Unknown status·XXijing Hospital·Phase 4·NCT01372839·300 enrolled

Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS)

Recruiting·YYun Dai Chen··NCT06738758·6,000 enrolled

Show 1 more trial

Low-dose PCSK9 Inhibitor Combined With Stains on Serum Lipids in Chinese Population With Acute Coronary Syndrome

Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 4·NCT05298475·100 enrolled

Ischemic stroke3 trials

The Benefit of Add On DLBS1033 for Ischemic Stroke Patient

Unknown status·—·Phase 2/3·NCT04425590·180 enrolled

Efficacy of Probucol Combined with Statins Treatment for Ischemic Stroke

Recruiting·XXuanwu Hospital, Beijing··NCT06604117·200 enrolled

AdminiStration of Statin On Acute Ischemic stRoke patienT Trial

Completed·HHyogo Medical University·Phase 4·NCT02549846·270 enrolled

Coronary Artery Disease3 trials

Rosuvastatin and Evolocumab for Coronary Artery Disease

Completed·IIcahn School of Medicine at Mount Sinai··NCT05984953·195 enrolled

Intensive Statin Treatment in Chinese Coronary Artery Disease Patients Undergoing PCI

Completed·PPeking University First Hospital·Phase 4·NCT01293097·2,884 enrolled

Effect of Berberine for Endothelial Function and Intestinal Microflora in Patients With Coronary Artery Disease

Unknown status·PPeking Union Medical College Hospital·Phase 1/2·NCT04434365·24 enrolled

Atherosclerosis3 trials

Efficacy Study of p38 Kinase Inhibitor to Treat Patients With Atherosclerosis

Completed· Bristol-Myers Squibb logo

Bristol-Myers Squibb·Phase 2·NCT00570752·72 enrolled

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Recruiting·TTongji Hospital··NCT04847752·1,000 enrolled

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

Recruiting·PPeking Union Medical College Hospital·Phase 4·NCT06902740·300 enrolled

Statin3 trials

Real World Evidence Study of Statin Use in Brazil

Completed·HHospital Israelita Albert Einstein··NCT05285085·2,133,900 enrolled

Statin With Palliative Therapy for HCC

Terminated·TTaipei Medical University WanFang Hospital·N/A·NCT02785874·4 enrolled

Effects of Short-term Intensive Statin Therapy on Lipid Levels

Recruiting·GGeneral Hospital of Shenyang Military Region··NCT07344610·800 enrolled

48 more indications

Stroke2 trials

Carotid Intima-media Thickness in Japan Statin Treatment Against Recurrent Stroke(J-STARS Echo)

Completed·TTranslational Research Center for Medical Innovation, Kobe, Hyogo, Japan·Phase 3·NCT00361530·854 enrolled

hsCRP in Japan Statin Treatment Against Recurrent Stroke (J-STARS hsCRP)

Completed·TTranslational Research Center for Medical Innovation, Kobe, Hyogo, Japan·Phase 3·NCT00361699·1,095 enrolled

Transient Ischemic Attack2 trials

Statins in Frail Older Patients with Ischemic Stroke or Transient Ischemic Attack - the Prospective Cohort Study

Recruiting·—··NCT06785740·300 enrolled

StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial

Not yet recruiting·PProf. dr. Nathalie van der Velde·Phase 4·NCT06785727·612 enrolled

Statins2 trials

A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of Statins

Completed· Pfizer logo

Pfizer·Phase 2·NCT01342211·93 enrolled

Evaluation of the LDL-C Lowering Effects of Ezetimibe Achieved in Co-administration Therapy With Statins in an Indonesian Population (Study P04276)(COMPLETED)

Completed·OOrganon and Co··NCT00705081·453 enrolled

Type 2 Diabetes2 trials

CHOlesterol Lowering and Residual Risk in Type 2 Diabetes

Completed·NNYU Langone Health·Phase 4·NCT04369664·151 enrolled

Simvastatin Reduces Circulating Osteoprotegerin Levels in Patients With Type 2 Diabetes

Completed·UUniversity of Aarhus·Phase 4·NCT00471549·18 enrolled

Hyperlipidemia2 trials

Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia

Completed·CCatabasis Pharmaceuticals·Phase 2·NCT01912560·99 enrolled

Comparison of SLx-4090 Combined With Statin Therapy Versus Statin Alone in Reducing LDL-C in Patients With Hyperlipidemia

Completed·RResponse Pharmaceuticals·Phase 2·NCT00810979·133 enrolled

Hypercholesterolemia2 trials

Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1)

Completed· Regeneron logo

Regeneron·Phase 3·NCT01926782·803 enrolled

A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173)

Completed·OOrganon and Co·Phase 3·NCT03882905·769 enrolled

Trial2 trials

Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial).

