Nor-epinephrine

PreclinicalSmall molecule

NNational Hepatology & Tropical Medicine Research Institute

Nor-epinephrine is one of 4 small molecule programs targeting Hepatorenal Syndrome. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Hepatorenal SyndromeActive, not recruiting

Post Spinal Anaesthesia HypotensionNot yet recruiting

Hepatorenal SyndromePreclinical

Active, not recruiting

Post Spinal Anaesthesia HypotensionPreclinical

Not yet recruiting

Competition

Competitive Landscape

7 competitors in Hepatorenal Syndrome

#DrugCompanyPhaseTrials

Glypressin

MMallinckrodt

Approved

12 2

Letairis

Gilead

Phase 2

1 3

Sandostatin

Sun Pharma

Preclinical

2 4

Nor-epinephrine

NNational Hepatology & Tropical Medicine Research Institute

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

PreclinicalNot yet recruiting

Post Spinal Anaesthesia Hypotension

NCT07706426

Clinical

Trials by Indication[1]

Hepatorenal Syndrome1 trial

Nor-epinephrine Versus Midodrine/Octreotide in Patients With Hepatorenal Syndrome

Completed·NNational Hepatology & Tropical Medicine Research Institute·N/A·NCT04522297·91 enrolled

Post Spinal Anaesthesia Hypotension1 trial

Effect of Maternal Body Mass Index on the Prophylactic Dose of Norepinephrine Infusion for Preventing Hypotension in Parturient After Spinal Anesthesia

Not yet recruiting·AAin Shams University·Preclinical·NCT07706426·80 enrolled

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for Nor-epinephrine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Nor-epinephrine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Nor-epinephrine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — National Hepatology & Tropical Medicine Research Institute company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: NNational Hepatology & Tropical Medicine Research Institute

Nor-epinephrine

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2027

Trials by Indication[1]

Hepatorenal Syndrome1 trial

Post Spinal Anaesthesia Hypotension1 trial

References

Drug Info

Quick Facts

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