Lumason

ApprovedSmall molecule

BBracco Diagnostics, Inc

Lumason is one of 206 small molecule programs targeting Stroke. It is currently in Approved.

Indications

Total Trials

Active Trials

205

Competitors

Pipeline

Status by Indication[3][1]

Indication

StrokeActive, not recruiting

Diffuse Intrinsic Pontine GliomaNot yet recruiting

Breast CancerActive, not recruiting

Hepatocellular CarcinomaActive, not recruiting

GlioblastomaActive, not recruiting

Glioblastoma MultiformeActive, not recruiting

LymphedemaActive, not recruiting

StrokePhase 1

Active, not recruiting

Diffuse Intrinsic Pontine GliomaPhase 1

Not yet recruiting

Breast CancerPhase 1

Active, not recruiting

Hepatocellular CarcinomaApproved

Active, not recruiting

GlioblastomaPreclinical

Active, not recruiting

Glioblastoma MultiformePhase 1/Phase 2

Active, not recruiting

LymphedemaPhase 1

Active, not recruiting

Competition

Competitive Landscape

2828 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Lumason

BBracco Diagnostics, Inc

Approved

2 2

Tykerb

GSK

Preclinical

80 3

Prolia

Amgen

Preclinical

14 4

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

3 5

Spravato

WWim Janssens

Preclinical

2 6

Perflutren Lipid Microsphere

IImaRx Therapeutics

Preclinical

1 7

Dextromethorphan Hydrobromide

Boehringer Ingelheim

Preclinical

1 8

Perflutren Lipid Microcpheres

TThomas Jefferson University

Preclinical

2 9

Tianeptine

Pfizer

Preclinical

1 10

Systemic Treatment

TTaproot Health

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Phase 3Recruiting

Infusion

NCT06400004

Q1 2027

Phase 1/2Not yet recruiting

Glioblastoma Multiforme

NCT06329570

Q4 2027

Phase 1Not yet recruiting

Alzheimer's Disease

NCT06600880

Q2 2029

N/ANot yet recruiting

Glioblastoma

NCT07274787

Clinical

Trials by Indication[1]

Safety and Efficacy2 trials

Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-141

Completed·BBracco Diagnostics, Inc·Phase 3·NCT02522481·175 enrolled

Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-142

Completed·BBracco Diagnostics, Inc·Phase 3·NCT02552238·174 enrolled

Breast Cancer2 trials

Pilot Study to Evaluate if Contrast Enhanced Ultrasound (CEUS) Can Predict Treatment Response in Triple Negative Breast Cancer (TNBC) Patients Receiving Combined Chemotherapy and Immune Checkpoint Inhibitors (ICI).

Withdrawn·MMilton S. Hershey Medical Center·Phase 1·NCT05957042

Comparison of Three Methods for Early Detection of Breast Cancer

Completed·MMayo Clinic·Phase 1·NCT03954015·3 enrolled

Alzheimer's Disease1 trial

Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau

Not yet recruiting·—·Phase 1·NCT06600880·6 enrolled

Glioblastoma1 trial

Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma

Not yet recruiting·UUniversity of Cincinnati·N/A·NCT07274787·10 enrolled

Hepatocellular Carcinoma1 trial

Accuracy of Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma Post TACE

Completed·MMilton S. Hershey Medical Center·Phase 4·NCT04569799·26 enrolled

9 more indications

Infusion1 trial

Lumason® Infusion vs. Bolus Administrations

Recruiting·BBracco Diagnostics, Inc·Phase 3·NCT06400004·106 enrolled

Stroke1 trial

Study: SONAS Ultrasound for Detecting Stroke SONAS Ultrasound for Detecting Stroke

Completed·UUniversity of California, Los Angeles·Phase 1·NCT03296852·12 enrolled

Ultrasound1 trial

Contrast Ultrasound for Pediatric Trauma - Comparative Evaluation (CAPTURE Study)

Completed·DDavid Mooney·Phase 1/2·NCT04718441·68 enrolled

Lymphedema1 trial

Contrast-Enhanced Ultrasound and Shear Wave Elastography for the Treatment of Lymphedema

Completed·MMayo Clinic·Phase 1·NCT05613946·10 enrolled

Scar1 trial

Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)

Unknown status·—·Phase 1·NCT03653702·70 enrolled

Glioblastoma Multiforme1 trial

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

Not yet recruiting·NNaviFUS Corporation·Phase 1/2·NCT06329570·10 enrolled

Abdominal Injuries1 trial

Contrast-Enhanced Ultrasound in the Evaluation of Abdominal Injuries in Children

Terminated·DDavid Mooney·Phase 1/2·NCT03147690·74 enrolled

Intraoperative1 trial

Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH

Recruiting·—·Phase 1·NCT03107520·125 enrolled

Diffuse Intrinsic Pontine Glioma1 trial

A Safety and Feasibility Study of NeuroNavigation-Guided Low Intensity Focused Ultrasound With Microbubbles to Enhance Nivolumab Delivery for the Treatment of Relapsed and Progressive Diffuse Midline Glioma and Other High Grade Brain Tumors

Not yet recruiting·CChildren's National Research Institute·Phase 1·NCT07664176·30 enrolled

Sources

References

[1]
ClinicalTrials.gov — 16 trial records for Lumason. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Lumason compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Lumason. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Bracco Diagnostics, Inc company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: BBracco Diagnostics, Inc

Lumason

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Q1 2027

Q4 2027

Q2 2029

Trials by Indication[1]

Safety and Efficacy2 trials

Breast Cancer2 trials

Alzheimer's Disease1 trial

Glioblastoma1 trial

Hepatocellular Carcinoma1 trial

Infusion1 trial

Stroke1 trial

Ultrasound1 trial

Lymphedema1 trial

Scar1 trial

Glioblastoma Multiforme1 trial

Abdominal Injuries1 trial

Intraoperative1 trial

Diffuse Intrinsic Pontine Glioma1 trial

References

Drug Info

Quick Facts

Related News