Sclerosol

(Talc)

ApprovedSmall molecule

SSciarra

Sclerosol is one of 30 small molecule programs targeting Pleural effusion. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Pipeline

Status by Indication[3][1]

Indication

Pleural EffusionActive, not recruiting

Pleural EffusionApproved

Active, not recruiting

Competition

Competitive Landscape

54 competitors in Pleural Effusion

#DrugCompanyPhaseTrials

Avastin

BBio-Thera Solutions

Phase 3

4 2

Vibramycin

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Phase 3

3 3

Opdivo

Bristol-Myers Squibb

Phase 2

2 4

Sclerosol

SSciarra

Approved

3 5

Aleve

Alnylam Pharmaceuticals

Phase 2

1 6

MS Contin

Merck & Co.

Phase 2

1 7

Gemzar

Johnson & Johnson

Phase 2

1 8

Platinol

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Phase 2

4 9

Decadron

AAspen Global Incorporated

Phase 2

2 10

Advil

KKenvue Brands

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2029

Phase 2/3Not yet recruiting

Study completion

NCT06883188

Clinical

Trials by Indication[1]

Pleural effusion3 trials

Efficacy of Iodopovidone Versus Talc in Palliative Malignant Pleural Effusion

Completed·—·Phase 3·NCT02674243·60 enrolled

Talc in Treating Patients With Malignant Pleural Effusion

Completed·AAlliance for Clinical Trials in Oncology·Phase 3·NCT00002622·501 enrolled

Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion

Terminated·—·Phase 4·NCT04792970·4 enrolled

Unspecified1 trial

Stop Air Leak by Talc or Autologous Blood Patch Therapy

Not yet recruiting·—·Phase 2/3·NCT06883188·30 enrolled

Regulatory

FDA Approval Timeline[4]

Dec 24, 1997

SCLEROSOL

NDA NDA020587

Dec 15, 2003

TALC

NDA NDA021388

May 1, 2017

STERITALC

NDA NDA205555

Sources

References

[1]
ClinicalTrials.gov — 4 trial records for Talc. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Talc compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Talc. EMBL-EBI & Wellcome Sanger Institute.
[4]
OpenFDA — FDA approval records (NDA NDA205555). U.S. Food & Drug Administration.
[5]
SEC EDGAR — Sciarra company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: SSciarra

Sclerosol

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2029

Trials by Indication[1]

Pleural effusion3 trials

Unspecified1 trial

FDA Approval Timeline[4]

References

Drug Info

Quick Facts

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