recombinant Factor VIII

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Hemophilia aSevere Hemophilia aHemophilia

93 competitors in Hemophilia a

#DrugCompanyPhaseTrials

1

Hemlibra

Roche

Phase 3

162

recombinant Factor VIII

Bayer

Approved

23

Rituxan

Roche

Phase 2

14

Recombinant Human Coagulation FVIII

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 3

25

Eptacog Alfa

Novo Nordisk

Phase 3

16

Qfitlia

GGenzyme, a Sanofi Company

Phase 3

17

Valoctocogene Roxaparvovec

BioMarin Pharmaceutical

Phase 3

38

Rfviia

Roche

Phase 3

19

Marstacimab

Pfizer

Phase 3

110

PF-06741086

Pfizer

Phase 3

1Show 26 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Efficacy and Safety4 trials

EffeKt Taiwan- Efficacy and Safety of Long-term Treatment With KOGENATE® FS in Taiwan

Completed·Bayer··NCT00932555·82 enrolled

Non-interventional Observation of Practical Implementation, Efficacy and Safety of Continuous Infusion With KOGENATE Bayer in Surgery

Completed·Bayer··NCT00922597·26 enrolled

Effekt-2 - Efficacy and Safety of Long-term Treatment With KOGENATE® FS in Latin America

Completed·Bayer··NCT00969319·105 enrolled

Show 1 more trial

EFFEKT - Efficacy and Safety of Long-term Treatment With KOGENATE Bayer/FS

Completed·Bayer··NCT00874926·405 enrolled

Severe Hemophilia a4 trials

Pharmacokinetic Comparison of Advate rAHF-PFM With Recombinate rAHF in Patients With Severe Hemophilia A

Completed·BBaxalta now part of Shire·Phase 4·NCT00666406·9 enrolled

Trial to Evaluate the Effect of Secondary Prophylaxis With rFVIII Therapy in Severe Hemophilia A Adult and/or Adolescent Subjects Compared to That of Episodic Treatment

Completed·Bayer·Phase 3·NCT00623480·84 enrolled

Evaluate Efficacy and Safety of Recombinant Factor VIII （rFVIII）Treatment of Severe or Moderately Severe Hemophilia A

Unknown status·Chia Tai Tianqing Pharmaceutical Group Co., Ltd.·Phase 3·NCT02930317·60 enrolled

Show 1 more trial

Efficacy and Safety Study of Human-cl rhFVIII in PTPs With Severe Hemophilia A

Completed·Octapharma·Phase 3·NCT01125813·32 enrolled

Hemophilia A2 trials

Trial to Evaluate the Efficacy and Safety of a New Full Length Recombinant Human FVIII for Hemophilia A

Completed·Bayer·Phase 3·NCT01029340·74 enrolled

Prophylaxis Versus on Demand Treatment for Children With Hemophilia A

Completed·Bayer·Phase 4·NCT01810666·30 enrolled

MPA1 trial

Comparative Pharmacokinetic Study of Two Different Strengths of BAY14-2222

Completed·Bayer·Phase 1·NCT01653639·18 enrolled

Safety and Efficacy1 trial

BAY81-8973 Pediatric Safety and Efficacy Trial

Completed·Bayer·Phase 3·NCT01311648·94 enrolled

6 more indications

Intravenous1 trial

Pharmacokinetics and Safety of a Single Intravenous Infusion of BAY 79-4980

Completed·Bayer·Phase 1·NCT00629837·27 enrolled

Prophylaxis1 trial

Prophylaxis Versus On-demand Therapy Through Economic Report

Completed·Bayer··NCT01159587·58 enrolled

Haemophilia A1 trial

Validation Study of a cOmputer Pharmacokinetic Tool to assIst in the Follow up Care of haeMophilia A Patients

Completed·Bayer··NCT01436825·69 enrolled

Hemophilia1 trial

Canadian Hemophilia Prophylaxis Study

Completed·TThe Hospital for Sick Children·Phase 4·NCT01085344·56 enrolled

Observational Study1 trial

Extension at 10 Years of the: "Observational Study Evaluating Efficacy and Costs of Secondary Prophylaxis vs On-demand Therapy With Kogenate Bayer in Patients With Severe Haemophilia A."

Completed·Bayer··NCT02581969·43 enrolled

Unspecified1 trial

Kogenate FS Regulatory Post-Marketing Surveillance

Completed·Bayer··NCT01386268·64 enrolled

Details

Drug Info

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