Progestin

Phase 3Small molecule

WWashington University School of Medicine

Progestin is one of 9 small molecule programs targeting Ovarian cyst. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Ovarian CystActive, not recruiting

Ovarian CystPhase 3

Active, not recruiting

Competition

Competitive Landscape

11 competitors in Ovarian Cyst

#DrugCompanyPhaseTrials

Neo-Synephrine

EExela Pharma Sciences, LLC.

Approved

—2

Brevibloc

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Approved

—3

Naropin

FFresenius Kabi Oncology Ltd.

Approved

—4

Norethisterone Acetate

MMansoura University

Approved

1 5

Depot Medroxyprogesterone Acetate

AbbVie

Phase 2

1 6

Combined Oral Contraceptive Pills

WWoman's Health University Hospital, Egypt

Phase 3

1 7

Gynorest

SSolvay Pharmaceuticals

Phase 1

1 8

Progestin

WWashington University School of Medicine

Phase 3

1 9

Femara

Novartis

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

Post-ApprovalNot yet recruiting

Ovarian Stimulation

NCT06396390

Q4 2029

Phase 2Recruiting

Study completion

NCT05903131

Clinical

Trials by Indication[1]

Ovarian Stimulation1 trial

Comparison of Progestin Primed Ovarian Stimulation (PPOS) vs.GnRH Antagonist Methods on IVF Outcomes

Not yet recruiting·NNesta Clinic·Phase 4·NCT06396390·152 enrolled

Ovarian cyst1 trial

Treat of Functional Ovarian Cysts by Compare Between Cocs and Progesterone Only Pills

Unknown status·SSohag University·Phase 3·NCT05244811·60 enrolled

Endometrial1 trial

Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)

Terminated·UUniversity of Illinois at Chicago·N/A·NCT01718444·27 enrolled

Ovulation Induction1 trial

Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate

Withdrawn·UUniversity of British Columbia·Phase 4·NCT01966575

Unspecified2 trials

Regulation of Cervical Mucus Secretion

Completed·OOregon Health and Science University·Phase 4·NCT02969590·5 enrolled

Uterine Preservation Via Lifestyle Transformation

Recruiting·WWashington University School of Medicine·Phase 2·NCT05903131·96 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Progestin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Progestin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Progestin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Washington University School of Medicine company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: WWashington University School of Medicine

Progestin

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2026

Q4 2029

Trials by Indication[1]

Ovarian Stimulation1 trial

Ovarian cyst1 trial

Endometrial1 trial

Ovulation Induction1 trial

Unspecified2 trials

References

Drug Info

Quick Facts

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