Active, not recruiting·FFondazione Policlinico Universitario Agostino Gemelli IRCCS·Phase 4·NCT05122780·120 enrolled

ANti-Oxidant in Variant Angina (ANOVA) Trial

Unknown status·SSeoul National University Hospital·Phase 4·NCT03228238·300 enrolled

Heart Disease2 trials

Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Unknown status·ZZibo Central Hospital·Phase 4·NCT05802108·60 enrolled

Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)

Completed·OOrganon and Co··NCT00730132·712 enrolled

Treatment1 trial

HCV Treatment With Fluvastatin, Simvastatin to Improve Interferon Sensitivity

Terminated·—·Phase 1·NCT01377909·20 enrolled

Intracerebral Hemorrhage1 trial

Statin for Neuroprotection in Spontaneous Intracerebral Hemorrhage

Unknown status·—·Phase 2/3·NCT04857632·98 enrolled

Cardiovascular1 trial

Low-density Lipoprotein Cholesterol Reduction With State-of-the-art Therapy in Secondary Prevention and Major Cardiovascular Adverse Events: Republic of Srpska Registry

Unknown status·UUniversity Clinical Centre of Republic of Srpska··NCT05081336·500 enrolled

Carotid Endarterectomy1 trial

Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes

Completed·—·Phase 3·NCT02850081·31 enrolled

Mitochondria1 trial

Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS

Completed·—·N/A·NCT01702987·22 enrolled

Optical Coherence Tomography1 trial

Effect of PCSK9 Inhibitors on Coronary Atherosclerotic Plaques Derived From Optical Coherence Tomography

Recruiting·—·Phase 4·NCT06520904·396 enrolled

Cardiorespiratory Fitness1 trial

The Association of Statins on Cardiorespiratory Fitness and Exercise Adaptation

Completed·UUniversity of Sao Paulo General Hospital··NCT04986241·18,557 enrolled

Immunity1 trial

Effect of Statins on Trained Immunity

Completed·RRadboud University Medical Center··NCT02817230·45 enrolled

Chemotherapy1 trial

Statins Effect on Incidence of Side Effects of Platinum Based Chemotherapy

Completed·MMinia University·Phase 1/2·NCT06553157·56 enrolled

Atrial Fibrillation1 trial

The Effects of Renal Function and Atrial Fibrillation on Lipoproteins and Clot Structure/Function

Terminated·UUniversity of Liverpool··NCT04043026·56 enrolled

Cardiogenic Shock1 trial

Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients

Completed·TTarumanagara University··NCT03596944·145 enrolled

Heart Failure1 trial

Study to Evaluate the Effectiveness of High Dose Statin Loading in Acute Heart Failure Patients

Completed·YYonsei University·N/A·NCT01127945·50 enrolled

Pacemaker1 trial

Statin and PAF in Patients With Pacemaker

Unknown status·NNational Taiwan University Hospital·N/A·NCT00201552

Endothelial Function1 trial

Endothelial Function Evaluation in Patients With PAOD Treated With Sulodexide + Conventional Treatment (CT) Vs CT Alone

Unknown status·AAlfa Wassermann Tunisia·Phase 3·NCT03370705·156 enrolled

Insulin Sensitivity1 trial

Effects of Atorvastatin on Adiponectin Levels and Insulin Sensitivity In Hypercholesterolemic Patients

Completed·GGachon University Gil Medical Center·Phase 4·NCT00745836

Subarachnoid Hemorrhage1 trial

The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage

Unknown status·UUniversity of Sao Paulo General Hospital·Phase 4·NCT01346748·80 enrolled

Hepatocellular Carcinoma1 trial

Effects of Statin on Hepatocellular Carcinoma Recurrence After Liver Transplantation

Completed·YYonsei University··NCT03490461·350 enrolled

COVID-191 trial

The Impact of Statin Therapy in the Covid-19 Patients

Completed·—··NCT05238402·707 enrolled

Type 1 Diabetes1 trial

Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial

Completed·UUniversity of Cambridge·Phase 3·NCT01581476·443 enrolled

Ovarian Cancer1 trial

An Exploratory Clinical Study of Statins for Improving Chemotherapy and Maintenance in Patients With Ovarian Cancer

Recruiting·—·Phase 2·NCT06468254·500 enrolled

Cholesterol1 trial

A Study of LY3015014 in Participants With High Cholesterol

Completed· Eli Lilly logo

Eli Lilly·Phase 2·NCT01890967·527 enrolled

Metabolic Syndrome1 trial

Exercise, Statins, and the Metabolic Syndrome

Completed·UUniversity of Kansas Medical Center·N/A·NCT01700530·121 enrolled

Acute Pancreatitis1 trial

Statins and Post-ERCP Acute Pancreatitis (Stark Project)

Completed·—··NCT06367322·1,016 enrolled

Obstructive Sleep Apnea1 trial

The Endothelium Dysfunction in Patients of Obstructive Sleep Apnea Syndrome

Completed·—·Phase 4·NCT01699126·46 enrolled

Lipid Disorder1 trial

Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

Recruiting·WWake Forest University Health Sciences·Phase 2·NCT06488105·130 enrolled

Non-Alcoholic Fatty Liver Disease1 trial

Empagliflozin Versus Statins in Non-Alcoholic Fatty Liver Disease

Not yet recruiting·—·Phase 4·NCT07180745·400 enrolled

Coronary Artery Bypass1 trial

Protective Effect of PCSK9 Inhibitor Against Negative Inflammatory Response and Organ Dysfunction After Coronary Artery Bypass Grafting (PANDA VIII)

