Oxalobacter formigenes

Phase 2Biologic

OOxThera

Oxalobacter formigenes is one of 7 biologic programs targeting Primary Hyperoxaluria. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Primary HyperoxaluriaActive, not recruiting

Primary HyperoxaluriaPhase 2

Active, not recruiting

Competition

Competitive Landscape

11 competitors in Primary Hyperoxaluria

#DrugCompanyPhaseTrials

Givlaari

Alnylam Pharmaceuticals

Cystadane

1 3

Diacomit

BBiocodex

Phase 2

1 4

Oxalobacter formigenes

OOxThera

Phase 2

2 5

ALLN-177

AAllena Pharmaceuticals

Phase 2

1 6

DCR-PHXC

DDicerna Pharmaceuticals, Inc., a Novo Nordisk company

Phase 1

2 7

YOLT-203

RRenJi Hospital

Phase 1

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Primary Hyperoxaluria2 trials

Study to Evaluate the Efficacy and Safety of Oxabact (OC5) in Primary Hyperoxaluria Patients Who Are on Dialysis

Completed·OOxThera·Phase 2·NCT02000219·12 enrolled

Study to Evaluate the Efficacy and Safety of OxabactTM on Reduction of Urinary Oxalate in Primary Hyperoxaluria Patients

Completed·OOxThera·Phase 2/3·NCT00638703·43 enrolled

Phase 21 trial

Phase 2/3 Oxabact Study

Completed·OOxThera·Phase 2/3·NCT01037231·36 enrolled

Sources

References

[1]
ClinicalTrials.gov — 3 trial records for Oxalobacter formigenes. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Oxalobacter formigenes compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Oxalobacter formigenes. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — OxThera company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Biologic[2]
Highest Phase: Phase 2[1]
Company: OOxThera

Oxalobacter formigenes

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Primary Hyperoxaluria2 trials

Phase 21 trial

References

Drug Info

Quick Facts

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