Sivelestat

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

SepsisCardiovascular Surgery

112 competitors in Sepsis

#DrugCompanyPhaseTrials

1

N-Acetylcysteine (NAC) Treatment

TThe First Affiliated Hospital of Soochow University

Phase 3

12

Kineret

SSwedish Orphan Biovitrum

Phase 2

33

Heparin Sodium

BBaxter Healthcare Corporation

Phase 2

14

Actimmune

HHorizon Therapeutics Ireland DAC

Phase 2

15

Nafamostat Mesylate

EEnsysce Biosciences

Phase 3

26

Hydrocortisone Administration

UUniversity of Virginia

Phase 3

17

Simdax

Orion Corporation, Orion Pharma

Preclinical

18

Zyvox

Pfizer

Preclinical

—9

Zemplar

AbbVie

Preclinical

—10

Primaxin

Pfizer

Preclinical

—Show 27 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Cardiovascular Surgery1 trial

Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI)

Recruiting·NNanjing Medical University·N/A·NCT06195267·500 enrolled

Acute Respiratory Distress Syndrome1 trial

Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Lung Injury or Acute Respiratory Distress Syndrome After Cardiac Surgery

Completed·TThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School·Phase 3·NCT06276569·382 enrolled

Acute Lung Injury1 trial

A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury

Completed·Eli Lilly·Phase 1/2·NCT00036062·600 enrolled

Sepsis1 trial

PALETTE- Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket Trial

Recruiting·AAssistance Publique - Hôpitaux de Paris·Phase 2·NCT06381661·2,000 enrolled

Details

Drug Info

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