Not yet recruiting·NNanjing Medical University·N/A·NCT06730802·400 enrolled

TED1 trial

Compliance With LDL-Lowering Therapy (Study P05467)(COMPLETED)

Completed·OOrganon and Co··NCT00723723·555 enrolled

PCSK9 Inhibitor1 trial

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Unknown status·XXiang Xie·Phase 4·NCT05976893·620 enrolled

Injury1 trial

A Project to Improve the Diagnosis and Prognosis of Myocardial Injury Associated to Non Cardiac Surgery

Completed·PParc de Salut Mar··NCT03133260·800 enrolled

Efficacy1 trial

Red Rice Yeast in Low-density Lipoprotein (LDL) Lowering: an Efficacy Study

Unknown status·SSaint-Joseph University·Phase 2·NCT03607383·40 enrolled

Hypertriglyceridemia1 trial

Lipid-lowering Effects of Gefarnate in Statin-treated Coronary Heart Disease Patients With Residual Hypertriglyceridemia

Unknown status·FFirst Affiliated Hospital of Harbin Medical University·Phase 2/3·NCT03610321·70 enrolled

Atherosclerotic Plaque1 trial

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP)

Withdrawn·UUniversity of Louisville·Phase 4·NCT06280976

Chronic Total Occlusion1 trial

Effect of Evolocumab on Chronic Total Occlusions (EVOLO-CTO)

Unknown status·LLin Zhao·Phase 4·NCT05623995·200 enrolled

Cardiovascular Disease1 trial

High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program

Unknown status·UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology·N/A·NCT05782881·16,000 enrolled

Prognosis1 trial

Epidemiology, Management, Prognosis and Medical Cost Analysis of IHCA and OHCA

Completed·NNational Taiwan University Hospital··NCT03684616·100,000 enrolled

Arterial Stiffness1 trial

The Effect of Anacetrapib on Vascular Function and Arterial Stiffness

Completed·—··NCT02931188·103 enrolled

Sudden Sensorineural Hearing Loss1 trial

Towards a Self-Administered Hearing Protection Regimen

Terminated·NNorthwestern University·Approved·NCT04826237·3 enrolled

Menopausal Complaints1 trial

The Role of STAtins in Reversing Coagulation Profile Changes Induced by Hormone Replacement Therapy in Menopausal Women With Hypercholesterolemia: the STAR-HRT Study

Recruiting·UUniversity of Pisa··NCT07742488·70 enrolled

Prostate Cancer1 trial

The Role of Androgen Deprivation Therapy In Cardiovascular Disease - A Longitudinal Prostate Cancer Study (RADICAL PC1) & A Randomized Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (RADICAL PC2)

Active, not recruiting·MMcMaster University·Preclinical·NCT03127631·5,000 enrolled

Sources

References

[1]
ClinicalTrials.gov — 72 trial records for Statin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Statin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Statin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Bristol-Myers Squibb company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: Bristol-Myers Squibb

Statin

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Q4 2027

Trials by Indication[1]

Acute Coronary Syndrome4 trials

Ischemic stroke3 trials

Coronary Artery Disease3 trials

Atherosclerosis3 trials

Statin3 trials

Stroke2 trials

Transient Ischemic Attack2 trials

Statins2 trials

Type 2 Diabetes2 trials

Hyperlipidemia2 trials

Hypercholesterolemia2 trials

Trial2 trials

Heart Disease2 trials

Treatment1 trial

Intracerebral Hemorrhage1 trial

Cardiovascular1 trial

Carotid Endarterectomy1 trial

Mitochondria1 trial

Optical Coherence Tomography1 trial

Cardiorespiratory Fitness1 trial

Immunity1 trial

Chemotherapy1 trial

Atrial Fibrillation1 trial

Cardiogenic Shock1 trial

Heart Failure1 trial

Pacemaker1 trial

Endothelial Function1 trial

Insulin Sensitivity1 trial

Subarachnoid Hemorrhage1 trial

Hepatocellular Carcinoma1 trial

COVID-191 trial

Type 1 Diabetes1 trial

Ovarian Cancer1 trial

Cholesterol1 trial

Metabolic Syndrome1 trial

Acute Pancreatitis1 trial

Obstructive Sleep Apnea1 trial

Lipid Disorder1 trial

Non-Alcoholic Fatty Liver Disease1 trial

Coronary Artery Bypass1 trial

TED1 trial

PCSK9 Inhibitor1 trial

Injury1 trial

Efficacy1 trial

Hypertriglyceridemia1 trial

Atherosclerotic Plaque1 trial

Chronic Total Occlusion1 trial

Cardiovascular Disease1 trial

Prognosis1 trial

Arterial Stiffness1 trial

Sudden Sensorineural Hearing Loss1 trial

Menopausal Complaints1 trial

Prostate Cancer1 trial

References

Drug Info

Quick Facts

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