R-miniCHOP

Phase 3Small molecule

UUniversität des Saarlandes

R-miniCHOP is one of 52 small molecule programs targeting Diffuse Large B-Cell Lymphoma. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Diffuse Large B-Cell LymphomaActive, not recruiting

Large B-Cell LymphomaRecruiting

DLBCL - Diffuse Large B Cell LymphomaNot yet recruiting

Diffuse Large B-Cell LymphomaPhase 3

Active, not recruiting

Large B-Cell LymphomaPhase 3

Recruiting

DLBCL - Diffuse Large B Cell LymphomaPhase 2

Not yet recruiting

Competition

Competitive Landscape

332 competitors in Diffuse Large B-Cell Lymphoma

#DrugCompanyPhaseTrials

Rituxan

Eloxatin

17 3

Rayos

RRoxane Laboratories

Phase 3

57 4

Cytoxan

BBaxter Healthcare Corporation

Phase 3

68 5

Revlimid

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 3

29 6

COLUMVI

Roche

Phase 3

10 7

Cytosar

Teva

Phase 3

9 8

Vepesid

AAvyxa

Phase 3

22 9

Adcetris

Pfizer

Phase 3

6 10

Adriamycin

GGynecologic Oncology Group

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2029

Phase 3Recruiting

Large B-Cell Lymphoma

NCT05820841

Q4 2031

Phase 2Not yet recruiting

DLBCL - Diffuse Large B Cell Lymphoma

NCT07677813

Clinical

Trials by Indication[1]

DLBCL - Diffuse Large B Cell Lymphoma1 trial

Efficacy and Safety of Orelabrutinib Combined With Induction Therapy Followed by Sequential Monotherapy Maintenance in MCD Subtype Diffuse Large B-cell Lymphoma: a Single-center, Single-arm, Prospective Study

Not yet recruiting·OOu Bai, MD/PHD·Phase 2·NCT07677813·66 enrolled

Large B-cell Lymphoma1 trial

A Randomized, Open-label, Phase 3 Study of Acalabrutinib in Combination With Rituximab and Reduced Dose CHOP (R-miniCHOP) in OldEr Adults With Untreated Diffuse Large B-Cell Lymphoma

Recruiting·UUniversität des Saarlandes·Phase 3·NCT05820841·330 enrolled

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for R-miniCHOP. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — R-miniCHOP compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for R-miniCHOP. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Universität des Saarlandes company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: UUniversität des Saarlandes

R-miniCHOP

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2029

Q4 2031

Trials by Indication[1]

DLBCL - Diffuse Large B Cell Lymphoma1 trial

Large B-cell Lymphoma1 trial

References

Drug Info

Quick Facts

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