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sorfequiline

Phase 2

GGlobal Alliance for TB Drug Development

sorfequiline is one of 9 therapeutic programs targeting Pulmonary TB. It is currently in Phase 2.

2

Indications

2

Total Trials

2

Active Trials

8

Competitors

Pipeline

Status by Indication[2][1]

Indication

Pulmonary TBActive, not recruiting

Tuberculosis, PulmonaryRecruiting

Pulmonary TBPhase 2

Active, not recruiting

Tuberculosis, PulmonaryPhase 2

Recruiting

Competition

Competitive Landscape

8 competitors in Tuberculosis, Pulmonary

#DrugCompanyPhaseTrials

Zyvox

Lamprene

TB Alliance

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Sirturo

Deltyba

Ganfeborole

UUniversity College, London

Avelox

sorfequiline

GGlobal Alliance for TB Drug Development

TBAJ-587

GGlobal Alliance for TB Drug Development

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 2Active, not recruiting

Pulmonary TB

NCT06058299

Q2 2028

Phase 2Recruiting

Tuberculosis, Pulmonary

NCT07672405

Clinical

Trials by Indication[1]

Tuberculosis, Pulmonary1 trial

A Phase 2b, Randomised, Multi-center, Partially Blinded Trial Assessing the Safety and Efficacy of Regimens Containing Sorfequiline, Pretomanid and Linezolid in Adults With Newly Diagnosed, Drug-sensitive, Smear Positive Pulmonary Tuberculosis

Recruiting·GGlobal Alliance for TB Drug Development·Phase 2·NCT07672405·100 enrolled

Pulmonary TB1 trial

A Phase 2, Partially-blinded, Randomised Trial Assessing the Safety and Efficacy of TBAJ-876 or Bedaquiline, in Combination With Pretomanid and Linezolid in Adult Participants With Newly Diagnosed, Drug-sensitive, Smear-positive Pulmonary Tuberculosis

Active, not recruiting·GGlobal Alliance for TB Drug Development·Phase 2·NCT06058299·309 enrolled

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for sorfequiline. U.S. National Library of Medicine, National Institutes of Health.
[2]
Open Targets Platform — Drug–disease associations for sorfequiline. EMBL-EBI & Wellcome Sanger Institute.
[3]
SEC EDGAR — Global Alliance for TB Drug Development company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Highest Phase: Phase 2[1]
Company: GGlobal Alliance for TB Drug Development

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