Mesalazine

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Safety and EfficacyUlcerative ColitisProctitisDiverticular Disease

130 competitors in Safety and Efficacy

#DrugCompanyPhaseTrials

1

Avastin

Roche

Phase 3

32

Actemra

Roche

Phase 3

13

Humira

RRanbaxy Laboratories Limited

Phase 3

34

Rayos

RRoxane Laboratories

Phase 3

35

Empaveli

Apellis Pharmaceuticals

Phase 3

26

Gemzar

Johnson & Johnson

Phase 2

67

Fludara

Sanofi

Phase 2

58

CAB LA

GSK

Phase 3

19

Tagrisso

AstraZeneca

Phase 2

310

Yervoy

Bristol-Myers Squibb

Phase 2

3Show 39 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Ulcerative Colitis17 trials

Budesonide Capsules Versus Mesalazine Granules in Active Ulcerative Colitis (UC)

Completed·—·Phase 3·NCT00747110·343 enrolled

Adherence of a 1.600 mg Single Tablet 5-ASA Treatment of Ulcerative Colitis

Unknown status·FFlemming Bendtsen·Phase 4·NCT04133194·200 enrolled

Effectiveness of Fecal Microbiota Transplantation as add-on Therapy in Mild-to-moderate Ulcerative Colitis

Completed·—·N/A·NCT05538026·53 enrolled

Show 14 more trials

Induction and Maintenance of Remission With Pentasa as Ulcerative Colitis Treatment

Completed·Ferring··NCT02261636·150 enrolled

Aminosalicylic Acid Withdrawal Study in Long Standing Inactive Ulcerative Colitis

Completed·—·N/A·NCT02537210·177 enrolled

Efficacy and Safety of Two Doses of SPD476 (Mesalazine) 2.4g and 4.8g Once Daily, With Reference to Asacol 0.8g Three Times Daily in Subjects With Acute, Mild to Moderate Ulcerative Colitis

Completed·Takeda·Phase 3·NCT00548574·343 enrolled

Mesalazine With Hydrocortisone Sodium Succinate Enema for 4-Week Treatment in Patients With Ulcerative Colitis

Unknown status·XXijing Hospital of Digestive Diseases·Phase 4·NCT03110198·528 enrolled

Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis

Unknown status·SSixth Affiliated Hospital, Sun Yat-sen University·Phase 4·NCT05205603·438 enrolled

Minocyclin in Ulcerative Colitis as Added on Therapy

Completed·MMostafa Bahaa·Phase 2·NCT06201793·46 enrolled

Comparative Efficacy and Safety Study in Patients With Ulcerative Colitis in Remission Phase

Completed·TTillotts Pharma AG·Phase 3·NCT01257399·251 enrolled

OD vs. TID Dosing With Mesalazine Granules in Active Ulcerative Colitis

Completed·—·Phase 3·NCT00449722·380 enrolled

A Phase II Study to Explore the Safety and Activity of Dersalazine in Patients With Mild to Moderate Ulcerative Colitis

Completed·PPalau Pharma S.L.U.·Phase 2·NCT00808977·80 enrolled

Comparative Efficacy and Safety Study in Patients With Active Ulcerative Colitis

Completed·TTillotts Pharma AG·Phase 3·NCT01257386·251 enrolled

To Evaluate the Efficacy and Safety of FE 999315 in Japanese Subjects With Mild to Moderate Active Ulcerative Colitis

Completed·Ferring·Phase 3·NCT03412682·274 enrolled

Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis

Unknown status·RResearch Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan·Phase 1/2·NCT03441893·300 enrolled

Phase III Multicentre Trial of Oral Mesalazine in Patients With Mild to Moderate Ulcerative Colitis.

Unknown status·FFaes Farma, S.A.·Phase 3·NCT06176560·376 enrolled

Efficacy of Acupuncture Combined With Mesalazine in Inducing and Maintaining Clinical Remission in Mild-to-Moderate Active Ulcerative Colitis: A Single-Center, Randomized Controlled Clinical Trial.

Recruiting·QQin Yu·Preclinical·NCT07389824·66 enrolled

Irritable Bowel Syndrome4 trials

Mesalazine Therapy in Patients With Irritable Bowel Syndrome

Completed·SSOFAR S.p.A.·Phase 3·NCT00626288·187 enrolled

A Randomized Controlled Pilot Trial of Mesalazine in Patients With Irritable Bowel Syndrome

Completed·SSOFAR S.p.A.·Phase 2/3·NCT00774007·20 enrolled

Effects of Mesalamine and Amitriptyline on Irritable Bowel Syndrome

Withdrawn·TTehran University of Medical Sciences·Phase 4·NCT02190526

Show 1 more trial

Mesalazine for the Treatment of Diarrhoea-predominant Irritable Bowel Syndrome (IBS-D)

Completed·UUniversity of Nottingham·Phase 4·NCT01316718·108 enrolled

Crohn's Disease3 trials

Preventing Postoperative Relapse in Crohn's Disease Patients at Risk: Azathioprine Versus Mesalazine

Completed·—·Phase 3·NCT00946946·78 enrolled

The Effect on Mucosal Healing With Pentasa Sachet in Mild to Moderate Active "Drug: Crohn's Disease"

Terminated·Ferring·Phase 3·NCT00245505·3 enrolled

Phase III Study of D9421-C 9 mg in Patients With Active Crohn's Disease in Japan

Completed·AstraZeneca·Phase 3·NCT01514240·123 enrolled

Proctitis2 trials

QUality of Life in pAtients With Mild to modeRate Active procTitis Treated by mesalaZine (Pentasa®)

Completed·Ferring··NCT02368743·117 enrolled

Budesonide vs. Mesalazine vs. Budesonide/Mesalazine Suppository Combination Therapy in Acute Ulcerative Proctitis

Completed·—·Phase 2·NCT01966783·320 enrolled

Diverticulitis2 trials

Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis

Terminated·—·Phase 3·NCT00695643·345 enrolled

Two Doses Mesalazine Granules Versus Placebo for the Prevention of Recurrence of Diverticulitis

Terminated·—·Phase 3·NCT01038739·330 enrolled

Details

Drug Info

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