LGT209

Phase 1Small molecule

Novartis

LGT209 is one of 37 small molecule programs targeting Hypercholesterolemia. It is currently in Phase 1.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

HypercholesterolemiaActive, not recruiting

HypercholesterolemiaPhase 1

Active, not recruiting

Competition

Competitive Landscape

130 competitors in Hypercholesterolemia

#DrugCompanyPhaseTrials

Lescol

Novartis

Phase 3

1 2

Micardis

Boehringer Ingelheim

Phase 3

1 3

Comparator: Statins

Merck & Co.

Phase 3

3 4

Comparator: Pbo

Merck & Co.

Phase 3

2 5

Evacetrapib

Eli Lilly

Phase 3

2 6

Kynamro

KKastle Therapeutics, LLC

Phase 3

1 7

Enlicitide

Merck & Co.

Phase 3

3 8

Anacetrapib

Merck & Co.

Phase 3

1 9

Lapaquistat Acetate

Takeda

Phase 3

9 10

Bococizumab

Pfizer

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Hypercholesterolemia1 trial

Safety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With Hypercholesterolemia

Completed· Novartis logo

Novartis·Phase 1·NCT01979601·74 enrolled

Elevated Cholesterol1 trial

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Completed· Novartis logo

Novartis·Phase 1·NCT01859455·25 enrolled

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for LGT209. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — LGT209 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for LGT209. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Novartis company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 1[1]
Company: Novartis

LGT209

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Hypercholesterolemia1 trial

Elevated Cholesterol1 trial

References

Drug Info

Quick Facts

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