leucine

PreclinicalSmall molecule

NNational Center for Research Resources (NCRR)

leucine is one of 83 small molecule programs targeting Anemia. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

AnemiaActive, not recruiting

Necrotizing EnterocolitisActive, not recruiting

Cystic FibrosisActive, not recruiting

AnemiaPhase 1/Phase 2

Active, not recruiting

Necrotizing EnterocolitisPreclinical

Active, not recruiting

Cystic FibrosisPreclinical

Active, not recruiting

Competition

Competitive Landscape

386 competitors in Cystic Fibrosis

#DrugCompanyPhaseTrials

Onglyza

AstraZeneca

Preclinical

2 2

Calciferol

Alnylam Pharmaceuticals

Preclinical

1 3

Vibramycin

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

3 4

Actimmune

HHorizon Therapeutics Ireland DAC

Preclinical

2 5

Proair HFA

GGlaxo Dba Glaxosmithkline

Preclinical

2 6

Aztreonam Lysine

Gilead

Preclinical

5 7

Amitiza

SSucampo Pharma Americas, LLC

Preclinical

1 8

Capromorelin

UUniversity of Aarhus

Preclinical

1 9

Advil

KKenvue Brands

Preclinical

1 10

Feosol

AAuerbach Hematology Oncology Associates P C

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Low Birth Weight1 trial

Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion

Unknown status·NNational Center for Research Resources (NCRR)·N/A·NCT00005889·96 enrolled

Cystic Fibrosis1 trial

Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis

Terminated·NNational Center for Research Resources (NCRR)··NCT00014768·36 enrolled

Anemia1 trial

Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia

Completed·NNorthwell Health·Phase 1/2·NCT01362595·55 enrolled

Necrotizing Enterocolitis1 trial

Collaborative Research Group for Necrotizing Enterocolitis

Completed·WWashington University School of Medicine·N/A·NCT00828451·29 enrolled

Sources

References

[1]
ClinicalTrials.gov — 4 trial records for leucine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — leucine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for leucine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — National Center for Research Resources (NCRR) company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: NNational Center for Research Resources (NCRR)

leucine

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Low Birth Weight1 trial

Cystic Fibrosis1 trial

Anemia1 trial

Necrotizing Enterocolitis1 trial

References

Drug Info

Quick Facts

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